Fig 2 - by Britt-Marie Iresjö (446623)

“…The two High AA treated groups showed significantly increased phenylalanine incorporation compared to Low AA treated cells regardless of IGF-1 levels. Mean±SE. a p< 0.001 vs Low AA siRNA control cells. b p< 0.01 vs High AA siRNA control cells. …”

Overview of experimental design. by Chongwei Chen (2697124)

“…*P<0.05, **P<0.01 versus the non-stretched control group.…”

DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε by Celine S. Weiss (453817)

“…</p><p>Results</p><p>(1) Under baseline conditions eIF2Bε transgenic mice showed no difference in cardiac phenotype compared to wild type, whereas in the mutant eIF2Bε-S⁵³⁵A an increase in LV/tibia length (7.5±0.4 mg/mm vs. 6.2±0.2 mg/mm, p<0.001) and cardiomyocyte cross sectional area (13004±570 vs. 10843±347 RU, p<0.01) was observed. (2) Cardiac overexpression of eIF2Bε did not change the response of the heart to pathologic stress induced by chronic isoproterenol treatment. (3) Cardiac overexpression of the eIF2Bε transgene was followed by overexpression of DYRK2 which is known to prime the inhibitory action of GSK-3β on eIF2Bε, while DYRK1A and GSK-3β itself were not increased. (4) In C57BL/6 mice after 48 h of isoproterenol-stimulation or aortic banding, eIF2Bε was increased and DYRK2 was concomitantly decreased. (5) In line with these in vivo findings, siRNA knockdown of DYRK2 in cultured cardiomyocytes resulted in decreased levels of p(S535)- eIF2Bε, (6) whereas adenoviral induced overexpression of DYRK2 was accompanied by clearly increased phosphorylation of eIF2Bε, indicating a coordinated response pattern (7) Adenoviral induced overexpression of DYRK2 leads to significantly reduced cardiomyocyte size and diminishes hypertrophic response to adrenergic stimulation.…”

Data_Sheet_1_Trend of myopia through different interventions from 2010 to 2050: Findings from Eastern Chinese student surveillance study.docx by Xiyan Zhang (5680457)

Analyses of abiotic stress and brassinosteroid-related some genes in barley roots grown under salinity stress and HBR treatments: Expression profiles and phylogeny by S. Marakli (3615917)

Data_Sheet_1_Galectin-9 Alleviates LPS-Induced Preeclampsia-Like Impairment in Rats via Switching Decidual Macrophage Polarization to M2 Subtype.pdf by Zhi-Hui Li (6192266)

50% reduction of kinesin-1 or dynein is sufficient to perturb neuronal growth. by Gary J. Iacobucci (192833)

“…N = 10 cells; *(#) p<0.05, **(##) p<0.01, ***(###) p<0.001 by two-tailed Student t-test (*) and by Bonferroni’s test (#). …”

Developmental expression pattern of the genes associated with mitochondrial function in the CN. by Kwang H. Choi (121395)

Tornado diagram comparing the relative importance of variables. by Beate Sander (250679)

Analysis of the second dimension of the rate-yield tradeoff. by Chuankai Cheng (6791417)

Data_Sheet_1_Long non-coding RNA SNHG9 regulates viral replication in rhabdomyosarcoma cells infected with enterovirus D68 via miR-150-5p/c-Fos axis.PDF by Huichao Fu (11659595)

Table_3_Unraveling the genetic evolution of SARS-CoV-2 Recombinants using mutational dynamics across the different lineages.XLSX by Varsha Ravi (12267659)

Data Sheet 1_hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways.doc by Yan Yu (56143)

Serological and Genetic Evidence for Altered Complement System Functionality in Systemic Lupus Erythematosus: Findings of the GAPAID Consortium by József Prechl (137307)

PR3 levels are impaired in plasma and PBMCs from Arabs with cardiovascular diseases by Abdelkrim Khadir (437074)

Proteomic Analysis of eIF5B Silencing-Modulated Proteostasis by Xu Jiang (1602100)

Presentation_1_VEGF Production Is Regulated by the AKT/ERK1/2 Signaling Pathway and Controls the Proliferation of Toxoplasma gondii in ARPE-19 Cells.PPTX by Juan-Hua Quan (422684)

Video_1_Behavioral and Molecular Effects Induced by Cannabidiol and Valproate Administration in the GASH/Sal Model of Acute Audiogenic Seizures.MP4 by Giselda Cabral-Pereira (10018847)

Table1_Bifidobacterium longum CECT 7894 Improves the Efficacy of Infliximab for DSS-Induced Colitis via Regulating the Gut Microbiota and Bile Acid Metabolism.DOCX by Fangfei Xiao (11951737)

Table_5_Unraveling the genetic evolution of SARS-CoV-2 Recombinants using mutational dynamics across the different lineages.XLSX by Varsha Ravi (12267659)