Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes by Manjunath Ramanjaneya (14603468)

“…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
Get full text
Get full text
Get full text

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…There were related increases in FL-linked AGEs, Nε-carboxymethyl-lysine (CML) and 3-deoxylglucosone-derived hydroimidazolone 3DG-H, and minor changes in protein oxidative and nitration adducts. In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
Get full text
Get full text
Get full text

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…There were related increases in FL-linked AGEs, Nε-carboxymethyl-lysine (CML) and 3-deoxylglucosone-derived hydroimidazolone 3DG-H, and minor changes in protein oxidative and nitration adducts. In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma Younes (6424865)

“…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”

The effect of advanced hybrid closed loop system on glycated hemoglobin (HbA1c) in a young male with type 1 diabetes mellitus and growth hormone treatment: A case report by Goran Petrovski (129836)

“…<p dir="ltr">The advanced hybrid closed loop system MiniMed 780G can be an effective tool to improve glycemic control and decrease the health burden in a young male with type 1 diabetes and short stature.…”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
Get full text
Get full text
Get full text

A 28 nm CMOS 10 bit 100 MS/s Asynchronous SAR ADC with Low-Power Switching Procedure and Timing-Protection Scheme by Fang Tang (116243)

“…The power consumption is 1.1 mW with a supply voltage of 0.9 V, leading to a figure of merit (FoM) of 35.6 fJ/conversion-step.…”

Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform by Angelin Mary Philip (21547421)

“…Further, treatment of cells with pitstop2, but not blebbistatin, resulted in a decrease in the S1-RBD depletion. Endocytosis likely plays a role in the initial interaction between S1-RBD and host cells, with the omicron variant showing enhanced interaction and depletion. …”

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…<h3>Introduction</h3><p dir="ltr">Neuropilin-1(NRP1) is a cofactor that enhances SARS-CoV-2 coronavirus cell infectivity when co-expressed with angiotensin-converting enzyme 2(ACE2). …”

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Raed Shalaby (3756112)

“…The IC₅₀ values were found to be in the micromolar to submicromolar range. The <i>K</i>_<em>i</em> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …”

Drying Studies of Purple Non-Sulphur Bacterial Biomass and Application as a Single-Cell Protein Feed for <i>Litopenaeus vannamei</i> by Asifa Anwar (20884229)

“…Purple non-sulphur bacteria (PNSB) are one organism with a strong potential for single-cell protein. …”

The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis by Hoda Gad (6470522)

“…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …”

Effectiveness of 2D magnesium phosphate hydrogel for surgical decontamination of dental implants: A case series by Sara Behmanesh (22391968)

“…The study encompassed eight cases with a history of peri‐implantitis. Clinical measurements were recorded before and after treatment, including bleeding on probing, suppuration, and probing depth. …”

The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)

“…Moreover, tirzepatide exhibited favorable effects on glycemic control, with notable reductions in HbA1c levels ranging from 20.4 mmol/mol with the 5 mg dose to 28.2 mmol/mol with the 15 mg dose, following treatment durations lasting 40–52 weeks. …”

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis by Maria K. Smatti (4675852)

“…Earlier studies identified single nucleotide polymorphisms (SNPs) associated with SARS-CoV-1 in Eastern Asian (EAS) populations. In this report, we aimed at exploring the frequency of a set of genetic polymorphisms that could affect SARS-CoV-2 susceptibility or severity, including those that were previously associated with SARS-CoV-1.…”

Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene by Nagham Nafiz Ahmad Hendi (19938204)

“…I determined a cytoplasmic localization of SDR42E1 protein in the cutaneous HaCat and intestinal HCT116 cells. …”