Mutation of <i>tp53</i> rescues the female-to-male sex-reversal phenotype of <i>fancl</i> mutants by reducing germ cell apoptosis. by Adriana Rodríguez-Marí (53698)

“…Ovaries of both genotypes had oocytes at different stages of development (i.e.: IB, II, III, IV). Scale bar: 0.1 mm (B,C). (D,E,F) <i>tp53</i> mutation reduces germ cell apoptosis in <i>fancl</i> mutants at 25 dpf. …”

Role of the Gut in the Temporal Changes of β-Cell Function After Gastric Bypass in Individuals With and Without Diabetes Remission by Malini Prasad (11181863)

“…In contrast, both the magnitude and temporal changes in β-cell glucose sensitivity after oral glucose differed by remission status (p=0.04): greater (6.5 fold, p<0.01) and sustained in full remitters, moderate and not sustained past 12 months in partial remitters (3.3 fold, p<0.001), minimal in non-remitters (2.7 fold, p=ns). …”

S1 Fig - by Marie Clémot (18196365)

“…(G) Quantification of early germ cells with pS6 staining in the indicated conditions: <i>mTor</i>::<i>GFP</i>—control (n = 5), <i>mTor</i>::<i>GFP</i> + rapamycin (n = 5), <i>nanos</i>^<i>TS</i><i>>mTor</i>^<i>RNAi1</i> non induced (n = 24), <i>nanos</i>^<i>TS</i><i>>mTor</i>^<i>RNAi1</i> 7 days induction (n = 27), <i>nanos>white</i>^<i>RNAi</i> (n = 8), <i>nanos>iml1</i>^<i>RNAi</i> (n = 18). ** (p<0.01) and **** (p<0.0001) denote statistical significance as determined with Mann-Whitney tests. …”

Table_1_Anethole Attenuates Enterotoxigenic Escherichia coli-Induced Intestinal Barrier Disruption and Intestinal Inflammation via Modification of TLR Signaling and Intestinal Micr... by Qingyuan Yi (10431278)

“…Administration of anethole protected intestinal barrier function and upregulated mucosal layer (mRNA expression of mucin-1 in the jejunum) and tight junction proteins (protein abundance of ZO-1 and Claudin-1 in the ileum) of the piglets challenged with Escherichia coli K88 (P < 0.05). In addition, administration of antibiotics or anethole numerically reduced the plasma concentrations of IL-1β and TNF-α (P < 0.1) and decreased the mRNA expression of TLR5, TLR9, MyD88, IL-1β, TNF-α, IL-6, and IL-10 in the jejunum of the piglets after challenge with Escherichia coli K88 (P < 0.05). …”

Datasheet1_Mean arterial pressure trajectory with premature cardiovascular disease and all-cause mortality in young adults: the Kailuan prospective cohort study.pdf by Zongshuang Song (16975854)

“…The HR (95%CI) for all-cause deaths were 1.27 (0.84–1.94), 2.01 (1.14–3.55), 1.96 (1.04–4.3.72), and 3.28 (1.69–6.37), respectively.…”

<i>ΔmiR-125</i> mutant aging phenotypes are suppressed by loss of <i>chinmo</i>. by Geetanjali Chawla (2935899)

“…MiRNA levels were normalized to 2S rRNA. P values: ** < 0.01; **** < 0.0001. (<b>B</b>) Fold repression of <i>miR-100</i>, <i>let-7</i> and <i>miR-125</i> luciferase sensors in Kc-167 cells transfected with <i>UAS-let-7-C</i> constructs (schematic on left). …”

Table_1_High-Frequency Homologous Recombination Occurred Preferentially in Populus.XLSX by Xining Geng (11295195)

Image_1_Clinical significance of right ventricular–pulmonary arterial coupling in patients with tricuspid regurgitation before closure of atrial septal defect.TIF by Seon Hwa Lee (1687621)

“…On multivariable regression, persistent TR was independently associated with age [odds ratio (OR) 1.07, 95% confidence interval (CI) 1.01–1.14, p = 0.030) and |RV GLS|/PASP (OR 0.001, 95% CI 0.00–0.017, p = 0.012). …”

Image_2_Clinical significance of right ventricular–pulmonary arterial coupling in patients with tricuspid regurgitation before closure of atrial septal defect.TIF by Seon Hwa Lee (1687621)

“…On multivariable regression, persistent TR was independently associated with age [odds ratio (OR) 1.07, 95% confidence interval (CI) 1.01–1.14, p = 0.030) and |RV GLS|/PASP (OR 0.001, 95% CI 0.00–0.017, p = 0.012). …”

Health Risks of Low-Dose Dietary Exposure to Triphenyl Phosphate and Diphenyl Phosphate in Mice: Insights from the Gut–Liver Axis by Jing Cao (287196)

“…Here, C57BL/6J male mice were exposed to TPHP or DPHP for 12 weeks at estimated daily intake doses of 0.1 and 7 μg/kg bw/day. TPHP intake affected the levels of short-chain fatty acids and bile acids in the gut, enhancing the production of 29 medium- and long-chain fatty acids in the liver by 3.72-fold and significantly increasing hepatic lipid and cholesterol levels. …”

DataSheet1_Evolution of Frequency and Intensity of Concurrent Heavy Precipitation and Storm Surge at the Global Scale: Implications for Compound Floods.PDF by Yangchen Lai (11157456)

“…Results show that the annual number of compound flood days increased significantly by 1–4 per decade (α = 0.1) on the east coast of the US and northern Europe, while the annual number of compound flood days decreased significantly in southern Europe and Japan. …”

Table_1_Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice.docx by Jiuyang Chang (10283804)

“…We found that addition of 0.01% 7KC either in chow diet (CD, regular chow diet with 1% cholesterol) or western type diet (WD, high fat diet with 1% cholesterol) accelerated hepatic neutral lipid accumulation by Oil Red O staining. …”

Image_2_Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice.tif by Jiuyang Chang (10283804)

“…We found that addition of 0.01% 7KC either in chow diet (CD, regular chow diet with 1% cholesterol) or western type diet (WD, high fat diet with 1% cholesterol) accelerated hepatic neutral lipid accumulation by Oil Red O staining. …”

Image_1_Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice.tif by Jiuyang Chang (10283804)

“…We found that addition of 0.01% 7KC either in chow diet (CD, regular chow diet with 1% cholesterol) or western type diet (WD, high fat diet with 1% cholesterol) accelerated hepatic neutral lipid accumulation by Oil Red O staining. …”

DataSheet1_Evolution of Frequency and Intensity of Concurrent Heavy Precipitation and Storm Surge at the Global Scale: Implications for Compound Floods.PDF by Yangchen Lai (11157456)

“…Results show that the annual number of compound flood days increased significantly by 1–4 per decade (α = 0.1) on the east coast of the US and northern Europe, while the annual number of compound flood days decreased significantly in southern Europe and Japan. …”

DataSheet1_Chitosan induced cold tolerance in Kobresia pygmaea by regulating photosynthesis, antioxidant performance, and chloroplast ultrastructure.xlsx by Shuo Li (143148)

“…Under regular temperatures, low concentrations of CTS (0.005% and 0.01%) inhibited the soluble protein content, ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco, EC 4.1.1.39) activity, and photosynthetic capacity. …”

DataSheet2_Chitosan induced cold tolerance in Kobresia pygmaea by regulating photosynthesis, antioxidant performance, and chloroplast ultrastructure.docx by Shuo Li (143148)

“…Under regular temperatures, low concentrations of CTS (0.005% and 0.01%) inhibited the soluble protein content, ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco, EC 4.1.1.39) activity, and photosynthetic capacity. …”

Data_Sheet_1_Reactive Oxygen Species Penetrate Persister Cell Membranes of Escherichia coli for Effective Cell Killing.docx by Aki Kawano (9393035)

“…These results clearly revealed that ROS sterilizes persister cells more effectively compared to the sterilization of exponential cells (^**p < 0.01). These ROS do not injure the bacterial cell wall but rather invade the cell, followed by cell killing. …”

Data Sheet 1_Dynamic stability of gut microbiota in elite volleyball athletes: microbial adaptations during training, competition and recovery.pdf by Junior Carlone (22173565)

“…</p>Methods<p>Seven elite athletes from the Italian Men's SuperLega Championship (age: 26.5 ± 4.5 years; weight: 96 ± 11 kg; height: 200 ± 0.1 cm; BMI: 24 ± 1.9) were monitored at four timepoints over eight weeks Regular Season periods (T0, T1), Rest Period (T2) and International Tournament Period (T3). …”

Table_1_Trends in the rate of regular exercise among adults: results from chronic disease and risk factor surveillance from 2010 to 2018 in Jiangsu, China.DOCX by Jian Su (86223)

“…The weighted rate of regular exercise was 12.28% (95% confidence interval [CI]: 9.11–15.45%) in 2010 and 21.47% (95% CI, 17.26–25.69%) in 2018, showing an overall increasing trend (P for trend = 0.009). Nevertheless, stratification analysis showed that the regular exercise rate decreased from 33.79% in 2010 to 29.78% in 2018 among retired adults. …”