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63261
MicroRNA-451a, microRNA-34a-5p, and microRNA-221-3p as predictors of response to antidepressant treatment
Published 2018“…Paroxetine was markedly effective in 50 patients who also displayed an increased level of miRNA-451a but reduced levels of miRNA-34a-5p and miRNA-221-3p. …”
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63262
Data_Sheet_2_Bacteroides abundance drives birth mode dependent infant gut microbiota developmental trajectories.xlsx
Published 2022“…However, we did not observe an increase in functional alpha diversity, which was stable and comparable with the mother samples throughout all the sampling points. …”
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63263
DataSheet4_Overall Survival Prediction of Advanced Cancer Patients by Selection of the Most Significant Baseline Serum Biomarker Combination.pdf
Published 2022“…</p><p>Conclusion: Based on our analysis, we can confirm that the complex monitoring of CRP, albumin, and PLR would provide a good estimation of OS. …”
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63264
datasheet3_Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking.pdf
Published 2020“…Herein, we show that lonafarnib dose dependently enhances the amplitude of ACh-evoked inward currents (I<sub>ACh</sub>), owning to the increased α7nAChR expression and membrane trafficking. …”
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63265
DataSheet1_Macleayins A From Macleaya Promotes Cell Apoptosis Through Wnt/β-Catenin Signaling Pathway and Inhibits Proliferation, Migration, and Invasion in Cervical Cancer HeLa Ce...
Published 2021“…The Wnt/β-catenin signaling cascade activation was verified using the Dual-Glo® Luciferase assay. We found that MA inhibited the growth of HeLa cells at 72 h (IC<sub>50</sub> = 26.88 µM) via inducing apoptotic process, reduced the proliferation rate by 29.89%, and decreased the cells migration and invasion as compared to the untreated group. …”
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63266
datasheet1_Farnesyl Transferase Inhibitor Lonafarnib Enhances α7nAChR Expression Through Inhibiting DNA Methylation of CHRNA7 and Increases α7nAChR Membrane Trafficking.xlsx
Published 2020“…Herein, we show that lonafarnib dose dependently enhances the amplitude of ACh-evoked inward currents (I<sub>ACh</sub>), owning to the increased α7nAChR expression and membrane trafficking. …”
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63267
Image 7_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”
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63268
Image 8_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”
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63269
Granulocyte Colony-Stimulating Factor Reduces Fibrosis in a Mouse Model of Chronic Pancreatitis
Published 2014“…</p><p>Results</p><p>The pancreatic collagen expression were significantly decreased in the G-CSF-treated group sacrificed at week 9. …”
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63270
Supplementary Material for: Gintonin Attenuates D-Galactose-Induced Hippocampal Senescence by Improving Long-Term Hippocampal Potentiation, Neurogenesis, and Cognitive Functions
Published 2018“…We performed histological analyses, LTP measurements, and object location test. …”
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63271
High-Quality Three-Dimensionally Cultured Cells Using Interfaces of Diblock Copolymers Containing Different Ratios of Zwitterionic <i>N</i>‑Oxides
Published 2024“…Interestingly, the expression of undifferentiated markers of hUC-MSCs was higher on surfaces that adsorbed proteins to some extent and formed 50–150 μm spheroids in the range of 40–70% of <i>N</i>-oxide ratio. …”
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63272
DataSheet1_The Influence of CYP3A4 Genetic Polymorphism and Proton Pump Inhibitors on Osimertinib Metabolism.docx
Published 2022“…In an in vivo study, Sprague–Dawley (SD) rats were randomly divided into groups, with six animals per group, receiving osimertinib with or without rabeprazole, omeprazole, and lansoprazole. We found that the AUC<sub>(0–t)</sub>, AUC<sub>(0–∞)</sub>, and C<sub>max</sub> of osimertinib decreased significantly after co-administration with rabeprazole orally, but they increased remarkably when osimertinib was administered through intraperitoneal injection. …”
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63273
Data_Sheet_1_Corticotrophin-Releasing Factor Modulates the Facial Stimulation-Evoked Molecular Layer Interneuron-Purkinje Cell Synaptic Transmission in vivo in Mice.PDF
Published 2020“…Microapplication of CRF in cerebellar cortical molecular layer induced increases in amplitude of P1 and pause of SS firing. The CRF decreases in amplitude of P1 waveform were in a dose-dependent manner with the EC<sub>50</sub> of 241 nM. …”
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63274
Data_Sheet_1_Bacteroides abundance drives birth mode dependent infant gut microbiota developmental trajectories.XLSX
Published 2022“…However, we did not observe an increase in functional alpha diversity, which was stable and comparable with the mother samples throughout all the sampling points. …”
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63275
Data_Sheet_1_Donor-Related Risk Factors for Graft Decompensation Following Descemet's Stripping Automated Endothelial Keratoplasty.PDF
Published 2022“…This failure was associated with donor pseudophakic lens status (hazard ratio [HR]; 2.67, CI; 1.50–4.76, P = 0.001) and preoperative endothelial folds (HR; 2.82, CI; 1.20–6.62, P = 0.02). …”
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63276
DataSheet1_The Relationship Between Low-Density Lipoprotein Cholesterol and Progression of Mild Cognitive Impairment: The Influence of rs6859 in PVRL2.docx
Published 2022“…This study aims to investigate the effects of cholesterol and genetic risk factors on progression of mild cognitive impairment (MCI) to AD.</p><p>Methods: We prospectively followed 316 MCI participants aged ≥50 years with a baseline cholesterol profile and SNP genotyping data for 4.5 years on average in a sub-cohort of the Shanghai Aging Study. …”
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63277
Image_4_Identification and Functional Characterization of Sugarcane Invertase Inhibitor (ShINH1): A Potential Candidate for Reducing Pre- and Post-harvest Loss of Sucrose in Sugarc...
Published 2018“…INVINH proteins are small (18 kDa) members of the pectin methylesterase inhibitor superfamily and they are moderately conserved across plants. In the present study, we identified two INVINH genes from sugarcane, ShINH1 and ShINH2. …”
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63278
Image_1_Human Umbilical Cord Therapy Improves Long-Term Behavioral Outcomes Following Neonatal Hypoxic Ischemic Brain Injury.pdf
Published 2019“…Behavioral tests, including negative geotaxis, forelimb preference and open field test, were performed on PND 14, 30, and 50, following brains were collected for assessment of neuropathology.…”
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63279
High-Quality Three-Dimensionally Cultured Cells Using Interfaces of Diblock Copolymers Containing Different Ratios of Zwitterionic <i>N</i>‑Oxides
Published 2024“…Interestingly, the expression of undifferentiated markers of hUC-MSCs was higher on surfaces that adsorbed proteins to some extent and formed 50–150 μm spheroids in the range of 40–70% of <i>N</i>-oxide ratio. …”
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63280
S1 Data -
Published 2024“…</p><p>Results</p><p>Among 609 infected healthcare workers, they were predominantly female (71.8%), Malays (84.6%), and aged 18–39 years (70.1%). 50.7% of infected healthcare workers experienced PACS. …”