The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets حسب Cenciarelli, Carlo

"…Depletion of Hes1 protein induces major changes in cell morphology, cell growth rate and in the invasive ability of shHes1-CSC in response to growth factor EGF. shHes1-CSC show a decrease of the stemness marker Nestin concurrently to a marked increase of neuronal marker MAP2 compared to pLKO.1-CSC. …"
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Nanotargeted Delivery of Immune Therapeutics in Type 1 Diabetes حسب Jung, Sungwook

"…Immune therapeutics holds great promise in the treatment of type 1 diabetes (T1D). Nonetheless, their progress is hampered by limited efficacy, equipoise, or issues of safety. …"
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The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane حسب Rizk, Nasser M

"…Sulforaphane (SFN) has been suggested as a new potential anti-diabetic compound acting by reducing blood glucose levels through mechanisms not fully understood (1). …"
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Drastic difference between hole and electron injection through the gradient shell of Cd: XSeyZn1- xS1- y quantum dots حسب Abdellah, Mohamed

"…Ultrafast fluorescence spectroscopy was used to investigate the hole injection in CdxSeyZn1−xS1−y gradient core–shell quantum dot (CSQD) sensitized p-type NiO photocathodes. …"
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Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells حسب Kuttikrishnan, Shilpa

"…Thiostrepton led downregulation of FoxM1 accompanied by decreased expression of Aurora kinase A, B, matrix metalloproteinases, and oncogene SKP2 as well as MTH1. …"
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Towards An Effective Urban Growth Management Strategy In Qatar (1) حسب Al Thani, F. A. Rahman

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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salloum-Asfar, Salam

"…Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. Previously, we identified five transcription factors, GBX2, NANOGP8, SP8, PEG3, and ZIC1, which may boost iPSC generation. …"
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Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method حسب Gao P.

"…A series of nanostructured Ni-Zn ferrites Ni1-xZn xFe2O4 (x=0, 0.5 and 1) with a grain size from 24 to 65 nm have been prepared with a sol-gel method. …"
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Synthesizing New Anodes From Qatalum's 1st Cut Spl حسب Hani Holozadah, Abdullah

"…For comparison, the anodes were synthesized using the extracted graphite material from the 1st cut SPL, a commercial one and a petroleum coke (PC). …"
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Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets حسب Fardoun, Manal Muin

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Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

"…Results: Under hypoxia conditions, DHA treatment resulted in significant changes in all critical parameters of adipocyte biology including HIF-1α RNA expression (decreased by 50%), decreased lactate and glycerol release (66% and 25% respectively), and reactive oxygen species (ROS) production (decreased by 15%), while glucose uptake was decreased by 25% accompnied by decreased secretion of pro-inflammatory markers (Interleukin 6 IL-6, 31% reduction) , macrophage chemoattractant protein 1 MCP-1 (38% reduction) and leptin (14% reduction), and increased adiponectin secretion (by 45%). …"
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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis... حسب Anwar-Mohamed, Anwar

"…Upon knockdown of AhR and Nrf2 the MMA(V)-, DMA(V)-, and TMA(V)-mediated induction of both CYP1A1 and NQO1 proteins was significantly decreased. …"
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The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy حسب Abdelaziz, Iman Ahmed

"…Our study highlights OPN as a potential therapeutic target to reverse NHE1-induced CH and activity, one which maybe more beneficial than directly inhibiting NHE1.…"
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Effect of plastic deformation on Corrosion of cadmium in 0.1 m sodium Sulphate solution حسب Kandeil, A. Y. [عبد الرزاق يوسف قنديل]

"…The present investigation was carried out to study the influence of prior plastic deformation and surface finish on the corrosion behaviour of pure cadmium in 0.1 M Na2SC>4 solution at 25° C. Cylindrical specimens were deformed by compression to different levels of deformation up to 90% reduction in height (RH). …"
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Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells. حسب Al-Jaber, Hend

"…In vitro, eight sets of 3T3-L1 cells were cultured until they reached 90% confluence. …"
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SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle حسب Koltai, Erika

"…We report here that the levels of miR1 and miR133a decrease in hypertrophy and negatively correlate with muscle mass, SIRT1 and Nampt levels. …"
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model حسب Al-Awar A.

"…Findings show that Sitg (50 mg) resulted in significant decrease in IS and DPP-4 activity, and significant increase in GLP-1, NOS activity, e-NOS expression, TRPV-1 level and TRPC-1 expression, compared to controls. …"
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Synthesis of Metallocene Catalyzed Ethylene 1,7-Octadiene Copolymer: Effect of Copolymerization on Polymer Properties حسب Rahaman M.

"…In this article, metallocene catalyzed polyethylene homopolymer and ethylene 1,7-octadiene copolymers were synthesized and the produced polymers were characterized. …"
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Inhibitory effect of sodium nitrite on corrosion of lead in 0.1 M sodium hydroxide solution حسب Mourad, M.Y.

"…The concentrations of NaNO2 employed are in the range 1-5×10-5. There is a linear relationship between the corrosion potential and the molar concentration of NaNO2. …"
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Genetic Algorithm based SHE-PWM for 1- ø and 3- ø Voltage Source Inverters حسب Kumari, M.

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