Decreased CD39 protein expression by islet resident macrophages heralds T1D in NOD mice. by Thomas B. Thornley (2550766)

Decreased HATL5 expression in esophageal and cervical carcinomas. by Gregory S. Miller (519005)

“…Staining intensities were determined as described in Material and Methods. (<b>A</b>) In esophageal squamous cell carcinomas, a highly significant decrease in staining intensity (P<0.0001) was observed between normal tissues and each of the two groups of cancer tissues; grades I-II and grade III, respectively. …”

The stimulation with FA or GW501516 decreases DNA damage. by Shota Tanaka (339198)

RyhB decreases Nuo and Sdh enzymatic activities. by Sylvia Chareyre (6619325)

DMB treatment decreased neuronal apoptosis in cerebral ischemia. by Huinan Zhang (849524)

Decreased pH is necessary and sufficient for intestinal hyperinflammation. by M. Kristina Hamilton (9162785)

An Increase in Presynaptic Density, but Not Efficacy, Induces a Decrease of Postsynaptic Dendritic Arbor Extension by Marco Tripodi (70526)

Coronavirus replication is decreased in AMPK-knockout (KO) cells. by Minsu Jang (2817730)

Nur77 knockdown decreases cell viability and proliferation. by Alexa Tenga (2161780)

“…Cell confluence was averaged, with 4 replicates of each condition; *<i>p</i> < 0.0001. (D) Nur77 mRNA was significantly (<i>p</i> < 0.0001) decreased after transfecting Daoy cells with siNur77. …”

MPCs in aged myofibers display decreased myogenic activity. by Grégory Lacraz (370661)

Decreased spindle microtubules in CAMSAP2 KO cells. by Naoko Nishizawa (20536299)

Decreased mortality and weight in CHIP-T246M rodents. by Chang-he Shi (5315918)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Targeting P-glycoprotein (ABCB1 or P-gp) has been recognized as a promising strategy to overcome multidrug resistance. Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Alcoholic Hepatitis Markedly Decreases the Capacity for Urea Synthesis by Emilie Glavind (3159438)

“…</p><p>Results</p><p>The FHNC was markedly decreased in the alcoholic hepatitis patients compared with the healthy controls (7.2±4.9 L/h vs. 37.4±6.8 L/h, P<0.01), and the largest decrease was observed in those with severe alcoholic hepatitis (4.9±3.6 L/h vs. 9.9±4.9 L/h, P<0.05). …”

Levels of Stt7 Decrease under Prolonged State 1 Conditions and High Light by Sylvain Lemeille (7986)

Argon-mediated decrease of apoptosis is attenuated following ERK1/2 and TLR inhibition. by Felix Ulbrich (678720)

(A) Adult male of <i>Brachycephalus ephippium</i> (Spix, 1824) (Photo: Pombal Jr., J.P.). (B) Fractionation of peptides from crude skin secretion of <i>B</i>. <i>ephippium</i>. by Daniel Dias Rufino Arcanjo (536744)

The role of the ER stress sensor IRE1 in ox-LDL-induced NO decrease in HCMECs. by Dan Hong (731836)

Depleted expression of ARTN in ER-MC cells decreases the angiogenic potential of HMEC-1 cells. by Arindam Banerjee (118618)