DataSheet_1_The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass.docx by Tuo Pan (9264234)

“…</p>Results<p>In propensity-matched patients, the 30-day mortality (16% vs 24%, P=0.32), stroke (2% vs 8%, P=0.17), ECMO(6% vs 10%, P=0.46), IABP(4% vs 8%, P=0.40) and CRRT(8% vs 20%, P=0.08) had no differences between sivelestat and control group; sivelestat could significantly decrease pneumonia (40% vs 62%, P=0.03), mechanical ventilation time (median: 96hours, IQR:72-120hours vs median:148hours, IQR:110-186hours, P<0.01), bilateral pulmonary infiltrates (P<0.01), oxygen index (P<0.01), interleukin-6(P=0.02), procalcitonin(P<0.01) and C-reactive protein(P<0.01).…”

Image2_Maternal nano-titanium dioxide inhalation alters fetoplacental outcomes in a sexually dimorphic manner.jpg by Julie A. Griffith (12215116)

“…Exposures to toxicant such as diesel exhaust, have been shown to result in sexually dimorphic outcomes like decreased placental mass in exposed females. Therefore, we hypothesize that maternal nano-TiO₂ inhalation exposure during gestation alters placental hemodynamics in a sexually dimorphic manner. …”

Data_Sheet_2_The Effect of Pet Insurance on Presurgical Euthanasia of Dogs With Gastric Dilatation-Volvulus: A Novel Approach to Quantifying Economic Euthanasia in Veterinary Emerg... by Manuel Boller (6823733)

“…Thus, insurance was associated with a marked decrease in risk of pre-surgical euthanasia indicating that the cause of pre-surgical euthanasia of dogs with GDV is predominantly economic in nature. …”

Image1_Maternal nano-titanium dioxide inhalation alters fetoplacental outcomes in a sexually dimorphic manner.JPEG by Julie A. Griffith (12215116)

“…Exposures to toxicant such as diesel exhaust, have been shown to result in sexually dimorphic outcomes like decreased placental mass in exposed females. Therefore, we hypothesize that maternal nano-TiO₂ inhalation exposure during gestation alters placental hemodynamics in a sexually dimorphic manner. …”

Table_2_Clinical and economic impact of coronary artery bypass graft and percutaneous coronary intervention in young individuals with acute coronary syndromes and multivessel disea... by Gustavo de Almeida Alexim (14097072)

“…</p>Results<p>Among 1,088 subjects (111 CABG and 977 PCI) followed for 6.2 years (IQR: 1.1), 304 primary events were observed. MACE was observed in 20.7% of the CABG group and 28.8% of the PCI group (p = 0.037). …”

Table_1_Clinical and economic impact of coronary artery bypass graft and percutaneous coronary intervention in young individuals with acute coronary syndromes and multivessel disea... by Gustavo de Almeida Alexim (14097072)

“…</p>Results<p>Among 1,088 subjects (111 CABG and 977 PCI) followed for 6.2 years (IQR: 1.1), 304 primary events were observed. MACE was observed in 20.7% of the CABG group and 28.8% of the PCI group (p = 0.037). …”

Data_Sheet_1_Isolation and identification of ligninolytic bacterium (Bacillus cereus) from buffalo (Bubalus bubalis) rumen and its effects on the fermentation quality, nutrient com... by Huimin Zhong (6847475)

“…It exhibited a lignin-degradation rate of 20.5% after being inoculated in a lignin-degrading medium for 8 days. …”

Alterations in the vitamin D endocrine system during pregnancy: A longitudinal study of 855 healthy Norwegian women by Miriam K. Gustafsson (5089163)

“…A decrease in 1,25(OH)₂D occurred in 45% of those with vitamin D deficiency, and they also exhibited lower levels than women with adequate vitamin D status. …”

Mesenchymal stromal cells (MSCs) induce <i>ex vivo</i> proliferation and erythroid commitment of cord blood haematopoietic stem cells (CB-CD34+ cells) by Simone Perucca (3775696)

“…In the presence of MSCs, a significant increase in CD34+ cell number was observed (fold increase = 14.68), mostly in the SN-fraction (fold increase = 13.20). This was combined with a significant increase in CD34+ cell differentiation towards the BFU-E colonies and with a decrease in the CFU-GM. …”

Carbon-Coated Iron Oxide Nanoparticles Promote Reductive Stress-Mediated Cytotoxic Autophagy in Drug-Induced Senescent Breast Cancer Cells by Anna Lewińska (8932991)

“…In the present study, Fe₃O₄ NPs <i>in situ</i> coated by dextran (Fe₃O₄@Dex) and glucosamine-based amorphous carbon coating (Fe₃O₄@aC) with potent reductive activity were characterized and tested against drug-induced senescent breast cancer cells (Hs 578T, BT-20, MDA-MB-468, and MDA-MB-175-VII cells). Fe₃O₄@aC caused a decrease in reactive oxygen species (ROS) production and an increase in the levels of antioxidant proteins FOXO3a, SOD1, and GPX4 that was accompanied by elevated levels of cell cycle inhibitors (p21, p27, and p57), proinflammatory (NFκB, IL-6, and IL-8) and autophagic (BECN1, LC3B) markers, nucleolar stress, and subsequent apoptotic cell death in etoposide-stimulated senescent breast cancer cells. …”

DataSheet_1_Paradise by the far-red light: Far-red and red:blue ratios independently affect yield, pigments, and carbohydrate production in lettuce, Lactuca sativa.docx by Jordan B. Van Brenk (18466467)

“…White light with and without FR (W and W+FR) were used as control treatments comprising of 72.5% red, 19% green, and 8.5% blue light. Decreasing the R:B ratio from R:B_87.5:12.5 to R:B_60:40, there was a decrease in fresh weight (20%) and carbohydrate concentration (48% reduction in both sugars and starch), whereas pigment concentrations (anthocyanins, chlorophyll, and carotenoids), phenolic compounds, and various minerals all increased. …”

DataSheet_1_Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy.pdf by Brigida Boccanegra (11104155)

“…</p>Results<p>In vivo, both GHSs increased mice forelimb force (recovery score, RS towards WT: 20% for EP80317 and 32% for JMV2894 at week 8). …”

DataSheet_1_The neutrophil elastase inhibitor, sivelestat, attenuates acute lung injury in patients with cardiopulmonary bypass.docx by Tuo Pan (9264234)

“…</p>Results<p>In propensity-matched patients, the 30-day mortality (16% vs 24%, P=0.32), stroke (2% vs 8%, P=0.17), ECMO(6% vs 10%, P=0.46), IABP(4% vs 8%, P=0.40) and CRRT(8% vs 20%, P=0.08) had no differences between sivelestat and control group; sivelestat could significantly decrease pneumonia (40% vs 62%, P=0.03), mechanical ventilation time (median: 96hours, IQR:72-120hours vs median:148hours, IQR:110-186hours, P<0.01), bilateral pulmonary infiltrates (P<0.01), oxygen index (P<0.01), interleukin-6(P=0.02), procalcitonin(P<0.01) and C-reactive protein(P<0.01).…”

Data_Sheet_1_The Effect of Pet Insurance on Presurgical Euthanasia of Dogs With Gastric Dilatation-Volvulus: A Novel Approach to Quantifying Economic Euthanasia in Veterinary Emerg... by Manuel Boller (6823733)

“…Thus, insurance was associated with a marked decrease in risk of pre-surgical euthanasia indicating that the cause of pre-surgical euthanasia of dogs with GDV is predominantly economic in nature. …”

Table_1_Efficacy of insulin in treating severe hypertriglyceridaemia in the third trimester of pregnancy.docx by Dong Zhou (313567)

“…General maternal information, delivery, perinatal treatment and laboratory examination information were collected from electronic medical records and compared. We found that in the insulin treatment group, there were higher values of progestational body mass index (BMI) (Z = −2.281, P = 0.023), higher incidence of diabetes (χ² = 20.618, P < 0.001) and higher incidence of fatty liver (χ² = 4.333, P = 0.037) than in the control group but also a higher pregnancy weight gain compliance rate (χ² = 4.061, P = 0.044). …”

DataSheet_1_Histidine-rich glycoprotein in metabolic dysfunction-associated steatohepatitis-related disease progression and liver carcinogenesis.pdf by Beatrice Foglia (3804862)

“…Here we investigated the role of histidine-rich glycoprotein (HRG), a plasma protein produced by hepatocytes, in MASLD/MASH progression and HCC development.…”

Dietary sodium butyrate improves intestinal development and function by modulating the microbial community in broilers by Wei Wu (27708)

“…SB additions at 400 mg/kg displayed higher <i>Firmicutes</i> and <i>Proteobacteria</i> levels, while a higher (<i>P</i><0.05) relative abundance of <i>Bacteroidetes</i> was observed at 800 mg/kg. Furthermore, we found a striking decrease in <i>Enterobacteriaceae</i> and increases in <i>Lachnospiraceae</i> and <i>Rikenellaceae</i> in the cecal lumen of birds fed 800 mg/kg SB as well as a higher proportion of <i>Ruminococcaceae</i> and a noticeable reduction (<i>P</i><0.05) of <i>Lactobacillaceae</i> in birds treated with 400 mg/kg SB. …”

iNTS_QECH_2011-2019_aggregate_age.docx by Catherine Wilson (8586315)

“…Here we provide updated surveillance data on invasive non-typhoidal <i>Salmonella</i> disease from 2011 – 2019.…”

Data_Sheet_1_One vaccine to counter many diseases? Modeling the economics of oral polio vaccine against child mortality and COVID-19.docx by Angela Y. Chang (1759720)

“…</p>Materials and methods<p>We studied two settings: (1) reducing child mortality in a high-mortality setting (Guinea-Bissau) and (2) preventing COVID-19 in India. …”

Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics by Nomikos, Michail

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