On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues by Qian Wu (209382)

“…We evaluated electrospray deposition of liquid-phase derivatization agents as a means of on-tissue analyte derivatization using 2-picolylamine; we were able to detect a range of endogenous fatty acids with MALDI MSI. …”

Image_1_Transcranial direct current stimulation alters sensorimotor modulation during cognitive representation of movement.TIFF by Gaia Bonassi (12750008)

“…<p>We recently demonstrated, by means of short latency afferent inhibition (SAI), that before an imagined movement, during the reaction time (RT), SAI decreases only in the movement-related muscle (sensorimotor modulation) and that a correlation exists between sensorimotor modulation and motor imagery (MI) ability. …”

Doxycycline–induced expression of MTG16 altered gene expression. by Parveen Kumar (428921)

“…The levels of PFKFB3, PFKFB4 and PDK1 were decreased by doxycycline induction of MTG16.</p>…”

<i>Sassafras albidum</i> δ<i>¹³</i>C root data from trees labeled with 99% ¹³CO₂. by Thomas S. Adams (559029)

“…The age of the roots at the time of labeling did not significantly affect enrichment in any of the carbon pools in 2009 (<i>P_structural</i> = 0.15, <i>P_starch</i> = 0.26, <i>P_sugars</i> = 0.09).…”

Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium by Abbas Dehghan (174878)

“…Among an inception cohort of those who experienced MI during follow-up, the risk allele of rs1333049 was associated with a decreased risk of subsequent mortality (HR = 0.90, p-value = 3.2×10⁻³).…”

Pupil dilation and microsaccades provide complementary insights into the dynamics of arousal and instantaneous attention during effortful listening by Maria Chait (6765644)

“…The SNR between the noise and speech was initially set to 20dB, and was adjusted using a one-up-one-down adaptive procedure, tracking the 50% correct threshold. …”

Homologs of 16p12.1 genes contribute towards neurodevelopmental defects through weak genetic interactions and combined independent effects. by Lucilla Pizzo (2735491)

“…Simultaneous knockdown of <i>Cen</i>^{<i>GD9689</i>} with <i>UQCR-C2</i>^{<i>GD11238</i>} (n = 20, *p = 0.023) led to a milder suppression of the eye phenotype compared to knockdown of <i>Cen</i>^{<i>GD9689</i>} alone. …”

Comparison between empirical data and simulation results of FSIR and SIR models. by Ling Feng (283711)

“…The degree distribution is chosen at <i>P</i>(<i>k</i>) ∼ <i>k</i>^−2.5, <i>k</i>_<i>min</i> = 20 and ⟨<i>k</i>⟩ ≈ 50. With these parameters this distribution is close to the empirical distribution of OSNs. …”

Percentage of sequence coverage (significantly enriched regions) of core and accessory chromosomes with H3K4me2, H3K9me3 and H3K27me3 relative to the chromosome length. by Mareike Möller (5548745)

The average time cost and accuracy of the assessed secondary structure prediction methods as the sequence homology of the target dataset reduces. by Sheng-Hung Juan (9046515)

“…The lowest sequence identity was 25% because when a lower identity such as 20% was applied, the number of sequences remaining in the target dataset would be far smaller than the 5 million safety zone (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0235153#pone.0235153.g002" target="_blank">Fig 2</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0235153#pone.0235153.s016" target="_blank">S6 Table</a>) and then cause unreasonable decreases of the accuracy. …”

Olfactory interference: time course of the PER (A) and fitted ratio of survival rate (B). by Matthieu Dacher (269933)

“…Furthermore, the error bars increase in size when the number of animals still displaying a PER decreases at later time points, because the sample size is decreasing and the estimation of the ratio loses precision. …”

Autophagy drives fibroblast senescence through MTORC2 regulation by Monique Bernard (673834)

Data_Sheet_1_Climate and Human-Driven Variability of Summer Hypoxia on a Large River-Dominated Shelf as Revealed by a Hypoxia Index.docx by Kui Wang (137551)

“…In addition, warming of the bottom water from the Kuroshio Current accounts for an additional increasing rate for HI, which made hypoxia more severe by means of decreasing oxygen solubility. Overall, our results indicate that stratification, water residence and oxygen solubility resulting from climate change can explain about 80% while higher respiration resulting from higher nutrient inputs can explain about 20% of the variation in the severity of hypoxia during the past half century.…”

RMS-P3/RR phage binding correlates with furin expression levels. by Katarina Hajdin (249498)

“…Magnification: 40x; scale bars: 20 µm. (C) Inhibition of furin maturation in α1-PDX-transfected RD cells reduces phage binding. …”

Supplementary Material for: A Mixed-Method Study on Strategies in Everyday Personal Goals among Community-Dwelling Older Adults by Joly-Burra E. (9114362)

“…On the contrary, given that optimization is an anticipatory strategy to increase goal-relevant means in the absence of resource losses, we did not expect optimization to be related to either health or cognition. …”

Type 2 Diabetes Subgroups, Risk for Complications, and Differential Effects Due to an Intensive Lifestyle Intervention by Michael P. Bancks (10065295)

“…ILI focused on weight loss through decreased caloric intake and increased physical activity. …”

Antioxidant defense status tended to be lower in prediabetic GK/Par rat islets and was associated with enhanced reactive oxygen (ROS) production. by Grégory Lacraz (370661)

“…Intra-insular reduced glutathione (Eq GSH) content tended to be decreased in D7 GK/Par rats (<i>C</i>). ROS generation was assessed as fluorescence intensity (AU) normalized by total islet proteins in D7 Wistar or D7 GK/Par islets incubated for 30 min at 2.8 (G2.8) or 16.7 mmol/l glucose (G16.7), in the presence or the absence of blockers of the electron transfer chain complexes I (rotenone, 10 µmol/l) or III (antimycin A, 20 µmol/l), or the H₂O₂ scavenger (trolox, 1 mmol/l) (<i>D</i>). …”

Effects of Pyriproxyfen on Female Reproduction in the Common Cutworm, <i>Spodoptera litura</i> (F.) (Lepidoptera: Noctuidae) by Qi Xu (134661)

“…The use of pesticides remains the primary means for controlling <i>S</i>. <i>litura</i>, despite their negative ecological impact and potential threat to human health. …”

Effect of Epo on Beclin 1, LC3 and p62 expression in ileum of experimental NEC rats. by Yueyue Yu (437616)

“…Data are presented as means ± SD. * indicates <i>p</i><0.05 non-Epo treated group compared with MF group, # indicates <i>p</i><0.05 Epo treated group compared with non-Epo treated group by Student’s <i>t</i>-test. …”

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”