Combined KIX domain and c-Myb haploinsufficiency synergistically affects multiple blood lineages. by Lawryn H. Kasper (495452)

“…Asterisks indicate significant p value by pairwise Tukey post test following one way ANOVA (N=13-19 per genotype, * p<0.05, ** p<0.01, *** p<0.001). (H) Epistasis values and 95% confidence intervals calculated using five independent experiments with wild type, c-Myb^+/-, p300^<i>+/KIX</i>;<i>CBP</i>^+/KIX and triple-het <i>p300^+/KIX</i>;<i>CBP^+/KIX</i>;c-Myb^+/- mice represented in each. …”

DES-induced phosphorylation of ERK1/2, stimulation of AHCYL1 and calcium release in chicken oviduct epithelial cells. by Wooyoung Jeong (124130)

“…Then, calcium concentration from the cells was measured. The asterisk denotes a significant effect (***<i>P</i><0.001, **<i>P</i><0.01 and *<i>P</i><0.05). …”

Data_Sheet_1_Berberine Influences Blood Glucose via Modulating the Gut Microbiome in Grass Carp.PDF by Houjun Pan (6683513)

“…Biochemical analysis revealed that fish fed BBR had significantly reduced serum glucose, total cholesterol (TC), and triglyceride (TG) levels, and increased TC (p < 0.05) and TG (p < 0.01) levels in the liver. Deep amplicon sequencing of the V4 region of 16S rRNA genes of the gut microbiota revealed: (i) the composition of gut microbiota after BBR feeding was more diverse than that in the control group; (ii)before fish were fed BBR, the enriched operational taxonomic units (OTUs) mainly belonged to Firmicutes while most enriched OTUs came from Proteobacteria, Planctomycetes, Bacteroidetes, and Firmicutes during BBR feeding and after BBR feeding stopped; (iii) the ratio of Firmicutes to Bacteroidetes was significantly decreased in fish fed BBR. …”

Regulation of endogenous Hox genes by ASH1. by Yujiro Tanaka (194756)

“…Statistically significant differences (Student's t-test) are indicated by asterisks (*: p-value < 0.05, **: p-value < 0.01).</p>…”

Ticagrelor treatment, but not clopidogrel treatment, induces the praroxonase-1 (PON1) message, increases tissue and serum PON1 protein, and mitigates atherosclerosis. by Hasseri Halim (6883436)

“…<p>Abbreviations: CTL, control; CLO, clopidogrel; TIC, ticagrelor; RNA-Seq, RNA sequencing using next generation sequencing; PON1, paraoxonase 1; A.U., arbitrary unit; N = 5 per group; Error bars, means ± SD, statistical analyses performed using one-way ANOVA test with Fisher’s multiple comparisons; <i>NS</i>, not statistically significant; *, P < 0.05; **, P < 0.01 <i>(See also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0218934#pone.0218934.s005" target="_blank">S5 Fig</a>).…”

Lack of CHOP protein does not protect T17M <b><i>RHO</i></b><b> retinas from degeneration, as measured by scotopic ERG responses at 10DB.</b> by Sonali Nashine (408442)

“…<p>We analyzed 4 groups of animals (N = 6). A: The a-wave of the scotopic ERG amplitude was diminished in T17M <i>RHO</i> CHOP−/− mice at 1 month of age and the values of a-wave amplitudes were 456.3 µv ±39.7 in wild-type; 509.1 µv ±24.9 in CHOP−/−; 169.0 µv ±7.9 in T17M <i>RHO</i>; and 54.4 µv ±16.4 in T17M <i>RHO</i> CHOP−/−. …”

Goat Genome scaffolds assembly. by Gwenola Tosser-Klopp (88023)

Reversal of insulin resistance in overweight and obese subjects by trans-resveratrol and hesperetin combination—link to dysglycemia, blood pressure, dyslipidemia, and low-grade inf... by Rabbani, Naila

“…Tumor necrosis factor-α (TNFα) correlated positively with change in fasting plasma glucose (r = 0.70, p < 0.001) and negatively with change in insulin sensitivity (r = −0.68, p < 0.01). …”
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Trends, characteristics, in-hospital outcomes and mortality in surgical mitral valve replacement among patients with and without COPD in Spain (2001-2015) by Javier de-Miguel-Díez (7276307)

“…COPD was associated with a significant increase in IHM, but only among patients who underwent bioprosthetic SMVR (OR 1.32, 95% CI 1.01–1.73).…”

5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells by Krzysztof Poterlowicz (4408261)

Hierarchical clustering of the transcriptional response of BvgAS-regulated genes throughout biofilm development identified by comparing cDNA from planktonic cells to biofilm cells... by Tracy L. Nicholson (120395)

Postoperative complications and mortality [n(%)]. by Qingwen Cao (22439195)

Supplementary Material for: The Effects of Early Postnatal Diuretics Treatment on Kidney Development and Long-Term Kidney Function in Wistar Rats by Bueters R.R.G. (3349739)

“…EUGR resulted in lower body weight from day 3 onwards (-29% at weaning; p < 0.001, -10% at necropsy; p < 0.001), less glomerular generations (4.4 ± 0.32 vs. 5.0 ± 0.423; p = 0.025, males only), decreased glomerular numbers (27,861 ± 3,468 vs. 30,527 ± 4,096; p = 0.026), higher creatinine clearance (0.84 ± 0.1 vs. 0.77 ± 0.09 ml/min/kg; p = 0.047) at 3 months and lower plasma creatinine (25.7 ± 1.8 vs. 27.5 ± 2.8 µmol/l; p = 0.043) at 9 months. …”

TbRRM1 silencing induced cell cycle arrest and apoptosis. by Gabriela V. Levy (784502)

“…Data were analyzed by Student t test compared to 24 h TET- values. *p<0.05; **p<0.01; ***p<0.001.</p>…”

Recovery cycle analysis and regression models demonstrating the refractoriness and relatively refractory period (RRP) against age. by Hsing-Jung Lai (821293)

“…<p><b>A</b>, Compared to NC1 and NC2 (the meaning of symbols are the same as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0141935#pone.0141935.g001" target="_blank">Fig 1</a>), the refractoriness (at 2.5 ms, 91.8±28.0% for patient vs. 27.1±4.5% for NC2, <i>p</i> = 0.007) and relatively refractory period (RRP) (3.59±0.18% for patient vs. 3.04±0.07% for NC2, <i>p</i> = 0.0083) are significantly elevated in motor axons of patients, but not in carriers. …”

Inhibition of intraerythrocytic <i>P. falciparum</i> development by 2-APB. by Masahiro Enomoto (152673)

“…Parasiaemia of ring form (Rf), trophozoites (T), early schizonts (ES) and late schizonts (LS) is shown as mean + S.D. of 3 independent counts of a single well (A) or 3 wells (D, E). Stages with parasitaemia of less than 0.1% are not shown (A, D and E).…”

Impact of optimal 1/week/6 m allopregnanolone treatment regimen on neurogenesis and survival in 3xTgAD male mouse. by Shuhua Chen (11649)

“…CldU positive cells were not significantly increased in both ages suggesting that this APα treatment regimen sustained survival of newly generated cells, and that neurogenic capacity of APα decreased with age. The percentage increase was presented as mean ± SEM; * <i>P</i><0.01; <i>n</i> = 2–5/group.…”

Table_6_Monocyte subtype expression patterns in septic patients with diabetes are distinct from patterns observed in obese patients.docx by Dan Ning (631236)

Presentation_1_The oesophageal adenocarcinoma tumour immune microenvironment dictates outcomes with different modalities of neoadjuvant therapy – results from the AGITG DOCTOR tria... by James M. Lonie (17134759)

Image_2_Effects of Titanium Dioxide Nanoparticles on Porcine Prepubertal Sertoli Cells: An “In Vitro” Study.tif by Francesca Mancuso (6659267)