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Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives
Published 2023“…Introduction: The anticancer and anti-inflammatory activities of a novel series of eleven pyrimido[1,2-b]pyridazin-2-one analogues substituted at position 7 were assessed in the current study. …”
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Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells
Published 2021“…Thiostrepton led downregulation of FoxM1 accompanied by decreased expression of Aurora kinase A, B, matrix metalloproteinases, and oncogene SKP2 as well as MTH1. …”
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Awareness of disabilities in pharmacy program recruitment material: are we doing enough?
Published 2020“…Introduction: Targeted recruitment of students with disabilities is a novel area in pharmacy education and may help to attract qualified students in light of decreasing applicant numbers. …”
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The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells.
Published 2019“…The toxic effects of Pb on the lung was associated with significant increases in NF-κB and AhR levels which was accompanied with increases in downstream targets genes, iNOS and CYP1A1, respectively. …”
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In vitro effects of photobiomodulation therapy on 50B11 sensory neurons: evaluation of cell metabolism, oxidative stress, mitochondrial membrane potential (MMP), and capsaicin-indu...
Published 2021“…Calcium peak stimulated by capsaicin, the ligand of TRPV1 channel, was decreased in neurons pre-irradiated with the combination of the two wavelengths. …”
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Anticancer activity of Neosetophomone B, A Fungal Secondary Metabolite, against Hematological Malignancies
Published 2021“…We tested a panel of leukemic cell lines with different doses of NSP-B. Cell viability decreased in a concentration-dependent manner in K562 and U937 cell lines. …”
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Aluminum nitride (AlN) reinforced electrodeposited Ni-B nanocomposite coatings
Published 2020“…The influence of addition of AlN nanoparticles (0.6 and 1.2 g L−1) on the morphological, mechanical and corrosion protection efficiency of Ni–B nanocomposite coatings was explored using SEM, XPS, XRD, AFM and electrochemical techniques. …”
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Evidence of two mechanisms involved in Bacillus thuringiensis israelensis decreased toxicity against mosquito larvae: Genome dynamic and toxins stability
Published 2015“…This bacterium is characterized by a dynamic genome able to win or lose genetic materials which leads to a decrease in its effectiveness. …”
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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes
Published 2015“…Methods: The objective of this study was to test the effects of DHA on the hypoxia responses (1.0 % for 24 hours) of 3T3-L1 adipocytes with a focus on oxidative stress, inflammation, and mitochondrial function, and antioxidant status. …”
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The Impact of COVID-19 on Physical (In)Activity Behavior in 10 Arab Countries
Published 2022“…Insufficient physical activity is considered a strong risk factor associated with non-communicable diseases. …”
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A LONG-TERM 10G-HYPERGRAVITY EXPOSURE PROMOTES CELL-CELL CONTACTS AND REDUCES ADHESIVENESS TO A SUBSTRATE, MIGRATION, AND INVASIVENESS OF MCF-7HUMAN BREAST CANCER CELLS.
Published 2022“…Cells were exposed to 10 g force for 10 days, as part of a 6-week simulation of conditions of a space flight. …”
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Adaptive thermal comfort in the different buildings of Darjeeling Hills in eastern India – Effect of difference in elevation
Published 2018“…Whereas, the mean comfort temperature decreased with the elevation of the location and this difference was also statistically significant, t = −92.34 (df = 2607, p < 0.001). …”
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