Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation. حسب Saleh, Alaaeldin I

"…Our findings indicate that EA plant extract can reduce human oral cancer progression by the inhibition of angiogenesis and cell invasion via Erk1/Erk2 signaling pathways.…"
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart حسب Akhtar, Saghir

"…Methods: Hearts isolated from male Wistar rats underwent regional I/R and/or treatment with different PAMAM dendrimers, Ang-(1-7) or its MAS receptors antagonists. …"
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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center حسب Hammad Y.A.

"…s request until blood is ready for collection, T1); processing time (time from the arrival of technician to blood bank and start of paperwork processing at the blood bank?…"
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Decreasing the use of edible oils in China using WeChat and theories of behavior change: study protocol for a randomized controlled trial. حسب Zhu, Rui

"…Described by Forbes as one of the world's most powerful apps, WeChat provides considerable convenience in disseminating knowledge. …"
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells حسب Zibara, Kazem

"…Results showed that MCF-7 cells express VPAC1 and VPAC2, but not PAC1, receptors. In addition, PACAP increased the phosphorylation levels of STAT1, Src and Raf within seconds, confirming their involvement in early stages of PACAP signaling whereas maximal phosphorylation of AKT, ERK and p38 was reached 10 to 20 min later. …"
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

"…FindingsWe pooled 1479 studies that had measured the blood pressures of 19·1 million adults. Global age-standardised mean systolic blood pressure in 2015 was 127·0 mm Hg (95% credible interval 125·7–128·3) in men and 122·3 mm Hg (121·0–123·6) in women; age-standardised mean diastolic blood pressure was 78·7 mm Hg (77·9–79·5) for men and 76·7 mm Hg (75·9–77·6) for women. …"
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants حسب Bin, Zhou

"…FindingsWe pooled 1479 studies that had measured the blood pressures of 19·1 million adults. Global age-standardised mean systolic blood pressure in 2015 was 127·0 mm Hg (95% credible interval 125·7–128·3) in men and 122·3 mm Hg (121·0–123·6) in women; age-standardised mean diastolic blood pressure was 78·7 mm Hg (77·9–79·5) for men and 76·7 mm Hg (75·9–77·6) for women. …"
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Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (CoxFe1?xFe2O4) with theoretical studies حسب Babukutty, B.

"…Faraday rotation of CoxFe1?xFe2O4 ferrofluids is measured depending on the different concentrations of cobalt in applied magnetic field. …"
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The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages حسب Al-Awad, Duha

"…We found that soluble uric acid enhanced autophagy flux in infected macrophages. We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …"
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Caprylamidopropyl Betaine as a Highly Efficient eco-friendly Corrosion Inhibitor for API X120 Steel in 1 M H2SO4 حسب Foudaa, Abd El Aziz S.

"…CORROSION inhibition of API X120 steel in a 1M sulfuric acid solution at altered temperatures was investigated utilizing a new eco-friendly surfactant (Caprylamidopropyl Betaine (CAPB)) by Gravimetric and electrochemical test (containing potentiodynamic polarization (PP), electrochemical impedance spectroscopy (EIS). …"
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Alhujaily, Muhanad

"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression. …"
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Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling حسب Alotaibi, Mohammed F.

"…In addition, UMB attenuated oxidative stress and oxidative DNA damage, downregulated the expression of pro-inflammatory mediators and Bax, boosted antioxidant defenses and Bcl2, and upregulated Nrf2/HO-1 signaling in Pb-intoxicated rats. Conclusion: UMB prevents Pb-induced testicular injury by suppressing oxidative damage, inflammation and cell death, and boosting antioxidant defenses, Nrf2/HO-1 signaling and pituitary-gonadal axis. …"
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Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar حسب Chemaitelly, Hiam

"…Incidence rate for severe, critical or fatal COVID-19 throughout the pandemic was 1.43 (95% CI 1.35 to 1.50) per 1000 person years. …"
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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation حسب El Hasasna, Hussain

"…Furthermore, we found that while both autophagy inhibitors abolished p38 phosphorylation, only CQ led to significant decrease in pERK1/2. Finally, RCE induced DNA damage and reduced mutant p53, two events that preceded autophagy. …"
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Supramaximal-Exercise Training Improves Heart Rate Variability in Association With Reduced Catecholamine in Obese Adults حسب Jabbour, Georges

"…The improvement in LH and HF were associated with VO2max increases (β = 0.22 p = 0.01 and β = 0.33; p = 0.01). The decreases observed for the LF/HF ratio are mainly associated to NA decreases observed at rest (β = 0.31; p = 0.001) and at VT1 (β = 0.38; p = 0.001). …"
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Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants حسب El-Basiony, Nasser M.

"…The Tafel polarization revealed that at 0.1mM of LAPG and MAPG, the corrosion current density (i corr) of CS was reduced to the lowest extent (75.56 and 53.82μAcm-2) compared to 529.3μAcm-2 in the absence of the inhibitors. …"
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …"
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S1.P170 A terpenoids-enriched fraction of Inula viscosa: its chemical composition and anti-cancerous effects against human lung cancer cells حسب Seglab, Fatiha

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Modeling of mass transport of aqueous solutions of multi-solute organics through reverse osmosis membranes in case of solute–membrane affinity: Part 1. Model development and simula... حسب Mehdizadeh, H.

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The role of type II FB (I):Tl+ defect in laser light generation and color image formation at the low coordination surface sites of AgBr: Ab initio calculations حسب Shalabi, A.S.

"…All relaxed excited states of the defect containing surfaces were deep below the lower edges of the conduction bands of the ground-state defect-free surfaces indicating that type II FB(I):Tl+ is suitable laser defect. The probability of orientational destruction of the two centers, attributed to the assumed saddle point ion configurations along the 〈1 1 0〉 axis, was found to decrease as the coordination number of the surface ions decreases. …"
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