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642
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Published 2020“…MYBPC3 variants genotype–phenotype associations remain poorly understood. We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …”
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643
Toxic Effect Of Lannate On Cellular Defence System In Erythrocyte Of Rat
Published 1996“…It has been observed that there was a decrease in the activities of superoxide dismutase and glutathione reductase after 1/2 and 16 hour of Lannate addition. …”
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644
Empower Generations: Longitudinal Study for National Capacities in Life Sciences and Healthcare
Published 2021“…However, the association between a history of EG training and the university’s GPA is significant, with a p < 0.001, OR 5.016 (2.954–8.518). …”
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645
Ocean Acidification and Carbonate System Geochemistry in the Arabian Gulf
Published 2020“…NAlk and NDIC decrease corresponding to a CaCO3/OrgC removal ratio of 2/1. …”
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646
The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio...
Published 2016“…Class IV hemorrhagic shock caused differential arteriole responses with vasoconstriction from baseline of A1 and A2 ( − 22.1 ± 1.9%), and vasodilation of the A3 and A4 arterioles (+22.2 ± 2.8%). …”
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647
Synthesis and properties of HA/ZnO/CNT nanocomposite
Published 2018“…The goal of this study was to examine the tribomechanical properties of hydroxyapatite (HA)/ZnO and HA/ZnO/CNT composite ceramics (carbon nanotubes; with different ratios 0.5 wt%, 1.0 wt%, and 1.5 wt%). The composites were synthesized using the hydrothermal method in an autoclave. …”
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648
EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS
Published 2016“…Methodology: In the present study, utilizing the HRMEC, we evaluated the effect of high glucose (30mM) on several ER stress signaling pathway genes (HSPA5, EIF2K3, and XBP1) at the mRNA expression level; the inflammatory cytokines (NFkB) at the mRNA level; the adhesion molecules (ICAM-1 and P-selectin) by flow cytometry. …”
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649
Hydrogen Production via Ethanol Decomposition over Bimetallic Catalyst
Published 2016“…At higher value of φ, the reactive medium generates H2 rich reducing environment to convert metal oxide to metallic form Bimetallic CuCo were synthesized from the aqueous solution of cobalt nitrate (Co(NO3)2·6H2O), copper nitrate (Cu(NO3)2·6H2O) and glycine (C2H5NO2) in solution combustion synthesis (SCS) method using a fuel to oxidizer ratio of φ 0.5, 1, 1.75 and 2.5. …”
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650
Flexible impedance and capacitive tensile load Sensor based on CNT composite
Published 2016“…The increase in impedance of the cells is observed to be 2.0 times while the decrease in the capacitance is found to be 2.1 times as applied force increases up to 0.3 N. …”
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651
Isothermal crystallization kinetics and morphology of double crystalline PCL/PBS blends mixed with a polycarbonate/MWCNTs masterbatch
Published 2019“…For the nanocomposites, there was a decrease in Tc values. This was attributed to a competition between two effects: (1) The partial miscibility of the PC-rich and the PCL-rich and PBS-rich phases, and (2) the nucleation effect of the MWCNTs. …”
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652
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
Published 2024“…In the same period, PUV increased in central Europe, eastern Europe, and central Asia by 116·1% (8·0–218·2). Our forecasts predict a continued global decline in HIV incidence and mortality, with the number of people living with HIV peaking at 44·4 million (40·7–49·8) by 2039, followed by a gradual decrease. …”
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653
Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes
Published 2012“…Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. …”
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654
Barriers and Motivators of Appropriate Antibiotic Prescription at PHCC in Qatar: Perspective of Physicians and Pharmacists
Published 2020“…Data were collected from 50 participants across two PHCCs; 30 physicians and 20 pharmacists. Two different interview guides were constructed; one for physicians and one for pharmacists. …”
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655
Barriers and motivators of appropriate antibiotic prescription at PHCC in Qatar: perspective of physicians and pharmacists
Published 2020“…Data were collected from 50 participants across two PHCCs; 30 physicians and 20 pharmacists. Two different interview guides were constructed; one for physicians and one for pharmacists. …”
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656
Conversion of Organic Municipal Wastes into Biochars and their Effect on Fertility Parameters of Normal and Sabkha Soils of Qatar
Published 2016“…To each pot, sufficient amount of 0.25-mm sieved biochar was mixed with soil to yield carbon to soil ratios of 0, 1, and 2% (wt/wt). Box-Behnken experimental design was used instead of the full factorial to decrease the number of treatments to a manageable level (126 treatments) with three replications at the center. …”
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657
A thermodynamic study of propanol reforming in presence of hydrazine for hydrogen production
Published 2021“…Steam reforming of propanol displayed higher hydrogen production and a gradual decrease in carbon content with an increase in the steam/propanol ratio. …”
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658
Use and assessment of “e-plastics” as recycled aggregates in cement mortar
Published 2019“…The obtained results, for all RPs, (especially those of 7.5% and 10%) exhibited an increase in the CS of the specimens by 15.4% and 7.8%, respectively, with the MoE decreased in both cases by 18.1% and 23.8%, respectively. …”
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659
Functionalization of silica-coated magnetic nanoparticles as powerful demulsifier to recover oil from oil-in-water emulsion
Published 2021“…The Fe–Si-MNP exhibited excellent %Soil, reliable stability, and high magnetization values ranging between 46.1 and 80.2 emu/g. adding a 5 nm silica layer on the surface of the Fe–Si-MNP (i.e., Fe–Si-1) protected them from oxidation conditions, extended their service life, and achieved a %Soil of ∼96.3%. …”
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660
Study on adaptive thermal comfort in Japanese offices under various operation modes
Published 2017“…The lower and upper limits of the optimum comfort temperature is approximately 23.5C and 26.6C in mixed-mode. In addition, it is seen that the optimum comfort temperature tends to increase and decrease at very low and high outdoor air temperatures respectively. …”
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