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19861
Glycochenodexycholic (GCDCA) causes lumen obstruction and subepithelial fibrosis of neonatal extrahepatic bile ducts (EHBDs), while ursodeoxycholic acid (UDCA) attenuates GCDCA tox...
Published 2022“…<p>(a) Neonatal EHBD were dissected and incubated for 24 hours in biliary epithelial cell media, with or without GCDCA 5mM, and with GCDCA 5mM combined with UDCA acid 5mM. …”
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19862
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19863
Albumin Stimulates the Activity of the Human UDP-Glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the Effects Are Enzyme and Substrate Dependent
Published 2013“…In five newly tested UGTs, 1A7, 1A8, 1A10, 2A1, and 2B15, the addition of BSA enhanced, to a different degree, the in vitro activity by either decreasing reaction’s <em>K</em><sub>m</sub>, increasing its <em>V</em><sub>max</sub>, or both. …”
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19864
Inflammatory cells and expression of IL-17, IL-23, IL-22 and IFN-γ before and during treatment with IMQ 5% cream or MAL-PDT.
Published 2017“…<p>(A) Number of inflammatory cells increased significantly during the inflammatory phase of IMQ treatment (p<0.01) and the early time point of MAL-PDT treatment, while decreased at the late time point (*p<0.05). …”
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19865
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19866
Weighted odds ratios reflecting the impact of a genetically determined 10 mg/dL decrease in LDL-C on pre-specified atherosclerotic traits.
Published 2020“…<p>Odds Ratio and 95% confidence interval is displayed for the effect of a genetically determined 10 mg/dL decrease in LDL-C on primary atherosclerotic traits for White individuals, Black individuals, Hispanic individuals, and inverse variance weighted meta-analysis of White, Black, and Hispanic populations (IVWMA). …”
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19867
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19868
Analysis of HspB1 and HspB5 phosphorylation.
Published 2013“…HeLa cells were either kept untreated (NT) or treated for 2 h with 60 µM menadione. Total cellular protein extracts were analyzed in immunoblots probed with antibodies that are specific for HspB1 or HspB5 and for HspB1 phosphorylation at either serine 15 (Ser15), 78 (Ser78) or 82 (Ser 82) or HspB5 phosphorylation at either serine 19 (Ser19), 45 (Ser45) or 59 (Ser59) (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0070545#s4" target="_blank">Materials and Methods</a>). …”
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19869
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19870
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19871
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19872
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19873
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19874
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19875
Table_5_The Dual Role of AQP4 in Cytotoxic and Vasogenic Edema Following Spinal Cord Contusion and Its Possible Association With Energy Metabolism via COX5A.XLSX
Published 2019“…Meanwhile, AQP4 and COX5A are detected by real-time quantitative PCR (qRT-PCR) and western blot (WB). …”
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19876
DataSheet1_A head-to-head comparison of humoral and cellular immune responses of five COVID-19 vaccines in adults in China.docx
Published 2024“…The neutralizing antibodies GMT of all vaccines showed a significant decrease at V3 compared to V1. The neutralizing antibody GMT against the omicron variant of all vaccines at V1 showed a significant decrease compared to the wild strain. …”
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19877
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19878
EphrinA5 isoforms suppress cell proliferation and migration.
Published 2012“…Ectopic expression of ephrinA5 significantly decreased the cell migratory ability of both cell types. …”
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19879
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19880
Schematic representation of possible mechanism of action of OKN-007 in IC3752 pGBM tumor bearing mice.
Published 2015“…By removing 6-O-sulfates on HS chains and mobilizing protein ligands from HSPG sequestration in the extracellular environment (3), the SULF-2 can increase the solubility of a variety of growth factors (e.g. PDGF) (4) thus increasing the activation of PDGFR-α and downstream signaling pathways in tumor cells (5) [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134276#pone.0134276.ref098" target="_blank">98</a>]. …”