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63301
Conjugate vaccine serotypes persist as major causes of non-invasive pneumococcal pneumonia in Portugal despite declines in serotypes 3 and 19A (2012-2015)
Published 2018“…There were 50 serotypes among the 1435 isolates. The most common were serotypes: 3 (14%), 11A (8%), 19F (6%), 23A (5%), 6C (5%), 19A (4%), 23B (4%), 9N (4%) and non-typable isolates (4%). …”
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63302
Data_Sheet_1_Abnormal expression of cortical cell cycle regulators underlying anxiety and depressive-like behavior in mice exposed to chronic stress.PDF
Published 2022“…</p>Methods<p>Prefrontal cortex mRNA and protein levels of p16<sup>INK4A</sup> and p21<sup>Waf1/Cip1</sup> of mice (six independent groups of C57BL/6J, eight mice/group, 50% female) exposed from 0 to 35 days of chronic restraint stress (CRS) were quantified by qPCR and Western Blot, respectively. …”
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63303
Image_1_Identification and Functional Characterization of Sugarcane Invertase Inhibitor (ShINH1): A Potential Candidate for Reducing Pre- and Post-harvest Loss of Sucrose in Sugarc...
Published 2018“…INVINH proteins are small (18 kDa) members of the pectin methylesterase inhibitor superfamily and they are moderately conserved across plants. In the present study, we identified two INVINH genes from sugarcane, ShINH1 and ShINH2. …”
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63304
Data_Sheet_1_Resistance to preservatives and the viable but non-culturable state formation of Asaia lannensis in flavored syrups.ZIP
Published 2024“…WLS1-1 was resistant to PS, SB and SS with an MIC of 4.0, 2.0 and 0.5 g/L at pH 5.0, respectively. The MIC values exceed the maximum permissible concentrations that can be added. …”
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63305
Image_1_Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model.TIF
Published 2019“…Accordingly, lower virus replication, decreased presence in bronchioli and parenchyma and lower leukocytes and epithelial infected cells were found in the lungs of HA mut-infected animals. …”
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63306
Table_4_Precision medicine based on the phenotypic differences in peripheral T helper cells in patients with psoriatic arthritis: One year follow-up outcomes.DOCX
Published 2022“…Purpose<p>We validated the one-year effectiveness of strategic treatment with biological disease-modifying anti-rheumatic drugs (bDMARDs) based on peripheral T-lymphocytic phenotyping and explored the impact of treatment on T helper lymphocytic phenotypes.…”
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63307
Presentation_1_Environmental Concentrations of Sulfonamides Can Alter Bacterial Structure and Induce Diatom Deformities in Freshwater Biofilm Communities.pdf
Published 2021“…These antibiotics have been detected in all European surface waters with median concentrations of around 50 ng L<sup>–1</sup> and peak concentrations of up to 4–6 μg L<sup>–1</sup>. …”
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63308
<em>BRCA1</em> and <em>BRCA2</em> Missense Variants of High and Low Clinical Significance Influence Lymphoblastoid Cell Line Post-Irradiation Gene Expression
Published 2008“…Gaussian Process Classifier predicted <em>BRCA1</em>, <em>BRCA2</em> and <em>BRCAX</em> status, with a maximum of 62% accuracy, and prediction accuracy decreased with inclusion of <em>BRCAX</em> samples carrying an LCS variant, and inclusion of pathogenic missense carriers. …”
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63309
Data_Sheet_1_Impact of the COVID-19 Pandemic on the Effectiveness of a Metabolic Health Telemedicine Intervention for Weight Loss: A Propensity Score Matching Analysis.pdf
Published 2022“…</p>Results<p>Weight significantly decreased in both PC and Pre-PC at 3, 6, 9, and 12 months. …”
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63310
Data_Sheet_4_Bacteroides abundance drives birth mode dependent infant gut microbiota developmental trajectories.XLSX
Published 2022“…However, we did not observe an increase in functional alpha diversity, which was stable and comparable with the mother samples throughout all the sampling points. …”
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63311
Data Sheet 1_Past and future trends in swiss snow cover: multi-decades analysis using the snow observation from space algorithm.docx
Published 2025“…The pixel-wise analysis reveals significant negative trends in the monthly NDSI across all seasons, with the most pronounced decreases at low to mid-elevations, particularly in winter and spring (e.g., a 50% reduction in NDSI for pixels showing positive significative trends in winter below 1,000 m, and a 43% reduction in spring between 1,000 and 2,000 m). …”
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63312
Image 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”
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63313
Image_3_Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model.TIF
Published 2019“…Accordingly, lower virus replication, decreased presence in bronchioli and parenchyma and lower leukocytes and epithelial infected cells were found in the lungs of HA mut-infected animals. …”
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63314
The impact of a breast cancer diagnosis on health-related quality of life. A prospective comparison among middle-aged to elderly women with and without breast cancer
Published 2016“…</p> <p><b>Material and methods</b> The Danish Diet, Cancer and Health study included 57 053 cancer-free persons aged 50–64 years at baseline (1993–1997). We used data from first follow-up (1999–2002) and second follow-up (2010–2012) on HQoL [Medical Outcomes Survey, short form (SF-36)] obtained from 542 women aged 64–82 years with primary breast cancer (stages I–III) and a randomly matched sample of 729 women who remained breast cancer-free. …”
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63315
Image 3_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. A stark disparity remains, with low-SDI regions accounting for over 67% of deaths and DALYs. …”
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63316
Epidemiological consequences of repertoire population structure under high <i>var</i> gene diversity.
Published 2019“…We are interested in the comparison of the decreasing trends for the duration of infection across scenarios. …”
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63317
Table 2_Case Report: Acute generalized exanthematous pustulosis with psoriasis successfully treated with Secukinumab.docx
Published 2025“…Within a few days, a progressive eruption appeared and worsened until hospital admission with a baseline PASI score of 50.3 three weeks later. The rash was characterized by diffuse erythema, intense pruritus and severe desquamation. …”
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63318
Differences in Oxygen-Induced Retinopathy Susceptibility Between Two Sprague Dawley Rat Vendors: A Comparison of Retinal Transcriptomes
Published 2023“…Conversely, retinas from Envigo pups showed decreased necrosis and increased focal adhesion kinase signaling, supporting more normal vascular development. …”
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63319
Supplementary file 1_Past and future trends in swiss snow cover: multi-decades analysis using the snow observation from space algorithm.docx
Published 2025“…The pixel-wise analysis reveals significant negative trends in the monthly NDSI across all seasons, with the most pronounced decreases at low to mid-elevations, particularly in winter and spring (e.g., a 50% reduction in NDSI for pixels showing positive significative trends in winter below 1,000 m, and a 43% reduction in spring between 1,000 and 2,000 m). …”
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63320
Prevention of Obesity and Hyperlipidemia by Heptamethoxyflavone in High-fat Diet-induced Rats
Published 2019“…The supplementation of HMF not only significantly decreased body weight gain (HFD, 336.50 ± 18.84 g; LHMF, 309.43 ± 20.74 g; MHMF, 296.83 ± 13.88 g; HHMF, 265.71 ± 19.09 g; respectively, <i>p</i> < 0.05) and adipose tissues weight (<i>p</i> < 0.05), but also markedly lowered serum levels of total cholesterol, triacylglycerol, and low-density lipoprotein cholesterol (<i>p</i> < 0.05) in the sixth week in a dose-dependent manner compared with the HFD group. …”