Stabilization of the Skeletal Muscle Ryanodine Receptor Ion Channel-FKBP12 Complex by the 1,4-Benzothiazepine Derivative S107 by Yingwu Mei (102313)

“…SR vesicles enriched in RyR1 bound ∼48 [³H]S107 per RyR1 tetramer with EC₅₀ ∼52 µM and Hillslope ∼2. The effects of S107 and FKBP12 on RyR1 were examined under conditions that altered the redox state of RyR1. …”

Effect of oxidative stress on functional properties of polarized RPE monolayers. by Parameswaran G. Sreekumar (176748)

“…(E) LDH release measured as a marker for membrane disruption, was significantly higher (<i>p</i><0.001 vs control) with severe oxidative stress, but was unchanged with mild stress. ** denotes <i>p</i><0.01 vs control values. …”

Human Mutations in Mouse Tbx1. by Raquel Castellanos (559734)

“…The G310S mutation led to a smaller but still significant decrease in activation (TR- 2.2 fold decrease, ♦p<0.01; ½SPS- 1.3 fold decrease, ♦p<0.05). …”

Responses to Transient Dopamine and Calcium Elevations by Maria Lindskog (65533)

Performance w.r.t. Number of Realizations. by Ivan Komarov (120593)

Variation in presence of RNA polymerase II in late pachytene XY bodies. by Marieke de Vries (183583)

PDGFR inhibition blocked ISV formation and extension. by Katie M. Wiens (363766)

“…Angiography at 72 hpf showed a decrease in blood circulation through the ISVs in embryos treated with inhV (G). *** indicates p<0.001. …”

Supplementary Material for: Characteristics of Rosacea and Similar Diseases in Patients Wearing Face Masks by Nobeyama Y. (12811124)

DCLK1 regulates angiogenic factors. by Sripathi M. Sureban (455805)

“…Values in the bar graphs in A, B, D and E, are given as average ± SEM, and asterisks denote statistically significant differences (*<i>P</i> < 0.01) compared with Control (NP alone).…”

Evidence for constitutive activation of cytoprotective enzymes network in vitiligo melanocyte cultures. by Barbara Bellei (177809)

“…The stimulation of Cat, Nrf2, HO-1 and SOD2 mRNA was significantly lower in vitiligo cells whereas NQO1 induction was similar. * p≤0.05; ** p≤0.01 <i>versus</i> control.</p>…”

Master Settlement Agreement (MSA) Spending and Tobacco Control Efforts by Jayani Jayawardhana (674830)

“…We use state level data from 50 states and the District of Columbia from four time periods post MSA (1999, 2002, 2004, and 2006) for the analysis. …”

The Impact of Alpha-Syntrophin Deletion on the Changes in Tissue Structure and Extracellular Diffusion Associated with Cell Swelling under Physiological and Pathological Conditions by Lesia Dmytrenko (431060)

“…The deletion of α-syn resulted in a significantly smaller relative decrease in α observed during elevated K⁺ (10 mM) and severe hypotonic stress (−100 mOsmol/l), but not during mild hypotonic stress (−50 mOsmol/l). …”

CK2α Inhibition Down-Regulates Gli1 Expression and Transcriptional Activity. by Shulin Zhang (154810)

“…(H) The transcriptional activity of Hh pathway in A549 detected by Gli reporter assay. A 50% decrease was detected in the presence of 10 µM CX-4945 or 10 µM TBB. * <i>P</i><0.05, ** <i>P</i><0.01, Student’s t-test.…”

Thalidomide lowers BACE1 and reduces β-site cleavage of APP. by Ping He (33281)

“…The density of bands was measured with a significant decrease in C99 fragments (<b>E</b>) but not significant changes of APP levels compared to vehicle groups (<b>F)</b> (Mean ± SD, **<i>p</i><0.01, Students t-test, n = 10 each group).…”

Results of Multivariate Regression Analyses. by Jeet Gandhi (262339)

“…The association coefficient is −0.01, which means after adjusting for <i>EGFR</i> mutation and <i>EGFR</i> copy number effects, the IC50 will decrease 0.98 fold when <i>HER2</i> relative copy number increases 1 unit.…”

Effect of phosphorylation mimicking protein modifications on the rate of Ca²⁺ dissociation from the thin filament. by Bin Liu (5899)

Characterization and partial purification of Secretory IL-12 Inhibitory Factor-4 by Mingyue Wang (90112)

“…Ons and CA-SIIF crude were tested for the effect on IL-12 production of 1 × 10/ml human monocytes. glycoprotein fraction (CA-SIIF-GP) successfully achieved higher inhibitory effect than the non-glycoprotein (CA-SIIF-NGP) fraction (< 0.01). Inhibition efficiency of CA-SIIF-GP fraction is significantly higher compared to CA-SIIF crude and CA-SIIF-NGP (< 0.01). …”

Beta power timecourses time-locked to the response (button press at time zero), expressed as percent change from baseline in the SMOT areas. by Lauren E. Beaton (4763232)

Effects of insulin and IGF-I stimulation on the expression levels of bisecting GlcNAc <i>N</i>-glycans, in general and specifically on E-cadherin. by Julio Cesar Madureira de-Freitas-Junior (489189)

“…Error bars indicate the means + S.E.M. (n = 3). ** = P < 0.01 ANOVA test. …”

Cx43 distribution in CA3 after epileptiform activity. by Erika R. Kinjo (642091)

“…(B, C) Quantification of mean pixel intensity (n = 4 animals per group) showed significant increase in SP and decrease in SR in the acute period (E) compared to controls (D). …”