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we decrease » _ decrease (Expand Search), nn decrease (Expand Search), teer decrease (Expand Search)
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173121
Performance on discrimination and reversal tasks are similar for agents with one Q versus G and N matrices.
Published 2023“…Then, the pairing is switched and the agent learns poke <i>right</i> in response to 6 kHz and poke <i>left</i> in response to 10 kHz. <b>A.</b> Mean reward per trial. The reward obtained during the last 20 trials does not differ between agents with one Q versus G and N matrices for discrimination (T = 0.121, P = 0.905, N = 10 each) or reversal (T = -1.194, P = 0.250, N = 10 each). …”
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173122
Simulation of SMARD experiment with comparison to rate-equation estimates.
Published 2012“…A value of one (zero) means that all the molecules are red (green) labeled at a given position. …”
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173123
SPL treatment prevents diabetes-induced glomerular and tubular damage.
Published 2017“…Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was used as loading control for IB. Data are mean±SEM from 3 rats per group. *p<0.05; **p<0.01 and ***p<0.001. …”
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173124
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173125
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173126
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173127
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173128
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173129
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173130
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173131
DataSheet1_Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination.docx
Published 2022“…Moreover, the impact of mRNA COVID-19 vaccines upon the host epigenome remains understudied. Here, we first examined DNA methylation states in the blood of 21 participants prior to and following test-confirmed COVID-19 diagnosis at a median time frame of 8.35 weeks; 756 CpGs were identified as differentially methylated following COVID-19 diagnosis in blood at an FDR adjusted p-value < 0.05. …”
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173132
Table1_Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination.XLSX
Published 2022“…Moreover, the impact of mRNA COVID-19 vaccines upon the host epigenome remains understudied. Here, we first examined DNA methylation states in the blood of 21 participants prior to and following test-confirmed COVID-19 diagnosis at a median time frame of 8.35 weeks; 756 CpGs were identified as differentially methylated following COVID-19 diagnosis in blood at an FDR adjusted p-value < 0.05. …”
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173133
Table2_Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination.XLSX
Published 2022“…Moreover, the impact of mRNA COVID-19 vaccines upon the host epigenome remains understudied. Here, we first examined DNA methylation states in the blood of 21 participants prior to and following test-confirmed COVID-19 diagnosis at a median time frame of 8.35 weeks; 756 CpGs were identified as differentially methylated following COVID-19 diagnosis in blood at an FDR adjusted p-value < 0.05. …”
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173134
(Related to Fig 4) Experimental setups to assay the role of ATGL in lipid droplet lipolysis and HCV assembly and release.
Published 2020“…Cells were lentivirally transduced with the different expression constructs (e.g. empty vector or G0S2 expression vector) and 3 days later infected with the <i>Renilla</i> luciferase (RLuc) reporter JcR2a virus [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008554#ppat.1008554.ref078" target="_blank">78</a>]. …”
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173135
Synthesis and biological evaluation of quinoxaline derivatives as ASK1 inhibitors
Published 2024“…<p>Inhibiting apoptosis signal regulated kinase 1 (ASK1) is an attractive strategy for treating diseases such as non-alcoholic steatohepatitis and multiple sclerosis. Here, we report the discovery of a dibromo substituted quinoxaline fragment containing <b>26e</b> as an effective small-molecule inhibitor of ASK1, with an IC<sub>50</sub> value of 30.17 nM. …”
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173136
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173137
Longitudinal analysis of DR<i>lyp/lyp</i>, DR<i>+/+</i>, F<i>lyp/lyp</i> and F<i>+/+</i> rat islet transcriptomes.
Published 2018“…A p-value of ≤ 0.05 and Z-score greater than 2.0 is significant.…”
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173138
Fragment-based design of small molecule PCSK9 inhibitors using simulated annealing of chemical potential simulations
Published 2019“…<div><p>PCSK9 is a protein secreted by the liver that binds to the low-density lipoprotein receptor (LDLR), causing LDLR internalization, decreasing the clearance of circulating LDL particles. …”
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173139
DataSheet3_Quantifying Iron Oxide Mineral Contents in Miocene Oceanic Red Beds for the Deep-Sea Oxidation Evolution in the South China Sea.XLSX
Published 2022“…The results show that these samples contain 0.20–1.48% hematite (average 0.50%) and 0.30–2.98% goethite (average 1.20%). …”
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173140
DataSheet4_Quantifying Iron Oxide Mineral Contents in Miocene Oceanic Red Beds for the Deep-Sea Oxidation Evolution in the South China Sea.XLSX
Published 2022“…The results show that these samples contain 0.20–1.48% hematite (average 0.50%) and 0.30–2.98% goethite (average 1.20%). …”