Data_Sheet_1_Endotoxemia-Induced Release of Pro-inflammatory Mediators Are Associated With Increased Glomerular Filtration Rate in Humans in vivo.DOCX by Remi Beunders (9604286)

“…Mean arterial pressure decreased with 13 ± 11 mmHg (p < 0.0001). No significant increase in the urinary excretion of tubular injury markers was observed following LPS administration. …”

Study flow diagram. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Forest plot of LVEDD. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Risk of bias diagram and summary. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Forest plot of NT-pro BNP. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Funnel plot of 6-MWT. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Forest plot of LVEF. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Forest plot of 6-MWT. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

The incidence rate of adverse events. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Basic characteristics of included studies. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Forest plot of LVESD. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Forest plot of clinical efficacy rate. by Lipeng Shi (11307700)

“…Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% <i>CI</i>, 4.88 to 8.04, <i>P</i> < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% <i>CI</i>, -6.55 to -3.01, <i>P</i> < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% <i>CI</i>, -5.98 to -1.99, <i>P</i> < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% <i>CI</i>, -185.30 to -67.03, <i>P</i> < 0.0001). …”

Human mesenchymal stem/stromal cells (hMSCs) increased <i>Ccl2</i> expression and reduced inflammatory responses. by Kazumichi Yagura (4537504)

“…Data are expressed as mean ± SEM. **: <i>P < 0</i>.<i>01</i> (Dunnett’s <i>post hoc</i> test), n.s.: not significant. …”

Insulin effects on taste cell type marker mRNA in taste organoids. by Shingo Takai (7853843)

“…Each score is expressed as mean + SEM. *P<0.05, **P<0.01, ***P<0.001, in post hoc Tukey HDS test.…”

Table_1_Price Elasticity of Bushmeat Demand in the Greater Serengeti Ecosystem: Insights for Managing the Bushmeat Trade.DOCX by Solomon Zena Walelign (3805522)

“…The significant (all at the 0.01 level) own-price elasticities ranges from −1.099 when bushmeat is paired with beef to −0.718 when bushmeat is paired with fish while the significant cross-price elasticities ranges from 0.128 when bushmeat is paired with beef to 0.590 when bushmeat is paired with lamb suggesting that most cross-price relations were inelastic. …”

Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…Survival analysis was performed using the log-rank (Mantel–Cox) test (<b>D</b> and <b>E</b>) relative to sgCTRL (<b>D</b>) and to sgCTRL and sgKDM6A#1 (<b>E</b>). Error bars, SEM (<b>B</b> and <b>C</b>). *, <i>P</i> < 0.05; **, <i>P</i> < 0.01; ***, <i>P</i> < 0.001; ****, <i>P</i> < 0.0001; ns, not significant. …”

Asm inhibition by amitriptyline for 2 weeks of recovery period after 5 weeks cuprizone feeding effects astrogliosis in the CCm. by Marwan Chami (4068142)

“…In addition, <i>Asm</i>-deficient mice expressed similar GFAP protein levels as amitriptyline-treated mice <b>(e and f)</b>.*p<0.05, **p<0.01 and ***p<0.001 amitriptyline-treated vs control-treated groups. …”

HMWHA potentiates but LMWHA inhibits the differentiation of purified monocytes to fibrocytes. by Anu S. Maharjan (342245)

“…The number of fibrocytes per 2.5×10⁵ monocytes in controls from the 3 donors was 4250, 2450, and 1600. * indicates p<0.05 and ** indicates p<0.01 compared to control as determined by t-test. …”

Abnormal glucose uptake in the non-small cell lung cancer patients. by Weishan Zhang (2967174)

“…<p>The increased regions display with red-to-white colour, which include both left and right sides of the insula, putamen, pallidum, thalamus, hippocampus and amygdala, the right side of cerebellum, orbital part of right inferior frontal gyrus and vermis, while the decreased regions display with blue-to-green colour, which include left superior parietal lobule, bilateral inferior parietal lobule, and left fusiform gyrus (p<0.01). …”

Threshold electrotonus (TE) and I/V relationship of the ulnar nerve. by Hsing-Jung Lai (821293)

“…<p><b>A and C</b>, Compared to NC2, the threshold elevation in hyperpolarizing TE of motor axons is reduced in patients (TE_h(10-20ms) and TE_h(20-40ms), -65.2±2.0 mV and -80.4±2.6 mV for patients vs. -71.6±1.0 mV and -89.2±1.3 mV for NC2, <i>p</i> = 0.0043 and 0.0056, respectively). …”