Vpr influences the expression level of GRP78 and Mfn2 proteins. by Chih-Yang Huang (54970)

Expression changes of HIF and ATF4 modulated by miR-205. by Shiyo Muratsu-Ikeda (313491)

Reinforced Ross Procedure in an Adult "Beating Heart Autograft Harvest" by Sameh M. Said (8697503)

(A) Rate of mature forest loss at each time interval, estimated from single-date image classification by M E Fagan (557038)

“…</strong> (A) Rate of mature forest loss at each time interval, estimated from single-date image classification. The mean rates of forest loss declined from 2.20% yr⁻¹ pre-ban (1986–1996) to −1.38% yr⁻¹ post-ban (1996–2011). …”

Supplementary file 1_Spatiotemporal monitoring in beidagang wetland using Landsat time-series images and Google Earth Engine during 2000–2022.docx by Xinyue Zhang (271120)

“…Interannual dynamics during 2000–2022 revealed two distinct periods: terrestrial vegetation (TerV) dominance with permanent water (PW) below 10% (2000–2014), and PW exceeding 20% while temporary vegetation (TemV) decreased (2015–2022). …”

Table_1_Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm.docx by Ji Chen (69329)

Myopia Progression during the COVID-19 Era: A Systematic Review and Meta-analysis by Mohammad Javad Najafzadeh (8873153)

“…Mean screen time was increased 6.25 hours/day (95% CI, 4.84–7.66), and outdoor activity time was decreased −1.52 hours/day (95% CI, −3.20 to −0.15).…”

Sustained Attention is Associated with Error Processing Impairment: Evidence from Mental Fatigue Study in Four-Choice Reaction Time Task by Yi Xiao (135101)

“…Event-related potential results showed that ERN (p < 0.005) and peak (p < 0.05) mean amplitudes decreased in the fatigue experiment. …”

Effects of lixisenatide versus liraglutide (short- and long-acting GLP-1 receptor agonists) on esophageal and gastric function in patients with type 2 diabetes by Daniel R. Quast (8980434)

“…No significant changes from baseline in other parameters of esophageal motility and lower esophageal sphincter function were observed. Gastric acidity decreased significantly by -20.7 (-40.6, -0.8) % (p = 0.042) with the GLP-1 RAs.…”

Mitochondria structure and function in the rat hearts. by Ming Zhang (9736)

The JNK pathway regulates <i>upd3</i> expression in haemocytes. by Sveta Chakrabarti (634821)

MicroRNA-138 improves LPS-induced trophoblast dysfunction through targeting RELA and NF-κB signaling by Ailan Yin (10110696)

“…Although NF-κB and proinflammatory cytokines have been reported to be related to trophoblast dysfunction, the underlying mechanism remains unclear. Herein, we demonstrated the miR-138/RELA axis modulating the migratory ability, and invasive ability of HTR-8/SVneo and JEG-3 cells, as well as the inflammatory factor levels in response to LPS stimulation. miR-138 expression was upregulated in preeclampsia placenta and LPS-stimulated HTR-8/SVneo and JEG-3 cell lines. miR-138 overexpression rescued the migratory and invasive ability of HTR-8/SVneo and JEG-3 cells inhibited by LPS stimulation, and decreased LPS-induced TNF-α and IL-6 levels. …”

Effects of BMAL activator level on circadian oscillations in a stochastic model of isolated cellular oscillators. by Caroline H. Ko (240081)

“…These results show that as the percentage of total BMAL decreases, the mean period length decreases, along with an increase in the variance of the period. …”

Displacement vectors between the perturbed and initial structures of ferric-binding protein. by Canan Atilgan (257960)

Across Chub-S7 differentiation, total ACC (a) and AMPK (b) levels increase. by Laura L. Gathercole (341979)

Image1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Table1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.docx by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Image3_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Image2_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Introduction<p>Monoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol-2-yl) propanal oxime) that is currently under clinical development for neuropathic pain and characterized the mouse model through complex functional, in vivo imaging, and morphological techniques.…”

Interventions performed to maintain vital parameters within preset limits. by Paul Skorup (289783)