Belinostat decreases both male and female bladder weights in transgenic superficial bladder cancer mice by Michael T Buckley (37161)

“…Normal non-transgenic mouse bladders weigh approximately 10.0 mg at the same age, and Ha-transgenic mice with superficial bladder cancer have a 3 fold and higher bladder weight. , Male belinostat-treated mice (n = 4, 327.5 mg average weight) showed a two-fold decrease (50%, p = 0.03) in bladder weight versus control (n = 4, 652.5 mg average weight). , Female belinostat-treated mice (n = 5, 34.0 mg average weight) showed a 36% decrease (p = 0.04) in bladder weight versus control (n = 6, 53.3 mg average weight).…”

Genomic inactivation of the <i>PIWI</i> gene in <i>L. infantum</i> and <i>L. major</i> strains leads to a decrease in amastigote growth and disease pathology. by Prasad K. Padmanabhan (85254)

Inhibition of Rab5 Activity Decreases Fluid-Phase Uptake by Carsten Schnatwinkel (48)

LRP deficiency in MΦ's results in normal IFN-γ response but decreased IL-4. by Roman Covarrubias (602292)

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-1 by Mrigank Srivastava (94935)

“…. + indicates significant increase (p < 0.05) compared to mock-treated wild-type mice.<p><b>Copyright information:</b></p><p>Taken from "Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis"</p><p>http://respiratory-research.com/content/9/1/54</p><p>Respiratory Research 2008;9(1):54-54.…”

Increase of <i>miR-129-5p</i> expression in Hela cells decreased HPV-18 <i>E6</i> and <i>E7</i> viral gene expressions. by Jiarong Zhang (223696)

Constitutive KIT activation in cells with gain-of function KIT mutations causes increased ROS levels and decreased DJ-1. by Do-Kyun Kim (2176492)

<i>Tnks</i> DKO leads to decreased Wnt/β-catenin signaling activity. by Pan Ye (2902336)

The proportion of Treg decreases and the proportion of Th17 cells increases, but the absolute numbers of both are increased. by Yong-jun Liu (5660170)

“…<p><b>(A and B)</b> At the time of bile ductal obstruction, flow cytometry analysis showed that the percentage of Tregs decreased but Th17 increased in the liver of the RRV group compared to the saline group. …”

Selective BET inhibition decreases intracellular lipid, alters insulin gene expression and improves insulin production in the pancreatic β-cell. by Jude T. Deeney (335344)

Cardamonin inhibited tumor growth and decreased FASN and Raptor. by Peiguang Niu (17044532)

“…Cardamonin reduces the protein expression of Raptor, thereby inhibiting the mTORC1-regulated DNL pathway. This leads to a decrease in free fatty acid levels. …”

Downregulation of LGR4 decreases ARPE-19 cell migration. by Qiang Hou (495704)

Poly (I:C) decreases HIV-1 transcription in cervical tissues by enhancing IRF7 mediated antiviral responses and reducing RelA expression. by Christiane Rollenhage (762318)

Decreased phosphorylation of Lck substrates in Hut-shLAT cells depends on TCR stimulation strength. by Shen Dong (236525)

Blocking the C/EBPβ-Thr217 phosphorylation decreases the Bleomycin-induced activation of LMF. by Martina Buck (82941)

Basal IKK activity is decreased in cells lacking IRE1. by Arvin B. Tam (124164)

Competition localization increases with growth rate or the distances between colonies, and decreases with the resource diffusion constant. by Jeremy M. Chacón (8259792)

Percentage of normal/intermediate/poor metabolizers, or persons with decreased or poor transporter function of SLCO1B1 or reduced expression of VKORC1, showing high proportions of potentially deviating drug responses to warfarin, atorvastatin and metoprolol. by Riccardo Proietti (15332861)

“…<p>Percentage of normal/intermediate/poor metabolizers, or persons with decreased or poor transporter function of SLCO1B1 or reduced expression of VKORC1, showing high proportions of potentially deviating drug responses to warfarin, atorvastatin and metoprolol.…”

Blocking VIP-signaling decreased inflammation and necrosis in the liver and lung of mCMV-infected mice. by Jian-Ming Li (319425)

KPn infection decreases the level of surface exposed phosphatidylserine (PS) and reduces efferocytosis of infected neutrophils. by Christopher N. Jondle (5807657)