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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
m decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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The decrease of C/EBPα protein during apoptosis involves induction of protein degradation and inhibition of transcription.
Published 2009“…<p>(A) After pretreatment with 25 nM of NSC606985 or 0.5 µM of etoposide for 12 hours, NB4 cells were incubated with 10 µg/ml CHX for indicated hours. …”
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Naïve CD8<sup>+</sup> but not CD4<sup>+</sup> T cells were significantly decreased in the periphery of Tsc1 KO mice.
Published 2012“…</b> Total cell number of spleen, pLNs and mLNs of WT and Tsc1 KO mice. <b>C.</b> The percentage of CD8<sup>+</sup>T but not CD4<sup>+</sup>T cells decreased dramatically in all peripheral lymphoid organs of Tsc1 KO mice. …”
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Activated CD4+ CD45RO+ memory T-cells decrease secretion of soluble caspase-1 and P2X7R mRNA expression in monocytes leading to a reduced response upon ATP binding.
Published 2012“…A significant decrease of soluble Caspase-1 in the supernatant of cells co-cultured with activated memory T-cells was observed both in the presence and absence of IFNβ; b) intracellular levels of pro-IL-1β measured with an ELISA specific for the immature precursor of IL-1β showed a significant increase in pro-IL-1β levels in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3), cell lysates from adherent monocytes were obtained after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP c) the ratio of intracellular pro-IL-1β to released soluble Caspase-1 is significantly increased in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3). d) <i>P2X7R</i> mRNA expression in monocytes cultured overnight with activated CD4+CD45RO+ memory T-cells is decreased with and without addition of exogenous IFNβ (n = 3), mRNA was isolated from adherent monocytes after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP (Data are shown as means ± SD of duplicate cultures; *p<0.05; **p<0.01 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations); e) Ca<sup>2+</sup>-influx measurement in monocytes cultured with activated human CD4+CD45RO+ memory T-cells in the presence of IFNβ demonstrates the absence of slow sustained Ca<sup>2+</sup>-influx mediated by ATP binding to the purinergic P2X7-receptor (representative of 3 independent experiments); f) Annexin V staining of monocytes coincubated with T-cells and stimulated with LPS was measured by flow cytometry (representative flow cytometry histogram of n = 5).…”
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NO inhibition (L-NAME) <i>in viv</i>o results in increasing outward current in some PNs (A, B, C) and decreasing inward current in others (D, E, F).
Published 2013“…<b>B</b>. Normalized current I–V plot for control, L-NAME (15 mM), and washout (mean +/− SE; n = 4). …”