table1_Development and Validation of an Interleukin-6 Nomogram to Predict Primary Non-response to Infliximab in Crohn’s Disease Patients.docx by Yueying Chen (8708796)

“…<p>Background: The primary non-response (PNR) rate of infliximab (IFX) varies from 20 to 46% for the treatment of Crohn’s disease (CD). …”

Video_1_The TRPV4 Agonist GSK1016790A Regulates the Membrane Expression of TRPV4 Channels.mp4 by Sara Baratchi (357850)

“…Single molecule analysis of TRPV4 channels showed that the density of TRPV4 at the plasma membrane is controlled through two modes of membrane trafficking, complete, and partial vesicular fusion. Further, we show that the density of TRPV4 at the plasma membrane decreased within 20 min, as they translocate to the recycling endosomes and that the surface density is dependent on the release of calcium from the intracellular stores and is controlled via a PI3K, PKC, and RhoA signaling pathway.…”

Table_9_More Hype Than Substance? A Meta-Analysis on Job and Task Rotation.pdf by Lisa Mlekus (10431668)

“…Due to a conceptual overlap and frequent confusion of terminology, we analyzed the design of the rotation (job rotation vs. task rotation) as a possible moderator. …”

Supplementary Material for: Therapy patterns and surveillance measures of Inflammatory Bowel Disease patients beyond disease-related hospitalization: a claims-based cohort study by Baehler C. (12466698)

“…During the 1-year follow-up, 20.5% of all IBD patients had no diagnostic or disease-monitoring procedure. …”

Image1_Development and Validation of an Interleukin-6 Nomogram to Predict Primary Non-response to Infliximab in Crohn’s Disease Patients.tif by Yueying Chen (8708796)

“…<p>Background: The primary non-response (PNR) rate of infliximab (IFX) varies from 20 to 46% for the treatment of Crohn’s disease (CD). …”

Multiplexed Protease Activity Assay for Low-Volume Clinical Samples Using Droplet-Based Microfluidics and Its Application to Endometriosis by Chia-Hung Chen (504554)

“…However, multiple proteases and endogenous inhibitors interact to govern MP activity, often leading to highly context-dependent protease function that unfortunately has impeded associated clinical utility. We present a method for rapidly assessing the activity of multiple specific proteases in small volumes (<20 μL) of complex biological fluids such as clinical samples that are available only in very limited amounts. …”

Table1_SVInterpreter: A Comprehensive Topologically Associated Domain-Based Clinical Outcome Prediction Tool for Balanced and Unbalanced Structural Variants.PDF by Joana Fino (3182070)

“…Among others, gene-associated data (as function and dosage sensitivity), phenotype similarity scores, and copy number variants (CNVs) scoring metrics are retrieved for an informed SV interpretation. For evaluation, we retrospectively applied SVInterpreter to 97 balanced (translocations and inversions) and 125 unbalanced (deletions, duplications, and insertions) previously published SVs, and 145 SVs identified from 20 clinical samples. …”

On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues by Qian Wu (209382)

“…On-tissue analyte derivatization addresses these issues by selectively tagging functional groups specific to a class of analytes, while simultaneously changing their molecular masses and improving their desorption and ionization efficiency. We evaluated electrospray deposition of liquid-phase derivatization agents as a means of on-tissue analyte derivatization using 2-picolylamine; we were able to detect a range of endogenous fatty acids with MALDI MSI. …”

table2_Development and Validation of an Interleukin-6 Nomogram to Predict Primary Non-response to Infliximab in Crohn’s Disease Patients.docx by Yueying Chen (8708796)

“…<p>Background: The primary non-response (PNR) rate of infliximab (IFX) varies from 20 to 46% for the treatment of Crohn’s disease (CD). …”

Table5_SVInterpreter: A Comprehensive Topologically Associated Domain-Based Clinical Outcome Prediction Tool for Balanced and Unbalanced Structural Variants.xlsx by Joana Fino (3182070)

“…Among others, gene-associated data (as function and dosage sensitivity), phenotype similarity scores, and copy number variants (CNVs) scoring metrics are retrieved for an informed SV interpretation. For evaluation, we retrospectively applied SVInterpreter to 97 balanced (translocations and inversions) and 125 unbalanced (deletions, duplications, and insertions) previously published SVs, and 145 SVs identified from 20 clinical samples. …”

Multiplexed Protease Activity Assay for Low-Volume Clinical Samples Using Droplet-Based Microfluidics and Its Application to Endometriosis by Chia-Hung Chen (504554)

“…However, multiple proteases and endogenous inhibitors interact to govern MP activity, often leading to highly context-dependent protease function that unfortunately has impeded associated clinical utility. We present a method for rapidly assessing the activity of multiple specific proteases in small volumes (<20 μL) of complex biological fluids such as clinical samples that are available only in very limited amounts. …”

Image_2_Subchronic Toxicity of Microcystin-LR on Young Frogs (Xenopus laevis) and Their Gut Microbiota.TIF by Jinjin Li (849002)

“…MC-LR significantly decreased the activities of malondialdehyde and alkaline phosphatase and the expression of TGF-β in the liver. …”

Image_1_Transcranial direct current stimulation alters sensorimotor modulation during cognitive representation of movement.TIFF by Gaia Bonassi (12750008)

“…<p>We recently demonstrated, by means of short latency afferent inhibition (SAI), that before an imagined movement, during the reaction time (RT), SAI decreases only in the movement-related muscle (sensorimotor modulation) and that a correlation exists between sensorimotor modulation and motor imagery (MI) ability. …”

DataSheet_1_Targeting WEE1 Inhibits Growth of Breast Cancer Cells That Are Resistant to Endocrine Therapy and CDK4/6 Inhibitors.pdf by Yassi Fallah (7121720)

“…ER+ tumors that progress on antiestrogens are treated with antiestrogens and CDK4/6 inhibitors. However, 20% of these tumors never respond to CDK4/6 inhibitors due to intrinsic resistance. …”

Data_Sheet_3_Disease activity in primary progressive multiple sclerosis: a systematic review and meta-analysis.docx by Katelijn M. Blok (17339695)

“…</p>Results<p>We included 34 articles describing 7,109 people with PPMS (pwPPMS). …”

DataSheet_1_Long-term changes in bloom dynamics of Southern and Central Baltic cold-water phytoplankton.docx by Carolin Paul (741757)

“…In contrast, biomass dynamics of the dinoflagellate P. catenata are more independent from these factors but have decreased strongly since the beginning of the 21^st century. …”

Proteomic and Phosphoproteomic Changes Induced by Prolonged Activation of Human Eosinophils with IL‑3 by Stephane Esnault (24104)

“…To characterize this phenotype, we quantified protein abundance and phosphorylation by multiplexed isobaric labeling combined with high-resolution mass spectrometry. …”

The differences in homeostasis model assessment values in type 2 diabetic patients with different lengths of history of diabetes by Chen Wang (88408)

“…HOMA-IR in patients with a history of diabetes of between 20 and 30 years was lower than that in other diabetic patients (p < 0.05). …”

Table_1_Subchronic Toxicity of Microcystin-LR on Young Frogs (Xenopus laevis) and Their Gut Microbiota.XLSX by Jinjin Li (849002)

“…MC-LR significantly decreased the activities of malondialdehyde and alkaline phosphatase and the expression of TGF-β in the liver. …”

Image_2_Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration.tif by Zhenggang Zhang (3161334)

“…In contrast, allografts ST2 deficiency resulted in decreased infiltration of F4/80⁺ macrophages, CD3⁺ T cells and CD20⁺ B cells and thus alleviated vascular occlusion and fibrosis of allografts. …”