Image_1_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.pdf by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Image_2_Neutrophil depletion in the pre-implantation phase impairs pregnancy index, placenta and fetus development.jpeg by Cristina Bichels Hebeda (5931599)

“…On gestational day 5.5, neutrophil depletion impaired the blastocyst implantation, as 50% of pregnant mice presented reduced implantation sites. …”

Optical Imaging of Phase Transition and Li-Ion Diffusion Kinetics of Single LiCoO₂ Nanoparticles During Electrochemical Cycling by Dan Jiang (139681)

“…Traditional electrochemical studies were often based on a bulk electrode consisting of billions of electroactive nanoparticles, which washed out the intrinsic heterogeneity among individuals. Here, we employ optical microscopy, termed surface plasmon resonance microscopy (SPRM), to image electrochemical current of single LiCoO₂ nanoparticles down to 50 fA during electrochemical cycling, from which the phase transition and Li-ion diffusion kinetics can be quantitatively resolved in a single nanoparticle, in operando and high throughput manner. …”

2‑Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes) by Yu Li (183836)

“…Although high concentrations of 2-ethylhexyl diphenyl phosphate (EHDPP) have been detected in wild fish, its reproductive toxicity in fish remains unclear. In this study, we for the first time observed that EHDPP elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration of 37.5 μM. 2-Ethyl-5-hydroxyhexyl diphenyl phosphate was proved to be the dominant metabolite of EHDPP in Japanese medaka and elicited 3.1-fold stronger AR antagonistic activity than that of EHDPP. …”

Image 1_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.tif by Joachim Müller (265589)

“…Few reports exist on the molecular bases that govern this adaptation. Herein, we analyzed the T. gondii proteomes of different isolates at two timepoints during cell culture adaptation.…”

Video_6_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…However, how NET formation is triggered by HIV in different tissues and whether this mechanism is affected by aging remain unknown. We demonstrate that the mechanisms that trigger NET release in response to HIV are different in blood and genital tissues, and that NET release decreases with aging. …”

Table_4_Bt GS57 Interaction With Gut Microbiota Accelerates Spodoptera exigua Mortality.XLS by Yazi Li (4162948)

“…In turn, loss of gut microbiota significantly decreased the B. thuringiensis susceptibility of S. exigua larvae. …”

Data Sheet 1_Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training.pdf by Irina A. Strigo (9745472)

“…Functional MRI data during experimental heat pain on the left forearm were collected and analyzed, comparing responders (≥50% reduction in PEG scores) and non-responders.…”

Image_2_Altered Intra- and Inter-Network Connectivity in Drug-Naïve Patients With Early Parkinson’s Disease.TIF by Weiqi Zeng (4386472)

“…Intra-network analysis indicated decreased functional connectivity in DGN, SMN, LBN, and ventral attention networks (VAN). …”

Data Sheet 1_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.pdf by Yali Han (4676677)

“…Cervical cancer saw a slight increase in ASIR (EAPC: 0.88), a substantial increase in ASPR (EAPC: 2.50), but decreases in ASMR and ASDR (EAPC: −1.05 and −1.07). …”

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity by Brandon L. Probst (727964)

“…At higher concentrations, RTA 408 inhibited tumor cell growth (GI₅₀ = 260 ± 74 nM) and increased caspase activity in tumor cell lines, but not in normal primary human cells. …”

Data Sheet 1_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Methods<p>Utilizing random sampling, we conducted questionnaire surveys among primary care physicians from Guangxis primary medical institutions in June 2019 and October 2022, and analyzed the data with SPSS software.…”

Table_2_Examining the associations between mental health, life balance, work-method autonomy, and perceived boundary control among postdoctoral fellows.DOCX by Brian K. Lo (20449568)

“…Both work-method autonomy and perceived boundary control were positively associated with life balance [B = 0.40, 95% CI = [0.20–0.60]; B = 0.50, 95% CI = [0.32–0.67], respectively]. Postdocs with greater life balance had decreased odds of reporting mood disorder symptoms [anxiety disorder symptoms: adjusted OR = 0.55, 95% CI = (0.37–0.82); depressive disorder symptoms: adjusted OR = 0.31, 95% CI = (0.18–0.55); anxiety-or-depressive disorder symptoms: adjusted OR = 0.42, 95% CI = (0.27–0.65)]. …”

Table 1_Impact of catheter-to-vein diameter ratio on thrombosis in pediatric central venous catheterization.pdf by Fevzi Kahveci (15121585)

“…</p>Results<p>A total of 50 patients were included in our study. Thrombosis was observed in 34% of the patients. …”

Data_Sheet_2_Changes in the gut microbiota of forest musk deer (Moschus berezovskii) during ex situ conservation.ZIP by Yuanlin Jiang (13758802)

“…Thus, ex situ conservation efforts were conducted in 2016 whereby approximately 50 individuals were artificially migrated from Weinan, Shaanxi to Huailai, Hebei. …”

DataSheet1_Biomechanical Properties of Mouse Carotid Arteries With Diet-Induced Metabolic Syndrome and Aging.PDF by Anastasia Gkousioudi (12272495)

“…Our study showed that aging is a dominant factor affecting arterial remodeling in the adult and old mice, to a similar extent, with stiffening manifested with a significantly reduced capability of energy storage by ∼50% (p < 0.05) and decreases in material stiffness and stress (p < 0.05), regardless of diet. …”

Image_3_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

Probing the Sensitivity of the Orbitrap Lumos Mass Spectrometer Using a Standard Reference Protein in a Complex Background by Michaella J. Levy (1564081)

“…Furthermore, the total number of proteins identified from decreasing starting amounts of whole cell extracts was determined. …”

Table_1_Nutritional management of glycogen storage disease type III: a case report and a critical appraisal of the literature.docx by Elena Massimino (15457904)

“…After a 2-year follow-up, all biomarkers of muscle and heart damage markedly decreased (by 50–75%), glucose levels remained within the normal range and lipid profile was unchanged. …”

Image_1_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”