<i>Lf</i>^−/− mice demonstrated decreased apoptosis and increased proliferation. by Qiurong Ye (603788)

Complex I activity is increased in cells with elevated NQO1 levels and is decreased by rotenone. by Jiyeong Kim (433042)

Expression of neurotrophins and their receptors was decreased in <i>Slitrk6</i>-deficient inner ear. by Kei-ichi Katayama (257931)

“…The graphs depict mean + SD of 3 independent analyses. The mRNAs of <i>Bdnf</i> and <i>Ntf3</i> were significantly decreased in <i>Slitrk6</i>-deficient inner ear, whereas those of <i>Ntrk2</i> and <i>Ntrk3</i> were not. * <i>p</i><0.05, Student's <i>t</i>-test. …”

Poly I:C stimulation significantly decreased the number of lysozyme positive cells in enteroids. by Julie M. Davies (412514)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

Zebrafish harboring homozygous mutations in <i>gdf6</i> exhibit decreased endurance. by Michèle G. DuVal (278183)

“…</b> Open field tests of average swim velocity during 10 minutes of each hour through a circadian cycle, in tanks replicating lifetime husbandry conditions, show a lower mean movement at night (in either genotype, **p<0.01) but no difference between genotypes in any measure during day (p = 0.247) or night (p = 0.814).…”

Simvastatin decreases cerebral vasospasm of the middle cerebral artery and reduces microthromboemboli after SAH. by Mohammed Sabri (355717)

“…Both pre-SAH and post-SAH treatment with simvastatin significantly decrease microthromboemboli in both cerebral cortex (<i>P</i><0.001) and hippocampus (<i>P</i><0.01) as compared to vehicle treated group. …”

Decreasing neural activity in MBONs that suppress PER when activated has modest effects. by Justine Chia (5459294)

nLTD decreases the molecular proximity between endogenous spine cofilin and F-actin by Barbara Calabrese (553229)

“…Data are expressed as mean ± SEM of the “% FRET” values determined using the Zeiss LSM 510 software module for FRET acceptor photobleaching (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094787#s2" target="_blank">Methods</a>); *p<0.05, **p<0.01 compared to control alone; ^#p<0.05 compared to nLTD alone; ^XXp<0.01 compared to CIN alone, two-way ANOVA, followed by Bonferroni post hoc test., (number of spines: ctrl = 43, nLTD = 29, CIN = 49, CIN+nLTD = 77). …”

rHSP60 decreases viability of B lymphocyte cell line but not macrophage one. by Igor Emiliano L. Souza (18196495)

Hsp90 inhibition decreases the adipogenic transcriptional program without any effect on cytotoxicity. by Sébastien Desarzens (547289)

Total tau levels are significantly decreased in the healthy older brains compared to the younger brains. by Shreyasi Chatterjee (3531506)

Etomoxir and orlistat inhibit cell cycle progression and decreased proliferation rate in myeloma cells. by José Manuel Tirado-Vélez (304970)

Frequency compensation in the feedback scheme of Fig 4a for a stepwise <i>k</i>₂ change (1.0 → 10.0) at background <i>k</i>₁₀ = 0.0. by Melissa Nygård (15374507)

WNF decreases Aβ peptides generation in HEK293 and SH-SY5Y human cells. by Htut Htut Htoo (3686641)

Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>. by Naoto Haruyama (487384)

“…Each column represents the mean ± SD. *p<0.05. WT; wild-type mouse, TgLRAP; LRAP transgenic mouse.…”

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”

DHT increases whereas orchidectomy decreases the weight and cross sectional area of hindlimb muscles. by Young-Eun Yoo (323357)

“…<b>A:</b> In WT mice, DHT increased the GN weight by 7% (212.4±8.8 mg), whereas orchidectomy decreased it by 14% (171.4±9.0 mg) compared with control WT mice (198.4±5.5 mg). …”

Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1. by Neha Goveas (11790822)

“…(B) Percent of weight loss of <i>Mll1</i>^{<i>FC/+; Vil-Cre-ERT2/+</i>} (n = 6) and of <i>Mll1</i>^{<i>FC/FC; Vil-Cre-ERT2/+</i>} (n = 10) mice. Mean ± s.d. is shown (p = 0.007, Student’s <i>t</i>-test). …”

Ethanol decreases hepatic ATP and causes modest liver injury: protection by Alda-1. by Zhi Zhong (314411)