MyoF regulates the intracellular abundance of HTLV-1 Env. by Nicholas Polakowski (6894452)

“…Error bars show standard deviations; * <i>p</i><0.05, ** <i>p</i><0.01. <b>(D)</b> Knockdown of MyoF expression reduces levels of SU (gp46). …”

DataSheet_1_Probiotic effects on immunity and microbiome in HIV-1 discordant patients.docx by Carlos Blázquez-Bondia (14236472)

“…After washout, probiotic non-detection was also associated with a significant increase in CD4+ counts (457(153) vs. 416(142), median change = 45(75), counts/ml, p = 0.005) and CD4/CD8 ratio (0.67(0.5) vs 0.59(0.49), median change = 0.04 (0.18), p = 0.02).…”

DataSheet_2_Probiotic effects on immunity and microbiome in HIV-1 discordant patients.docx by Carlos Blázquez-Bondia (14236472)

“…After washout, probiotic non-detection was also associated with a significant increase in CD4+ counts (457(153) vs. 416(142), median change = 45(75), counts/ml, p = 0.005) and CD4/CD8 ratio (0.67(0.5) vs 0.59(0.49), median change = 0.04 (0.18), p = 0.02).…”

Differentially methylated regions interrogated for metastable epialleles associate with offspring adiposity by Stephanie W Waldrop (19653383)

“…Nine DMRs annotating to genes that annotated to MEs associated with change in offspring adiposity (false discovery rate <0.05). Methylation of approximately 80% of DMRs identified associated with decreased change in adiposity.…”

Mutations of SWI/SNF components and the small ribosomal subunit Rps2 result in elevated noise. by Shu-Ting You (140787)

“…Error bars represent standards errors. *<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001. Data associated with this figure can be found in the supplemental data file (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000433#pbio.3000433.s009" target="_blank">S1 Data</a>). …”

Restoration of normal division rates to <i>stat</i> mutant FSCs requires both excess G1/S and G2/M regulators. by David Melamed (565564)

“…SEMs and significant differences from control values are indicated (*, p<0.05, n-1 chi-squared test). All values derive from experiments where at least fifty ovarioles were scored. …”

Impact of moderate-to-severe ulcerative colitis and Crohn’s disease on sexual activity: United States and European patient perspectives from the communicating needs and features of... by Marla C. Dubinsky (10978320)

Analysis of the retrotransposition cycle in <i>nup</i> and <i>ulp1</i> mutants. by Amandine Bonnet (3411779)

“…The <i>spt3Δ</i> mutant is used as a control for qPCR specificity, as above. ns, not significant; * p<0.05; ** p<0.01; *** p<0.001, Welch’s t test with comparison to the WT strain.…”

A role for <i>bmm</i> in the regulation of sex differences in triglyceride homeostasis. by Lianna W. Wat (8339454)

“…Asterisks indicate a significant difference between two sexes, two genotypes, or two time points (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001). …”

<i>Rab23</i> deletion perturbs ciliation in a context-dependent manner. by Wan Ying Leong (22075947)

“…*<i><i>P</i></i> value 0.05. Unpaired Student’s t-test. <b>(J-K)</b> Representative immunocytochemistry images and <b>(K)</b> graph depicting quantification of the proportion of Arl13b+ (bottom panel green) primary cilia in the mouse embryonic fibroblasts cultured from E12.5 control and actin-CKO respectively. …”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…*<i>p</i>-value < 0.05 (chi-squared test with Yates’ continuity correction, <i>n</i> = 42 <i>Notch3</i>^<i>+/−</i><i>; Nodal</i>^{<i>flox/+</i>}<i>; n</i> = 76 <i>Hoxb1</i>^<i>Cre/+</i><i>; Nodal</i>^{<i>flox/null</i>} and 47 <i>Notch3</i>^<i>+/−</i><i>; Hoxb1</i>^{<i>Cre/+ </i>}<i>; Nodal</i>^{<i>flox/null</i>}). …”

The SMO pCT interacts with PKA-C. by Corvin D. Arveseth (10688311)

“…(<b>E</b>) HEK293 cells were infected with viruses encoding FLAG-tagged SMO674 or SMO566 and YFP-tagged PKA-C or Nbβ2AR80 and treated with increasing concentrations of DSP crosslinker (0, 0.125, 0.25, 0.5, 1, or 2 mM). Following DSP quenching, cell lysis, and FLAG purification of SMO complexes, purified samples were separated on reducing SDS-PAGE. …”

Metabolite analysis reveals elevated lactate and glucose metabolism in 5-day post-SE hippocampal metabolism—Signatures of Warburg metabolism. by Roaya S. Alqurashi (11243136)

“…Data are represented as mean ± SEM. *<i>P</i> <0.05, **<i>P</i> < 0.01 by unpaired student’s <i>t</i>-test using Prism 9.0 (Graphpad). …”

Male-biased effects of ubiquitous RNAi-mediated <i>bmm</i> inhibition reduces sex differences in triglyceride storage and breakdown. by Lianna W. Wat (8339454)

“…Asterisks indicate a significant difference between two sexes, two genotypes, or two time points (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001). …”

H2AK119ub is depleted from facultative heterochromatin as the cerebellum matures. by Aditya Parmar (22331873)

“…The significance threshold was a p-value <0.05, as computed using edgeR [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref071" target="_blank">71</a>] and limma [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref072" target="_blank">72</a>] (n = 4). …”

Neurodevelopmental H2AK119ub enrichment within H3K4me3-positive promoters subdues transcription. by Aditya Parmar (22331873)

“…The significance threshold was a p-value <0.05, as computed using edgeR and limma (n = 4). …”

SRMS accelerates ubiquitination of FKBP51 under nutrient-replete condition. by Jung Mi Park (5204840)

“…MDA-MB-231 cells were treated with 100 μg/mL cycloheximide in the presence of DMSO, 10 nM MG132, or 0.5 μM of ibrutinib for the indicated times. Lysates were immunoblotted with the indicated antibodies. …”

Cxcr4 promotes Cyclin D1 expression through ERK signaling during DFC proliferation. by Jingwen Liu (517390)

“…(G–H) WT embryos were treated with 0.5 μM PD0332991 or 0.2 μM CY202 from the shield stage to bud stage and then analyzed for L–R patterning defects at 48 hpf by in situ hybridizations with <i>cmlc2</i> and <i>hhex</i> probes. …”

Health system factors associated with unfavorable treatment outcomes in people with drug-susceptible TB (Gap 4). by Tulip A. Jhaveri (18625800)

Manipulation of PI3K/AKT signaling in α′β′ MBn affects HAB in sated state. by Meng-Hsuan Chiang (2794081)

“…Data were analyzed by one-way ANOVA followed by Tukey’s test. *<i>P</i> < 0.05.</p> <p>(TIF)</p>…”