Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia حسب Fernández-Murray1, J. Pedro

"…The data were consistent with Hem25 not being the sole mitochondrial glycine importer, and we identify a second SLC25 family member Ymc1, as a potential secondary mitochondrial glycine importer. …"
احصل على النص الكامل
احصل على النص الكامل

Experimental and numerical investigation of the flexural behavior of one-way RC slabs strengthened with near-surface mounted and externally bonded systems حسب Aljidda, Omar

"…In contrast, the slabs reinforced with EB experienced a decrease in ductility ranging from 38 % to 50 %. …"
احصل على النص الكامل
احصل على النص الكامل

Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis حسب Elleuch, Jihen

"…However, a protection against excessive degradation of protoxin and toxin forms of Cry1Ac was strongly decreased in the case of δ-endotoxins produced in the presence of P20 as compared to those from P20 lacking control. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

"…Moreover, selective inhibition of Src or PI3K resulted in a significant decrease in the phosphorylation of ERK and AKT, but not p38, demonstrating that PACAP signaling follows Src/Raf/ERK and PI3K/AKT pathways. …"
احصل على النص الكامل
احصل على النص الكامل

Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation. حسب Saleh, Alaaeldin I

"…Thus, EA plant extract causes a dramatic decrease in cell invasion and motility abilities of FaDu and SCC25 cancer cells in comparison with their controls. …"
احصل على النص الكامل
احصل على النص الكامل

Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase حسب Abdulrahman N.

"…The Na+/H+ exchanger isoform 1 (NHE1), a multifunctional protein and the key pH regulator in the heart, has been demonstrated to be increased in this condition. …"
احصل على النص الكامل
احصل على النص الكامل

The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages حسب Al-Awad, Duha

"…We found that soluble uric acid enhanced autophagy flux in infected macrophages. We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Deep Reinforcement Learning Powered IRS-Assisted Downlink NOMA حسب Shehab, Muhammad

"…Simulation results reveal that the IRS-assisted NOMA system based on our utilized DRL scheme achieves a high sum-rate compared to OMA-based one, and as the transmit power increases, the capability of serving more users increases. …"
احصل على النص الكامل
احصل على النص الكامل

Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart حسب Akhtar, Saghir

"…Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

An evidence base for school health policy during the covid-19 pandemic حسب Badran, S.

"…Methods: We gathered age-specific COVID-19 case counts and identified mortality data for 14 countries. …"
احصل على النص الكامل
احصل على النص الكامل

Supramaximal-Exercise Training Improves Heart Rate Variability in Association With Reduced Catecholamine in Obese Adults حسب Jabbour, Georges

"…In this study, 19 OB [22.9 (8.4) years; body mass index (BMI) 33.4 (1.4) kg/m2] and 18 NW [23.2 (4.4) years; BMI 23.3 (1.2) kg/m2] adults completed a 6-week SET intervention. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (CoxFe1?xFe2O4) with theoretical studies حسب Babukutty, B.

"…Faraday rotation of CoxFe1?xFe2O4 ferrofluids is measured depending on the different concentrations of cobalt in applied magnetic field. …"
احصل على النص الكامل
احصل على النص الكامل

MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS حسب Hourani, Shireen Bayan

"…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …"
احصل على النص الكامل

Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling حسب Alotaibi, Mohammed F.

"…Umbelliferone (UMB) is a coumarin with known medicinal and protective properties against cytotoxicity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. حسب Gomes da Silva, Isaura Isabelle Fonseca

"…Rheumatoid arthritis (RA) is a well-known chronic inflammatory disorder. Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …"
احصل على النص الكامل
احصل على النص الكامل

Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants حسب El-Basiony, Nasser M.

"…The Tafel polarization revealed that at 0.1mM of LAPG and MAPG, the corrosion current density (i corr) of CS was reduced to the lowest extent (75.56 and 53.82μAcm-2) compared to 529.3μAcm-2 in the absence of the inhibitors. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. حسب Sara, Sokary

"…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Tailoring the deposition of MoSe2 on TiO2 nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting حسب Ahmad, Yahia H.

"…Compared to pure TiO2 NRs, the heterojunction nanostructured assembly displayed excellent spectral and photoelectrochemical properties, including more surface oxygen vacancies, enhanced visible-light absorption, higher photocurrent response, and decreased charge transfer resistance. In particular, the sample synthesized by sputtering of MoSe2 for 90 s, i.e., MoSe2@TiO2-90 s, depicted the highest current density (1.86 mA cm−2 at 0.5 V vs. …"
احصل على النص الكامل
احصل على النص الكامل

Modeling of mass transport of aqueous solutions of multi-solute organics through reverse osmosis membranes in case of solute–membrane affinity: Part 1. Model development and simula... حسب Mehdizadeh, H.

احصل على النص الكامل
احصل على النص الكامل

A Model For A Narrow-Cut Fractionating Column حسب Farag, Hassan A.

"…A mathematical model was developed to simulate the operation of a narrow-cut fractionating column. …"
احصل على النص الكامل