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Downregulation of DOM decreases the abundance of PER and TIM.
Published 2019“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”
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MK-STYX decreases RhoA activation.
Published 2014“…Statistical analysis was performed using ANOVA (F<sub>3.9</sub> = 5.066, **p<0.01; *p<0.05). (<b>C</b>) PC12 cells transfected with MK-STYX, scrambled shRNA, or MK-STYX shRNA-A. 24 hr post-transfection cells were stimulated with NGF or not, and were lysed 24 hr thereafter and immunoblotted. …”
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PowerPoint Slides for: Patiromer Decreases Serum Potassium and Phosphate Levels in Patients on Hemodialysis
Published 2016“…Following P binder discontinuation, the long interdialytic interval mean ± SE serum P numerically increased from 5.8 ± 0.4 to 7.0 ± 0.5 mg/dl (p = 0.06). On patiromer, P decreased from 7.0 ± 0.5 to 6.2 ± 0.5 mg/dl (p = 0.04). …”
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LiCl administered via 0.5% LiCl food pellets for 4 wks decreases the antioxidant stress response.
Published 2015“…<p>(A) LiCl decreases <i>Nrf2</i> transcripts in hippocampus and cortex of R236H/+ mice (N = 5 male mice per group). …”
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OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts.
Published 2019“…After 4 weeks, when the tumor size was approximately 100 mm<sup>3</sup> (T<sub>0</sub>) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”
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