Autonomic changes in response to carbohydrate ingestion and postural stress (glaucoma N = 37 vs controls N = 36). by Lei Cao (134409)

“…SBP LF power increased and BRS reduced in both glaucoma and control subjects. (*P<0.05, **P<0.01, effect of carbohydrate ingestion; two-way ANOVA). …”

Ngn2 and NeuroD1 mark the initiation and end of amplification of hippocampal DG granule neuroblasts, respectively. by Laurent Roybon (266715)

The first-in-human study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of the factor XI monoclonal antibody SHR-2004 in healthy subjects by Tingting Ma (228102)

“…</p> <p>This randomized, double-blind, dose-escalation, placebo-controlled study evaluated SHR-2004 administered either intravenously (i.v.; Part A) or subcutaneously (s.c.; Part B). In Part A, 24 subjects received a single i.v. dose of SHR-2004 (0.1, 0.3, or 1.0 mg/kg) or placebo. …”

IgG and infectious rate in NHL at baseline, during and after discontinuation of SCIG. by Francesco Cinetto (8638674)

“…Post hoc analysis indicated that SCIG RT significantly increased circulating IgG (panel A) and decreased the annual infectious rate (panel B). …”

BPLF1 promotes the accumulation of SUMOylated TOP2ccs and cell viability following Etoposide treatment. by Jinlin Li (2267896)

“…The expression of catalytically active BPLF1 decreased the toxic effect of Etoposide over a wide range of concentrations while BPLF1^C61A had no appreciable effect. …”

Data_Sheet_1_Impaired tryptophan metabolism in the gastrointestinal tract of patients with critical coronavirus disease 2019.pdf by Yoshihiro Yokoyama (13223913)

“…Stool metabolomic analysis showed that the level of indole-3-propionic acid, a ligand for aryl hydrocarbon receptor (AhR), was markedly decreased in the critical group compared to that in the non-critical group (P = 0.01). …”

Mathematical modeling of nuclear deformation and architecture reorganization. by Sungrim Seirin-Lee (7372355)

“…Inset represents boxplots of the data at <i>Δt</i> = 60. *, statistical difference by the Student's <i>t</i>-test (<i>P</i> < 0.01). (<b>G</b>) Simulation results of nuclei with dynamic deformation with approximately 30% decreased deformability (i.e. 70% deformation) compared to (<b>E</b>) (See <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007289#sec008" target="_blank">Material and Method</a> for more detail). …”

Task versus rest fcMRI analysis for each of the 7 HCP tasks separately. by Takuya Ito (57473)

“…All analyses (in panels A and B) were corrected for multiple comparisons using FDR correction. (*** = FDR-corrected <i>p</i><0.0001; ** = FDR-corrected <i>p</i><0.01; * = FDR-corrected <i>p</i><0.05). …”

DataSheet_1_Elephant grass supplementation in the feed of fattening pigs affects growth performance, carcass characteristics, blood profiles and intestinal microorganisms.docx by Lijuan Gao (5093777)

“…Additionally, pigs fed the CpGui20 diet showed higher (0.01 < P < 0.05) slaughter weight and tended to have increased loin-eye area and lean meat percentage, and, decreased backfat thickness compared with control pigs. …”

Administration of soluble Robo4 (sR4) shifts the Robo4 knockout to the WT phenotype. by Fernanda Gimenez (840629)

“…Data are representative of two independent experiments and show mean values ± SEM (n = 12 mice/group). ***<i>p</i> ≤ 0.001,**<i>p</i> ≤ 0.01,*<i>p</i> ≤ 0.05. Statistical levels of significance were analyzed by one-way ANOVA test with Tuckey’s post hoc test settings.…”

HPK-1 is essential for the transcriptional activation of autophagy. by Ritika Das (4514968)

“…<p>(A) <i>hpk-1</i> is necessary for the induction the autophagy genes <i>atg-18</i> and <i>bec-1</i> (Beclin1) in response to inactivation of TORC1 by <i>daf-15(RNAi)</i> (** indicates p<0.01, Student’s t-test). …”

Tracing Experimentally Compatible Dynamical and Structural Behavior of Atmospheric N₂/O₂ Binary Mixtures within Nanoporous Li–LSX Zeolite: New Insights to Inf... by Mohammad H. Kowsari (1750864)

Tracing Experimentally Compatible Dynamical and Structural Behavior of Atmospheric N₂/O₂ Binary Mixtures within Nanoporous Li–LSX Zeolite: New Insights to Inf... by Mohammad H. Kowsari (1750864)

Prolonged sitting time and all-cause mortality: the mediating and predictive role of kidney function markers by Li Wang (15202)

“…A nonlinear (L-shaped) relationship was observed between eGFR (<i>p</i> < 0.001) or UACR (<i>p</i> < 0.001) and all-cause mortality. …”

HIF-1α is targeted by miR-20b. by Zhang Lei (257727)

“…The specificity of miR-20b to 3′-UTR of HIF-1α mRNA was identified as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007629#s4" target="_blank"><i>Methods</i></a>. *, <i>P</i><0.01, compared with HIF-1α 3′-UTR group.…”

Induction of caFGFR1 in adult cardiomyocytes results in the development of concentric hypertrophy with preservation of systolic function over time. by Sarah N. Cilvik (495882)

“…<p>(A) LV diastolic posterior wall thickness (LVPWd, A) was significantly elevated by one day of induction, while LV mass index (LVMI) was significantly elevated (B) and LV internal diastolic diameter (LVIDd) was significantly decreased (C) within seven days of DOX induction. …”

Up-regulation of FGL2 in PD-1-deficient mice after MHV-3 infection is regulated by IFN-γ and TNF-α. by Yongwen Chen (214708)

“…NS: not significantly different. *<i>p</i><0.05 and **<i>p</i><0.01. n = 5/group.</p>…”

Effects of overexpressing inactive Taspase1 mutants in trans on Taspase1’s processing of various target proteins. by Carolin Bier (166911)

“…., uncleaved indicator protein, significantly decreased upon co-transfection of 0.1 µg Tasp-BFP expression plasmid (***: p<0.0001), no inhibition of cleavage was observed even upon co-transfection of 0.9 µg expression plasmids encoding for the inactive Taspase1 mutants.…”

Land-cover changes and deforestation drivers in the forest landscape of Banmauk township in the Sagaing Region of upper Myanmar by Tin Hnaung Aye (14722501)

“…Mining areas exhibited a considerable increase from 0.37% to 5.35%, while settlement and barren/scrub land areas increased from 0.16% to 0.51% and 1.71% to 7.70%, respectively. …”

Overexpression or knock down of NeuroD protein in the system. by Yue Zhang (30585)

“…The NeuroD cDNA virus increases the total number of NeuroD expressing cells in the DG by 1.8-fold compared to the no-injection control, while NeuroD siRNA decreases the number of NeuroD expressing cells in the DG to 0.53-fold of the control (N = 4,*p<0.05, **p<0.01). …”