Nur77 knockdown decreases cell viability and proliferation. by Alexa Tenga (2161780)

“…Cell confluence was averaged, with 4 replicates of each condition; *<i>p</i> < 0.0001. (D) Nur77 mRNA was significantly (<i>p</i> < 0.0001) decreased after transfecting Daoy cells with siNur77. …”

MPCs in aged myofibers display decreased myogenic activity. by Grégory Lacraz (370661)

Decreased spindle microtubules in CAMSAP2 KO cells. by Naoko Nishizawa (20536299)

Decreased mortality and weight in CHIP-T246M rodents. by Chang-he Shi (5315918)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Alcoholic Hepatitis Markedly Decreases the Capacity for Urea Synthesis by Emilie Glavind (3159438)

“…</p><p>Results</p><p>The FHNC was markedly decreased in the alcoholic hepatitis patients compared with the healthy controls (7.2±4.9 L/h vs. 37.4±6.8 L/h, P<0.01), and the largest decrease was observed in those with severe alcoholic hepatitis (4.9±3.6 L/h vs. 9.9±4.9 L/h, P<0.05). …”

Levels of Stt7 Decrease under Prolonged State 1 Conditions and High Light by Sylvain Lemeille (7986)

Argon-mediated decrease of apoptosis is attenuated following ERK1/2 and TLR inhibition. by Felix Ulbrich (678720)

(A) Adult male of <i>Brachycephalus ephippium</i> (Spix, 1824) (Photo: Pombal Jr., J.P.). (B) Fractionation of peptides from crude skin secretion of <i>B</i>. <i>ephippium</i>. by Daniel Dias Rufino Arcanjo (536744)

The role of the ER stress sensor IRE1 in ox-LDL-induced NO decrease in HCMECs. by Dan Hong (731836)

Depleted expression of ARTN in ER-MC cells decreases the angiogenic potential of HMEC-1 cells. by Arindam Banerjee (118618)

DPOAE responses are decreased one week after treatment with 8,000 mg/kg HPβCD. by Mark A. Crumling (107429)

TRAF6 and IRAK1 decrease hypoxia/reoxygenation-induced inflammatory responses in macrophages. by Weiwei Jiang (323409)

Infection of humanized mice resulted in decrease in pathogenicity in HTLV-1-CTCF infected mice. by Ancy Joseph (5634794)

hESCs-CM inhibited cell cycle progression of cancer cells and initiated a pro-apoptotic program. by Shufeng Zhou (398572)

Androgen and staurosporine synergize to decrease the relative ATP concentration in HPr-1AR cells. by Congcong Chen (796149)

“…In comparison to vehicle control, STS and to a lesser extent DHT significantly decrease the relative ATP concentration of HPr-1AR cells at 24 hours. …”

6a-P peptide decreases VEGF binding activity to cell surface by immunocytochemistry. by Tong-Young Lee (250877)

“…<p>Immunocytochemistry was used to confirm the FACS results. VEGF (0.1 µg/ml) binding intensity on HUVECS is decreased when the peptide (1 µg/ml) or VEGF-Trap (0.1 µg/ml) are present (A) (Bar, 20 µm). …”

CD107a-, IFNγ- and MIP 1β-producing Vγ9Vδ2 T-cell subsets decrease in HIV+ patients. by Rita Casetti (608635)

Different Association of Human Papillomavirus 16 Variants with Early and Late Presentation of Cervical Cancer by Ana Alfaro (280118)

“…Interestingly, when analyzing only the HPV16-positive CC, D2 increases (OR = 2.5, 95% CI = 1.2–5, p < 0.05) and D3 decreases (OR = 0.45, 95% CI 0.2–0.9, p < 0.05) the risk to develop CC before 50 years old in relation with A1/2 variant. …”