Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach. by Agrahari, Ashish Kumar

“…Therefore, in this study, we used 200 ns molecular dynamic simulation using the GROMACS 5.1.4 package software to investigate the impact of the G2019S substitution on the structure of the kinase domain of LRRK2. …”
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Comparison of demographic and clinical characteristics in distinguishing testicular torsion from torsion of the appendix testis: A single-center retrospective study by Zlatan, Zvizdic

“…Consecutive medical records of all children ≤16 years old with surgically confirmed TT over a period of five years (2011-2016) were collected. …”
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021 by Sirota, Sarah Brooke

“…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …”
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Development of pH-Controlled Aluminum-Based Polymeric Gel for Conformance Control in Sour Gas Reservoirs by Shamlooh M.

“…The results reveal that aluminum acetate, among the screened salts, has a controllable gelation time at pH conditions between 3.5 and 8.5 and is the most stable in the temperature range 25–100 °C. …”
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A Methodology for daylight optimisation of high-rise buildings in the dense urban district using overhang length and glazing type variables with surrogate modelling by Ekici B.

“…Integrating daylight performance in building design supports reducing the energy consumption and satisfying occupants' comfort. This study presents a methodology to optimise the daylight performance of a high-rise building located in a dense urban district. …”
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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation by El Hasasna, Hussain

“…We demonstrated that Rhus coriaria ethanolic extract (RCE) inhibits the proliferation of these cell lines in a time- and concentration-dependent manner. …”
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Fabrication and characterization of flexible ruthenium oxide-loaded polyaniline/poly(vinyl alcohol) nanofibers by Chamakh, M.

“…The tests revealed the decrease of electrical resistivity and activation energy with increasing RuO2 concentration for the as-prepared samples, while the annealed samples showed lower activation energy values of ~0.1 eV with increasing the concentration of RuO2. …”
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Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach by Pavlopoulos, Kosmas

“…The mid Holocene evolution of the borehole area is resulted from the detailed analysis of five sedimentary units detected along the core Matar-1, and includes three distinct stages: (a) from 5253 ± 223 y cal BP to 3138 ± 223 y cal BP, carbonate coarse-grained material consisting of coral fragments, molluscs, calcareous algae and benthic foraminifera are deposited on a shallow marine fringing reefal platform, which becomes progressively a nearshore backreef (around 3675 ± 215 y cal BP), and later (around 3138 ± 223 y cal BP) a reef ramp; (b) since 3040 ± 220 y cal BP the borehole area obtains the characteristics of a high-energy beach that receives increasing inputs of terrigenous material; (c) subsequently, a supratidal backshore setting is established influenced mostly by terrestrial processes and occasionally by marine processes, as it is indicated by the decreasing and sometimes sporadic presence of benthic foraminifera, and recently, a sedimentary veneer consisting of terrigenous, carbonate and evaporite material is formed by terrestrial, mainly wadi and aeolian, processes. © 2018 Elsevier Ltd and INQUA…”
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Perspectives of clinical pharmacists on the provision of pharmaceutical care through telepharmacy services during COVID-19 pandemic in Qatar: A focus group by Alhmoud, Eman

“…Recruitment continued until a saturation point was achieved. Results We conducted five focus groups that included 23 CPs and led to seven themes. …”
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A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact by Gowid, Samer

“…Nonetheless, the consideration of irradiance, electrical, thermal, and weather parameters (scenario IV) yielded higher identification accuracy. The results showed a decrease in the MSE of Vmp by 74.3% (from 1.6 V to 0.411 V), and in the MSE of Imp by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …”
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Reinforcement of polyacrylamide-co-tert-butyl acrylate base gel using nanosilica for conformance control at low and high reservoir temperatures by Shamlooh M.

“…Therefore, this study introduces a new polymeric formulation that serves as a water shut-off agent for reservoirs at low and high temperatures. …”
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The Effect of Visual Impairment and Its Severity on Vision-Related and Health-Related Quality of Life in Jordan: A Comparative Cross-Sectional Study by Jammal, Hisham M.

“…Purpose: To assess the effect of visual impairment (VI), its severity, and ocular diseases on vision-related and health-related quality of life (QoL) in Jordan. Patients and Methods: A comparative, cross-sectional, hospital-based study was conducted among a group of 278 patients with VI aged ≥ 18 years, and age and sex-matched control group of 278 individuals with no VI. …”
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Trends in the global, regional, and national burden of oral conditions from 1990 to 2021: a systematic analysis for the Global Burden of Disease Study 2021 by Eduardo, Bernabe

“…Increasing counts of prevalent cases and DALYs were noted for all oral conditions but untreated caries of deciduous teeth (no percentage change in prevalence or DALYs) and orofacial clefts (–68·3% [–79·3 to –46·5] decrease in DALYs). There were decreases in both age-standardised prevalence and DALY rate for untreated caries of permanent teeth and edentulism, no change in both for untreated caries of deciduous teeth and severe periodontitis, an increase in the prevalence but no change in the DALY rate for lip and oral cavity cancer, and no change in the prevalence but a decrease in the DALY rate for orofacial clefts. …”
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Anticoagulant activity of cellulose nanocrystals from isora plant fibers assembled on cellulose and sio2 substrates via a layer-by-layer approach by Mohan T.

“…The isolated CNCs were monodis-persed and exhibited a length of 200-300 nm and a diameter of 10-20 nm, a negative zetapotential (34-39 mV) over a wide pH range, and high stability in water at various concentrations. …”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Uncertainty from past data inputs and model estimation was propagated throughout analyses by taking 1000 draws for past and present fertility estimates and 500 draws for future forecasts from the estimated distribution for each metric, with 95% uncertainty intervals (UIs) given as the 2·5 and 97·5 percentiles of the draws. To evaluate the forecasting performance of our model and others, we computed skill values—a metric assessing gain in forecasting accuracy—by comparing predicted versus observed ASFRs from the past 15 years (2007–21). …”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Uncertainty from past data inputs and model estimation was propagated throughout analyses by taking 1000 draws for past and present fertility estimates and 500 draws for future forecasts from the estimated distribution for each metric, with 95% uncertainty intervals (UIs) given as the 2·5 and 97·5 percentiles of the draws. To evaluate the forecasting performance of our model and others, we computed skill values—a metric assessing gain in forecasting accuracy—by comparing predicted versus observed ASFRs from the past 15 years (2007–21). …”
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Navigating Cyclone Threats: A Forecast Approach Using Water Streams’ Physical Characteristics as an Indicator to Predict High Risk Potential Areas in the Sultanate of Oman by Al-Awadhi, Talal

“…It was illustrated that the disturbance level differed within the study site, as the highest disturbance occurred in zone C where vegetation coverage decreased by 27% and urban areas by 5%. This zone had dam but still showed the highest amount of water flooding, illustrating that the dam couldn’t prevent the flood due to the differences in the physical characteristics of the streams between the different zones. …”
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Unveiling into Genetic Architecture of Transgenerational Stress Memory via Promoting Drought Tolerance in Barley by Alqudah, Ahmad M.

“…A significant quantitative trait nucleotide (QTN) at position 509,466,648 base pairs, has been identified in the candidate gene HORVU.MOREX.r3.5HG0502630. …”
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Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Jaimie D, Steinmetz

“…Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). …”
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Synthesis and properties of HA/ZnO/CNT nanocomposite by Ding M.

“…The goal of this study was to examine the tribomechanical properties of hydroxyapatite (HA)/ZnO and HA/ZnO/CNT composite ceramics (carbon nanotubes; with different ratios 0.5 wt%, 1.0 wt%, and 1.5 wt%). The composites were synthesized using the hydrothermal method in an autoclave. …”
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