Metformin enhances epithelial cell growth inhibition via the protein kinase–insulin-like growth factor binding protein-1 pathway by Xuping Shao (18136294)

“…In an EcSC IGFBP1 overexpression model, the ability of EcSCs to inhibit epithelial cell proliferation was enhanced (EdU positivity decreased from 38% to 25%, <i>p</i> = .0001). …”

Image_1_Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis.JPEG by Jian-Jun Lv (7488479)

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic by Aaron Mobley (412870)

“…We found that ∼50% of respondents had experienced at least one episode of the inability to reproduce published data; many who pursued this issue with the original authors were never able to identify the reason for the lack of reproducibility; some were even met with a less than “collegial” interaction.…”

UV Reconfigurable Shape Memory Polyurethane with a High Recovery Ratio under Large Deformation by Jing Hu (41899)

Table_1_Genome-wide DNA methylation pattern in whole blood of patients with Hashimoto thyroiditis.docx by Zheng Zhou (152309)

“…Further analysis exposed a noteworthy concentration of hypermethylated DMPs in the 3´UTR, North Shore, and CpG islands, while there was a significant decrease in the Open Sea (all P < 0.001). …”

HIV Clinical Pathway: A New Approach to Combine Guidelines and Sustainability of Anti-Retroviral Treatment in Italy by Davide Croce (383177)

“…From an economic point of view, the CP implementation led to a substantial advantage: the mean total costs related to the management of the HIV disease (ART, hospital admission and laboratory tests) decreased (-8.60%) in the Post-CP phase (p-value < 0.0001). …”

Pediatric scorpionism in northern Amazonia: a 16-year study on epidemiological, environmental and clinical aspects by Jules Vaucel (10411049)

“…Methods: We conducted a monocentric descriptive retrospective study on scorpion stings in all pediatric patients admitted to Cayenne General Hospital from January 1, 2002 to December 31, 2018. …”

Severe Hypoglycemia in a Juvenile Diabetic Rat Model: Presence and Severity of Seizures Are Associated with Mortality by Margaret Maheandiran (503654)

“…However, the BG at seizure onset was statistically similar between STZ (1.8±0.2 mM) and CON animals (1.6±0.1 mM) as well as between those that survived (S+S) and those that died (S+M) post-seizure. …”

table1_Attribution of the Principal Components of the Summertime Ozone Valley in the Upper Troposphere and Lower Stratosphere.xlsx by Shujie Chang (10018958)

Presentation_1_Chronic Hepatitis C Pathogenesis: Immune Response in the Liver Microenvironment and Peripheral Compartment.pdf by Daniela Alejandra Rios (11221557)

Image_1_Mitigation of water scarcity with sustained growth of Rice by plant growth promoting bacteria.jpeg by Naima Mahreen (11568496)

Toward Computationally Designed Self-Reporting Biosensors Using Leave-One-Out Green Fluorescent Protein by Yao-ming Huang (1512265)

“…Leave-one-out green fluorescent protein (LOO<i>n</i>-GFP) is a circularly permuted and truncated GFP lacking the <i>n</i>th β-strand element. …”

Characterisation of medication side effects in patients with mostly resistant depression in a real-world setting by Fabio Panariello (11880279)

(A) Evidence and types of selection: (Top) Schematic of the lowest mean value fractional rank value (λ) distributions for local heterozygosity in a sample of 45 European Americans... by Taras K. Oleksyk (53041)

Data_Sheet_1_Dietary Lasia spinosa Thw. Improves Growth Performance in Broilers.ZIP by Lang Zhang (37998)

“…Results indicated that the average daily feed intake of broilers during 22–42 days and the average daily gain of chickens during 1–42 days significantly increased by dietary supplementation of LST powder (p < 0.01), while the feed conversion ratio during the overall periods was decreased by dietary supplementation of LST powder (p < 0.01). …”

Aβ42 binds to and impairs ABAD activity, while HA (human amylin) does not. by Yun-An Lim (337762)

“…Results are means ± SE, (n = 5 to 6 per group), <b>**</b>, <i>P</i><0.01 (B) Pull-down of ABAD from SH-SY5Y cells shows that different from HA, Aβ42 can bind to ABAD <i>in vitro</i>. …”

Anatomical Specializations for Nocturnality in a Critically Endangered Parrot, the Kakapo (<em>Strigops habroptilus</em>) by Jeremy R. Corfield (210219)

BCL11A expression was negatively regulated by hsa-miR-190b-5p. by Meihuan Chen (15456926)

“…Compared with negative control mimics or negative control inhibitors, *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001.…”

Table_1_Dietary Supplementation With Bacillus subtilis Promotes Growth and Gut Health of Weaned Piglets.pdf by Zhilong Tian (9990485)

Image_2_Efficacy and safety of COVID-19 inactivated vaccine: A meta-analysis.JPEG by Xiaoming Li (7401)

“…The results of the meta-analysis showed that: in terms of effectiveness evaluation, two doses of COVID-19 inactivated vaccines decreased the symptomatic infection [relative risk (RR) = 0.23, 95% confidence interval (CI) (0.18,0.30), P < 0.00001], asymptomatic infection [RR = 0.48, 95%CI (0.32, 0.74), P = 0.0008], total infection [RR = 0.32, 95%CI (0.24, 0.41), P < 0.00001] and hospitalization [RR = 0.06, 95%CI (0.01, 0.27), P = 0.0002] for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) significantly. …”