Image1_Grape seed proanthocyanidin extract targets p66Shc to regulate mitochondrial biogenesis and dynamics in diabetic kidney disease.PNG by Yiyun Song (14336670)

Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif by Marcela Rios-Carlos (22759823)

“…AFs (0.1, 1, 5 g/kg) from Agave tequilana Weber var. azul were orally administered for 13 days. …”

Analysis of targeted MLX deletion in Sertoli cells. by Patrick A. Carroll (11586792)

“…Shown for all panels is the mean with SEM with <i>p</i>-values shown from paired <i>t</i> test, except for 4K that was an unpaired <i>t</i> test (* <i>p</i> < 0.05, ** <i>p</i> < 0.01, *** <i>p</i> < 0.001, *** <i>p</i> < 0.0001). …”

DataSheet_1_Case report: Successful treatment of ulcerative colitis-related post-colectomy enteritis refractory to multiple therapies with ustekinumab.pdf by Chenglin Guo (5776340)

Results of the SHIRPA screen on Pv-Δγ2 and Pv-Δγ2-partial rescue mice compared with control γ2I77 mice. by Elli Leppä (206847)

“…</p><p>*p<0.05,</p><p>**p<0.01,</p><p>***p<0.001 for the significance of the difference between Pv-Δγ2 or Pv-Δγ2-partial rescue and control γ2I77 mice (Mann-Whitney U-test, Wilcoxon signed rank test or Student's <i>t</i>-test). n = 15–22 per line.…”

DataSheet_1_Silencing an aphid-specific gene SmDSR33 for aphid control through plant-mediated RNAi in wheat.docx by Jiahui Zhang (3163929)

DataSheet_1_Reactive oxygen species may be involved in the distinctive biological effects of different doses of 12C6+ ion beams on Arabidopsis.docx by Yue Yin (320688)

Chemotherapy Drug Induced Discoordination of Mitochondrial Life Cycle Detected by Cardiolipin Fluctuation by Yu-Jen Chao (665872)

“…<div><p>Chemotherapy drugs have been prescribed for the systemic treatment of cancer. We selected three chemotherapy drugs, including methotrexate, mitomycine C and vincristine to inhibit the proliferation of HT1080 human fibrosarcoma cells in S, G2 and M phases of the cell cycle respectively. …”

Image_5_Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5.tif by Renato Simões Gaspar (8384040)

Table 2_Effects of the HEP® (Homeostasis–Enrichment–Plasticity) Approach in preterm infants with increased developmental risk: a randomized controlled study.docx by Gamze Cagla Sirma (21432837)

Table 2_Epigenetic age acceleration and neurotrophin signaling pathways in cancer-related cognitive impairment: a longitudinal, prospective cohort study.docx by Michael Sayer (11493436)

Table_2_The Splenic Marginal Zone in Children Is Characterized by a Subpopulation of CD27-Negative, Lowly IGHV-Mutated B Cells.xlsx by Artur Kibler (12004835)

Mutations altering LTD dynamics impair their lipid transport properties (a) Design of the STARD11-5P mutant at the omega loop (pink). by Sriraksha Srinivasan (7535654)

“…(<i>n</i> = 3; data are means ± SD; *<i>p</i> < 0.05, **<i>p</i> < 0.01; ***<i>p</i> < 0.001 [ordinary one-way ANOVA]). …”

CB2R inhibits the production of IL-1β but not IL-6 and TNF-α in cultured peritoneal macrophages stimulated with LPS/DSS. by Ping Ke (3110763)

“…In another set of experiments, peritoneal macrophages from WT mice and CB2R KO mice were isolated and stimulated with/without LPS/DSS for 24 h. The levels of IL-1β, IL-6 and TNF-α were measured by ELISA. (A-C) Pre-incubated with HU 308 significantly decreased the level of IL-1β but have no effect on the levels of IL-6 and TNF-α. n = 6 per group. …”

DataSheet1_D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis.pdf by Yuqing Lu (1282527)

DataSheet_1_The effect of two-year application of pelargonic acid on the growth of Cirsium arvense (L.) Scop. and Sonchus arvensis L.docx by Eliyeh Ganji (17875571)

Table_1_Transcriptome and proteome profile of jejunum in chickens challenged with Salmonella Typhimurium revealed the effects of dietary bilberry anthocyanin on immune function.DOC... by Sheng Zhang (111330)

“…Typhimurium infection (P < 0.01). (2) Supplementation with BA reduced the relative weight of the bursa of Fabricius (P < 0.01) and jejunal villus height (P < 0.05) and increased the number of goblet cells (P < 0.01) and the expression of MUC2 (P < 0.05) in jejunal mucosa, compared with birds in SI. (3) Supplementation with BA decreased (P < 0.05) the concentration of immunoglobulins and cytokines in plasma (IgA, IL-1β, IL-8, and IFN-β) and jejunal mucosa (IgG, IgM, sIgA, IL-1β, IL-6, IL-8, TNF-α, IFN-β, and IFN-γ) of S. …”

Effect of polydatin on the mRNA expression of PPARβ, eNOS and iNOS under HG (glucose at 55 mmol/L) conditions. by Yang Wu (66682)

“…<p>Co-incubation with polydatin (1, 3, or 10 μmol/L) in HG-stimulated aortas markedly upregulated the decreased <i>PPARβ</i> and <i>eNOS</i> mRNA levels, and reduced the <i>iNOS</i> level in a dose-dependent manner. …”

Image_1_Dragon fruit-kiwi fermented beverage: In vitro digestion, untargeted metabolome analysis and anti-aging activity in Caenorhabditis elegans.JPEG by Zizhong Tang (4104571)

“…Finally, compared with the control group, although the original concentration of FB has a side-toxic effect on nematodes, the mean lifespan of C. elegans fed with 1.56% FB increased by 18.01%, SOD activity significantly increased by 96.16% and MDA content significantly decreased by 40.62%. …”

Data_Sheet_1_Asthmatic Bronchial Smooth Muscle Increases CCL5-Dependent Monocyte Migration in Response to Rhinovirus-Infected Epithelium.docx by Benoit Allard (522753)

“…Inflammation triggered by HRV infection (HRV-16, MOI 0.1, 1 h) was assessed at 24 h with transcriptomic analysis and multiplex ELISA. …”