Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…Results are the mean ± SD of two independent experiments containing 8 replicates for each condition. * = <i>p</i><0.05, ** = <i>p</i><0.01, *** = <i>p</i><0.001, significant decrease compared to untreated cells (TA) or to siRNA Control (Kruskal & Wallis followed by Tukey and Dunnet test).…”

Effects of siRNA TMPRSS2-ERG on ERG protein expression and cell viability. by Giorgia Urbinati (554921)

“…MTT cell viability assay:</b> VCaP cells were transfected with siRNA TMPRSS2-ERG III (1, 2), TMPRSS2-ERG IV (1) and siRNA Control at 50 nM concentration and incubated for 72h. Bars represent mean ± SD of 2 independent experiments containing 8 replicates for each condition. …”

Effects of siRNA TMPRSS2-ERG III and IV on cell death pathways. by Giorgia Urbinati (554921)

Exposure to IQ3A compounds decreases <i>HSP90</i> and <i>KRAS</i> mRNA, protein expression and <i>KRAS</i> transcription. by Hugo Brito (747224)

CDDO-Me radioprotection decreases with progressive oncogenic manipulations in HBECs and in a matched NSCLC line. by Mariam El-Ashmawy (678638)

“…Mean ± SEM of three experiments seeded in triplicate, **p<0.01, t-test (compared to DMSO at 3 Gy).…”

Mean change in incidence and diagnoses if testing rates decrease. by Richard T. Gray (282417)

“…<p>Change in incidence (A) and diagnoses (B) if testing rates decrease by 30% and 50% relative to the current testing rate.…”

<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays. by Ling Tian (107492)

“…Error bars represented mean ± s.d. *p<0.05, **p<0.01, ***p<0.001 by unpaired two-tailed Student’s <i>t</i>-test.…”

A blue-shifted fluorescence donor increases fAP amplitude but exhibits a decreased SNR. A. by Ann E. Fink (312543)

<i>Vps13</i> mutant flies show a decreased life span, age dependent impairment of locomotor function and neurodegeneration. by Jan J. Vonk (3686662)

Effects of protein-bound uremic solutes on total glutathione level. by Takeo Edamatsu (4885138)

Decrease in blood pressure by PP2, a Src inhibitor in <i>Csk</i>^+/- mice. by Hyeon-Ju Lee (796527)

Reduced follicles, decreased ovulation and decreased fertilization of female Meox-2-cre/Separase S1121A mutant mice. by Juan Xu (225010)

Expression of Egln3 decreases tumor aggression, increases survival and normalizes glioma vascular architecture. by Vicki A. Sciorra (312082)

Capzb2 coimmunoprecipitates with βIII-tubulin in brain lysates and decreases tubulin polymerization in vitro. by David A. Davis (239142)

“…The average of 25 OD readings obtained for each of the Capzb2 concentrations examined was normalized against the average OD reading in the absence of Capzb2 during 750–1,500-s interval (darkly shaded in [E]) in which the final extent of tubulin polymerization is achieved for a given reaction. Capzb2 concentration is displayed on a log of 10 scale, so the first depicted point (tubulin polymerization in the absence of Capzb2; OD value = 100%) on the obtained nonlinear sigmoidal curve (<i>R</i>² = 0.99) corresponds to 0.01 on the Log Capzb2 (µM). …”

Decrease in intracellular lipid accumulation in 3T3-L1 cells by baicalein. by Yukari Nakao (3138795)

CNP decrease mitochondrial membrane potential and induce mitochondrial fragmentation in melanoma cells. by Elif Aplak (7430123)

“…<p>A, 300 μM CNP (4 h) significantly decreased mitochondrial membrane potential in A375 cells, but not in melanocytes, indicated by changes of TMRM dependent fluorescence in mitochondria. …”

Effects of bFGF on decrease of HG-induced accumulation of intracellular ROS levels. by Yuan Hu Xuan (632639)

Large amounts of ingested phenylpyruvate are required to decrease the survival of adult <i>A. gambiae</i> mosquitoes. by Silke Fuchs (506300)

Decreased oscillatory flow decreases <i>klf2a</i> expression. by Julien Vermot (257990)

“…*<i>p</i><0.05; **<i>p</i><0.01, ANOVA. (M) Outline summarizing the experimental outcome of decreasing oscillatory flow by decreasing heart rate. …”

Reduction of IL-8 is associated with a relevant decrease of GBA2 expression in CF bronchial cells. by Nicoletta Loberto (2224150)