IPET and FETR: Experimental Approach for Studying Molecular Structure Dynamics by Cryo-Electron Tomography of a Single-Molecule Structure by Lei Zhang (38117)

“…Therefore, we developed a “focused electron tomography reconstruction” (FETR) algorithm to improve the resolution by decreasing the reconstructing image size so that it contains only a single-instance protein. …”

<b>Global patterns and drivers of soil dissolved organic carbon concentrations</b> by Andong Cai (10329365)

“…Elevation played the most important predictor for soil DOC prediction, followed by soil organic carbon, seasonal variability of temperature, and soil clay. Soil DOC decreases initially but increases when soil clay exceeds 20% and seasonal variability of temperature exceeds 0.7. …”

DataSheet_1_Ebosin Ameliorates Psoriasis-Like Inflammation of Mice via miR-155 Targeting tnfaip3 on IL-17 Pathway.docx by Weiwei Guo (117411)

“…Furthermore, we demonstrate that Ebosin significantly suppressed the IL-17 signaling pathway via A20 (encoded by tnfaip3) in vivo. …”

Nodes of Ranvier and Paranodes in Chronic Acquired Neuropathies by Carmen Cifuentes-Diaz (203836)

“…In CIAP paranodes, paranodin labeling was irregular and/or decreased. To test the consequences of acquired primary Schwann cells alteration on axonal proteins, we used a mouse model based on induced deletion of the transcription factor Krox-20 gene. …”

Altitudinal Patterns of Species Diversity and Phylogenetic Diversity across Temperate Mountain Forests of Northern China by Wenxin Zhang (112161)

“…We found that total species richness had a monotonically decreasing pattern and tree richness had a unimodal pattern along the elevation gradients in the two study areas. …”

Thyroid Hormone Regulation of Gene Expression in Primary Cerebrocortical Cells: Role of Thyroid Hormone Receptor Subtypes and Interactions with Retinoic Acid and Glucocorticoids by Pilar Gil-Ibáñez (533517)

“…In particular we focused on T3 receptor specificity, and on the crosstalk between T3, retinoic acid and dexamethasone. …”

Rapid Recovery of Visual Function Associated with Blue Cone Ablation in Zebrafish by Gordon F. Hagerman (3366290)

“…This visually mediated behaviour decreased to about 5% or 20% of control levels following ablation of UV or blue cones, respectively (P<0.05). …”

Table_1_Exogenous Melatonin Directly and Indirectly Influences Sheep Oocytes.docx by Yang Chen (9737)

“…One study found that the blastocyst rate increased under MT treatment, while another found that the blastocyst rate decreased. Therefore, we conducted a meta-analysis of MT directly and indirectly influencing sheep oocytes. …”

Prediction of 30-day pediatric unplanned hospitalizations using the Johns Hopkins Adjusted Clinical Groups risk adjustment system by Mitchell G. Maltenfort (7252064)

“…Applying these coefficients to a 30% test sample to generate risk scores, we found that the area under the receiver operator characteristic curve (AUC) was 0.82. …”

Data_Sheet_1_Tandem Mass Tagging Based Identification of Proteome Signatures for Reductive Stress Cardiomyopathy.pdf by Sini Sunny (12864302)

“…Interestingly, proteins that were involved in mitochondrial respiration, lipophagy and cardiac rhythm were dramatically decreased in TG hearts. Of note, we identified the glutathione family of proteins as the significantly changed subset of the proteome in TG heart. …”

DataSheet1_Avasimibe Alleviates Disruption of the Airway Epithelial Barrier by Suppressing the Wnt/β-Catenin Signaling Pathway.PDF by Zicong Zhou (12075644)

“…However, its efficacy in asthma has not yet been reported. We first administered varying concentrations of avasimibe to house dust mite (HDM)-induced asthmatic mice; results showed that 20 mg/kg avasimibe most significantly reduced IL-4 and IL-5 production in bronchoalveolar lavage fluid (BALF) and total IgE in serum, and the avasimibe treatment also exhibited lower mucus secretion, decreased goblet and basal cells but increased ciliated cells compared to the HDM group. …”

Table_2_Comprehensive Transcriptome Analysis Reveals Competing Endogenous RNA Networks During Avian Leukosis Virus, Subgroup J-Induced Tumorigenesis in Chickens.XLS by Lingling Qiu (2591032)

“…High-throughput sequencing followed by quantitative real-time polymerase chain reaction and bioinformatics analyses were performed to advance the understanding of regulatory networks associated with differentially expressed non-coding RNAs and mRNAs that facilitate ALV-J infection. We examined the expression of mRNAs, long non-coding RNAs (lncRNAs), and miRNAs in the spleens of 20-week-old chickens infected with ALV-J and uninfected chickens. …”

Image_2_Tandem Mass Tagging Based Identification of Proteome Signatures for Reductive Stress Cardiomyopathy.pdf by Sini Sunny (12864302)

“…Interestingly, proteins that were involved in mitochondrial respiration, lipophagy and cardiac rhythm were dramatically decreased in TG hearts. Of note, we identified the glutathione family of proteins as the significantly changed subset of the proteome in TG heart. …”

How is Herstatin, a tumor suppressor splice variant of the oncogene <i>HER2</i>, regulated? by Marco Silipo (3388997)

“…<p>The human epidermal growth factor receptor 2 (HER2)/receptor tyrosine-protein kinasebB-2 (ERBB2) is overexpressed in 20–30% of breast tumors leading to faster growing and more aggressive tumors. …”

Table_1_Uncertainty in coprophilous fungal spore concentration estimates.DOCX by Angelina G. Perrotti (14292716)

“…Prior work has encouraged reporting CFS abundances as accumulation rates (spores/unit²/year) or concentration (spores/unit³) instead of percentages relative to the total pollen abundance, because CFS percentages can be sensitive to fluctuations in pollen influx. In this work, we quantify the uncertainty associated with estimating concentration values at different total counts and find that high uncertainty is associated with concentration estimates using low to moderate total counts (n = 20 to 200) of individual fungal spore types and tracers. …”

Table_1_Photobiomodulation of Cytochrome c Oxidase by Chronic Transcranial Laser in Young and Aged Brains.docx by Fabrízio dos Santos Cardoso (12259052)

“…We found that aging predominantly decreased regional brain CCO activity and systems-level functional connectivity, while the chronic laser stimulation predominantly reversed these age-related effects. …”

Supplementary Material for: The EFEMP1 Gene: A Frequent Target for Epigenetic Silencing in Multiple Human Pituitary Adenoma Subtypes by Duong C.V. (3835249)

“…<b><i>Methods:</i></b> In an independent cohort we determined expression of EFEMP1, CpG island methylation and histone tail modification status. …”

Data_Sheet_1_Sexually Distinct Song Cultures Across a Songbird Metapopulation.zip by Wesley H. Webb (11717369)

“…Having classified 20,700 syllables (702 types), we compare population syllable repertoire sizes and overlap between sites and sexes. …”

Table_1_Uncertainty in coprophilous fungal spore concentration estimates.DOCX by Angelina G. Perrotti (14292716)

“…Prior work has encouraged reporting CFS abundances as accumulation rates (spores/unit²/year) or concentration (spores/unit³) instead of percentages relative to the total pollen abundance, because CFS percentages can be sensitive to fluctuations in pollen influx. In this work, we quantify the uncertainty associated with estimating concentration values at different total counts and find that high uncertainty is associated with concentration estimates using low to moderate total counts (n = 20 to 200) of individual fungal spore types and tracers. …”

Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways by Jane Palsgaard (261012)

“…<em>LDHB</em> was found to have a decreased expression in both groups compared to controls.…”