pX interacts directly with the Bro1 domain of ALIX. by Takayoshi Shirasaki (10098660)

“…At the bottom is shown a quantitative analysis of Bro1 pulled down by biotin-tagged ExpD, normalized to pulldown in the absence of competitor peptide. Results shown are means ± s.e.m. from n = 3 independent experiments.…”

RAD51 protein and mRNA in NPC cells treated with Abexinostat combined with irradiation. by Mélanie Gressette (533795)

“…+IR). Protein extracts (20 µg/lane) were subjected to PAGE gel separation. …”

Rab2A regulates cellular lipid accumulation. by Zi-Yue Chen (11986539)

“…The data were analyzed with unpaired 2-tailed Student <i>t</i> test and are presented as the means ± s.e.m.s. “*” indicates <i>p</i> < 0.05. <b>(K)</b> Marked decreases in PPARγ-targeted genes were found in Rab2A-knockdown HepG2 cells. …”

STANDARDIZATION OF AN IN VITRO MODEL OF DIABETIC NEPHROPATHY IN RENAL TUBULAR CELLS AND INVESTIGATION OF THE ROLE OF ALDOSE REDUCTASE PATHWAY IN HIGH GLUCOSE-INDUCED RENAL CELL INJ... by El Gamal, Heba

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The point mutants E559A, E563A and K567A display altered DNA-binding kinetics. by Bettina Hüntelmann (566945)

“…The reactions were either left unchallenged (−) or challenged for 20 min with a 750-fold molar excess of a single, unlabelled GAS site (+ competition). …”

Gonococci enter macrophages despite a block in phagocytosis. by Stanimir S. Ivanov (3394922)

“…Inhibitors targeting: <b>(A)</b> actin polymerization (cytochalasin D, 5μM) and microtubules polymerization (nocodazole, 3μM); <b>(B)</b> the small GTPases Cdc42 (ML-141, 5μM), Rac1/2/3 (EHT 1864, 5μM) and the downstream effectors of Rho GTPase—LIMK1/2 kinases (BMS-5, 1μM) and ROCK1/2 kinases (GSK269962, 1μM); <b>(C)</b> the phagosome regulators Dynamin (dynasore, 30μM) and Phosphoinositide-3 kinase (LY294002, 10μM); <b>(D)</b> actin polymerization regulators formins (SMIFH2, 12.5 or 25μM), Arp2/3 complex (CK869, 10μM), Myosin II ATPases ((-) blebbistatin, from 2.5 to 20μM). <b>(E)</b> Decreased gonococci uptake at 8hpi by hMDMs treated with SMIFH2 as indicated. …”

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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Optimizing replay intensity and resolution in aberration-compensated off-axis holograms by ambient humidity control by Henry Nebrensky (1229277)

“…When a scene is located in water but the image is replayed into air it is necessary to correct for the refractive index </p><p>difference by reconstructing the image with shorter wavelength illumination and changing the beam angle to satisfy the grating equation. However this means that the Bragg condition may no longer be satisfied during replay, reducing the diffraction efficiency and decreasing the SNR of the reconstructed images. …”

YorkU.forest.Oct25-2016.csv by Andrew Laruffa (3116073)

“…The bowls were left there for 30 minutes from 3:20 to 3:50. After 30 minutes have elapsed, the number of insects in each bowl was counted.…”