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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…Decreased formation and increased clearance of MG-derived AGEs may be associated with healthy aging in the HSA-mUCP1 mouse.…”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. …”
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Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming
Published 2024“…On the other hand, at the same time-on-stream LaNiMgO-Rh lost 0.3 and 0.7 % of its maximum CO2 and CH4 conversions, respectively.In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO2 conversion from 77.6 % to 70.5%, the CH4 conversion decreased from 72.3% to 64.2%. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
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Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published 2021“…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …”
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Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings
Published 2024“…The impact of corrosion is widespread, affecting structures, equipment, and infrastructure across various industries increasing the maintenance cost and thereby decreasing profit and efficiency. Nickel-based coatings are one of the most tempting options owing to their enhanced mechanical and corrosion-resistant properties. …”
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Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar
Published 2020“…Three depositional sectors are delineated: 1) an energetic, linear, fault-controlled Entrance Channel into which the eolian dunes spill directly; 2) a relatively deep (up to 20 m) Outer Lagoon, interpreted to represent a flooded karst-collapse structure; and 3) a sprawling, low-energy, shallow (<2 m) Inner Lagoon occupying low-lying areas between deflated eolian dunes.Physical oceanographic modeling, integrating multi-seasonal current meter and tidal gage measurements, demonstrates tidal current flow velocities are relatively high in both the Entrance Channel and at the constricted entrance to the Inner Lagoon. …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Specifically, we designed Mpro biosensors containing 2×, 4× and 8× repeats of Mpro N-terminal autocleavage sequences and a combination of Mpro cleavage sequences containing a total of 12 cleavage sites sandwiched between mNeonGreen (mNG) and NanoLuc (NLuc). Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. …”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…One bryophyte species (Dicranum elongatum) among the six most commonly found decreased with proximity to the trail. …”
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Human health risks associated with the consumption of groundwater in the Gaza Strip
Published 2023“…For all metals and metalloids analyzed, HQ were below one (HQ1) indicating no risk; however, Sr presented an HQ 95th percentile equal to 0.19. …”
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Detailed organic characterization of process water to evaluate reverse osmosis membrane fouling in industrial wastewater treatment
Published 2024“…Moreover, LC-OCD analysis showed that the ACF inlet has a TOC concentration of approximately 3.06 mg/L; of those 1.29 mg/L (42 %) are hydrophobic, and 1.77 mg/L (58 %) are hydrophilic. …”
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach
Published 2023“…However, biological contamination is one of the most critical problems associated with large scale algal production, especially in open systems such as raceway ponds. …”
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Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
Published 2016“…Clinoleic loaded with paclitaxel decreased the viability of U87-MG cell to 6.4±2.3%, compared to Intralipid loaded with paclitaxel (21.29±3.82%). …”
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Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers
Published 2022“…The modified converter contains mainly-one diode, two capacitors, and Coupled Inductor (CI). …”
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Ultra-low thermal conductivity in scheelite and A-deficient scheelite ceramics
Published 2021“…BaMoO ceramic has shown a decrease in thermal conductivity from 0.8 W m K to 0.65 W m K from 400 K to 650 K. …”
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