Video 2_Case Report: Intra-articular injection of tocilizumab for arthritis treatment in chronic graft-vs.-host disease.mp4 by Mingyu Xie (13868310)

“…Both of his knee joints was injected with tocilizumab at 0, 2, 4, 6, 7, 11, and 19 weeks. Interleukin (IL)-6 levels in the peripheral blood continuously decreased. …”

Video 1_Case Report: Intra-articular injection of tocilizumab for arthritis treatment in chronic graft-vs.-host disease.mp4 by Mingyu Xie (13868310)

“…Both of his knee joints was injected with tocilizumab at 0, 2, 4, 6, 7, 11, and 19 weeks. Interleukin (IL)-6 levels in the peripheral blood continuously decreased. …”

Supplementary Material for: Olfactory bulbs in arthritis model mouse persistently express interleukin-6 before the onset of arthritis: Relationship to food intake by Otani K. (8132178)

“…However, it remains unclear when these abnormalities occur and where they are distributed. In this study, we analyzed spatiotemporal changes in gene expression in the brains of mice with collagen-induced arthritis (CIA). …”

TGF<i>β</i> signaling related genes are involved in hormonal mediation during termite soldier differentiation by Yudai Masuoka (5088671)

“…Although similar expression patterns were observed during each molting process, more than 50 genes were shown to be highly expressed before the presoldier (intermediate stage of soldier) molt. …”

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy by Chen-Hsueh Pai (828204)

“…The high salt-treated wild-type pregnant mice had shown unchanged maternal body weight, hypertension (MAP increase 15 mmHg), and decreased pup weight (~50%) and size (~24%), but these adverse effects were ameliorated in TXAS knockout (KO) mice. …”

Conditional disruption of the <i>P</i>. <i>falciparum RAMA</i> gene. by Emma S. Sherling (7354880)

“…Cycle 0 schizonts were co-stained with anti-RAMA-D antibodies and the anti-RAP1 monoclonal antibody (mAb) 4F3. 4,6-diamidino-2-phenylindole (DAPI) was used as a DNA stain. …”

Intra-arterial pressure during renal reperfusion. by Wouter Willaert (5101937)

“…<p>PP generates lower pressures than diluted PEG (<i>P</i> < 0.05). Ongoing pressure decrease is observed during more than 60 minutes of reperfusion with PP (<i>P</i> = 0.032), whereas the pressure increases further (<i>P</i> < 0.0001) when diluted PEG is used. …”

DataSheet1_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet10_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet7_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet6_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet5_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet4_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet9_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet8_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet2_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet11_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

DataSheet3_Lethal activity of BRD4 PROTAC degrader QCA570 against bladder cancer cells.ZIP by Qiang Wang (32383)

“…QCA570 potently induces degradation of BRD4 protein at nanomolar concentrations, with a DC₅₀ of ∼ 1 nM. It decreases EZH2 and c-MYC levels by transcriptional suppression and protein degradation. …”

The Virological and Immunological Characteristics of the HIV-1-Infected Population in Brazil: From Initial Diagnosis to Impact of Antiretroviral Use by Ricardo Sobhie Diaz (154738)

“…NRTI acquired resistance was 86% in 2001–3 and decreased over time. NNRTI resistance increased from 2001-3(50%) to 2006–9 (60%), PI resistance decreased from 2001–3 (60%) to 2009 (40%), and 3-class resistance was stable over time around 25%. …”

Campomanesia adamantium Peel Extract in Antidiarrheal Activity: The Ability of Inhibition of Heat-Stable Enterotoxin by Polyphenols by Caroline Lescano (3057327)

“…TAD (tadalafil) and FPIPP (antidiarrheal drug) was used as control drugs that increase and decrease cGMP levels, respectively. Results are presented as mean + SEM. n=4-6; One-way ANOVA followed by Tukey´s test; #P <0.05 compared to baseline group; *P <0.05 compared to STa group.…”