A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country حسب Zaghloul, Nancy

احصل على النص الكامل
احصل على النص الكامل

The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages حسب Al-Awad, Duha

"…We found that soluble uric acid enhanced autophagy flux in infected macrophages. We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Caprylamidopropyl Betaine as a Highly Efficient eco-friendly Corrosion Inhibitor for API X120 Steel in 1 M H2SO4 حسب Foudaa, Abd El Aziz S.

"…CORROSION inhibition of API X120 steel in a 1M sulfuric acid solution at altered temperatures was investigated utilizing a new eco-friendly surfactant (Caprylamidopropyl Betaine (CAPB)) by Gravimetric and electrochemical test (containing potentiodynamic polarization (PP), electrochemical impedance spectroscopy (EIS). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Alhujaily, Muhanad

"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effects of SARS-CoV-2 Alpha, Beta, and Delta variants, age, vaccination, and prior infection on infectiousness of SARS-CoV-2 infections حسب Qassim, Suelen H.

"…Children <10 years of age had 2.18 higher Ct cycles (95% CI: 1.88-2.48) than those 10-19 years of age. Compared to unvaccinated individuals, the Ct value was higher among individuals who had received one or two vaccine doses, but the Ct value decreased gradually with time since the second-dose vaccination. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Umbelliferone inhibits spermatogenic defects and testicular injury in lead-intoxicated rats by suppressing oxidative stress and inflammation, and improving Nrf2/HO-1 signaling حسب Alotaibi, Mohammed F.

"…In addition, UMB attenuated oxidative stress and oxidative DNA damage, downregulated the expression of pro-inflammatory mediators and Bax, boosted antioxidant defenses and Bcl2, and upregulated Nrf2/HO-1 signaling in Pb-intoxicated rats. Conclusion: UMB prevents Pb-induced testicular injury by suppressing oxidative damage, inflammation and cell death, and boosting antioxidant defenses, Nrf2/HO-1 signaling and pituitary-gonadal axis. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

L5 Spinal Nerve Axotomy Induces Distinct Electrophysiological Changes in Axotomized L5- and Adjacent L4-Dorsal Root Ganglion Neurons in Rats . حسب Djouhri, Laiche

"…Consistent with this hypothesis, we found (7 days post-SNA), in SNA rats with established pain hypersensitivity, slower AP kinetics in axotomized L5-neurons and faster AP kinetics in L4-nociceptive neurons including decreased rise time in Aδ-and Aβ-fiber nociceptors, and after-hyperpolarization duration in Aβ-fiber nociceptors. …"
احصل على النص الكامل
احصل على النص الكامل

Supramaximal-Exercise Training Improves Heart Rate Variability in Association With Reduced Catecholamine in Obese Adults حسب Jabbour, Georges

"…The improvement in LH and HF were associated with VO2max increases (β = 0.22 p = 0.01 and β = 0.33; p = 0.01). The decreases observed for the LF/HF ratio are mainly associated to NA decreases observed at rest (β = 0.31; p = 0.001) and at VT1 (β = 0.38; p = 0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0M HCl via multi-carbonyl Gemini cationic surfactants حسب El-Basiony, Nasser M.

"…The Tafel polarization revealed that at 0.1mM of LAPG and MAPG, the corrosion current density (i corr) of CS was reduced to the lowest extent (75.56 and 53.82μAcm-2) compared to 529.3μAcm-2 in the absence of the inhibitors. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

S1.P170 A terpenoids-enriched fraction of Inula viscosa: its chemical composition and anti-cancerous effects against human lung cancer cells حسب Seglab, Fatiha

احصل على النص الكامل

Modeling of mass transport of aqueous solutions of multi-solute organics through reverse osmosis membranes in case of solute–membrane affinity: Part 1. Model development and simula... حسب Mehdizadeh, H.

احصل على النص الكامل
احصل على النص الكامل

Pollution Characteristics of Particulate Matter (PM2.5 and PM10) and Constituent Carbonaceous Aerosols in a South Asian Future Megacity حسب Aslam, Afifa

احصل على النص الكامل
احصل على النص الكامل

An Eco-Friendly Quaternary Ammonium Salt as a Corrosion Inhibitor for Carbon Steel in 5 M HCl Solution: Theoretical and Experimental Investigation حسب Jalab, Rem

"…This study aims to investigate the performance of an environment-friendly Quaternium-22 (Q-22) surfactant which is widely used in cosmetics for C-steel corrosion inhibition in a 5 M HCl medium. Weight loss experiments were performed at different concentrations and immersion times, presenting a maximum efficiency at 2.22 mmol·L−1. …"
احصل على النص الكامل
احصل على النص الكامل

An Improved Fault Tolerant Five-Phase Induction Machine Using A Combined Star/Pentagon Single Layer Stator Winding Connection حسب Abdel-Khalik, Ayman S.

"…A 1kW prototype machine is used for experimental verification.…"
احصل على النص الكامل
احصل على النص الكامل

The impact of COVID-19 pandemic lockdown on smoking habits and lifestyle: A cross-sectional study حسب Khamees, Almu'atasim

احصل على النص الكامل
احصل على النص الكامل

MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. حسب Gomes da Silva, Isaura Isabelle Fonseca

"…Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …"
احصل على النص الكامل
احصل على النص الكامل

Evidence by ac-conductivity for the higher mobility of boron (over aluminium)-associated Brønsted sites in boron-modified HZSM-5 حسب Sayed, Moein B.

"…BZSM-5 conducts with decreasing electric impedance in the order: B1ZSM-5>B2ZSM-5>B4ZSM-5>B3ZSM-5. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon حسب Samaha, Ali A.

"…Methods: A randomized controlled trial was conducted in 100 asymptomatic Lebanese subjects that have tested positive for SARS-CoV2. …"
احصل على النص الكامل
احصل على النص الكامل

Tailoring the deposition of MoSe2 on TiO2 nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting حسب Ahmad, Yahia H.

"…Compared to pure TiO2 NRs, the heterojunction nanostructured assembly displayed excellent spectral and photoelectrochemical properties, including more surface oxygen vacancies, enhanced visible-light absorption, higher photocurrent response, and decreased charge transfer resistance. In particular, the sample synthesized by sputtering of MoSe2 for 90 s, i.e., MoSe2@TiO2-90 s, depicted the highest current density (1.86 mA cm−2 at 0.5 V vs. …"
احصل على النص الكامل
احصل على النص الكامل