Lowering Melting Points in Asymmetrically Substituted Salen-Copper(II) Complexes Exhibiting Mesomorphic Behavior. Structure of the Mesogen Cu(5-hexyloxySalen) by Reinhard Paschke (553784)

“…In comparison with their symmetrical analogues, unsymmetrically substituted Cu−Salen complexes show mesophases with lowered melting points. For terminally substituted complexes, symmetrical ones (R¹ = R²) have only an S_A phase, while for unsymmetrical alkoxy substitution a monotropic S_E phase occurs and the melting temperature decreases with no loss in mesophase stability. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Depletion of neutrophils is associated with a decreased number of CD4 T cells, B cells, eosinophils, DCs and MDSc during the chronic stages of <i>P</i>. <i>brasiliensis</i> infecti... by Juan David Puerta-Arias (3187089)

Unadjusted and adjusted odds ratios for associations between Stories for Change Diabetes participant characteristics and meaningful change in hemoglobin A1c (HbA1c) from baseline t... by Abby M. Lohr (11263772)

Subjects:

Demographics, IgG anti-<i>T</i>. <i>cruzi</i> score, and location of residence of participants who provided samples used in this study. by Ronald López (18098572)

Histograms showing ranks of selected metrics. by Thomas Hopper (3216453)

IFNAR1 signaling is associated with a decrease in IL-10R⁺ colonic APCs in <i>Salmonella</i>-infected mice. by Kailyn L. Stefan (4633705)

Receiver operating characteristic curve for anti-NIE antibodies for <i>S. stercoralis.</i> by Jannet A. Tobon Ramos (20855642)

“…<p>Using this cut-off, 192 of 283 (68%) in the IDA arm and 180 of 290 (62%) in the DA arm were antibody positive for the <i>S. stercoralis</i> NIE antigen at baseline. Twelve months following MDA, the seroprevalence decreased in the IDA arm to 88 of 212 (41.5%) compared to 100 of 185 (54%) in the DA arm (<i>p</i> = 0.012, chi-square) (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012851#pntd.0012851.t004" target="_blank">Table 4A</a>). …”

Functional reversibility of <i>POLG1</i> variants and mutations. by Bhupendra Singh (343330)

Distribution and characteristics of CD5⁺ and CD5^- B cells in normal mice. by Yoshiyuki Mishima (842248)

The principal coordinates analysis (PCoA) of different pig fecal samples including A1, A2, A3, A4, B5, B6, B7, and B8. by Shuai Huang (60512)

Apparent Diffusion Coefficient (ADC) and Blood Oxygenation Level—Dependent (BOLD) changes and time courses for each dosage of both anesthetic conditions. by Yoshifumi Abe (2577568)

Effect of freeze-thaw cycling on grain size of biochar - Fig 5 by Zuolin Liu (633898)

Depletion of most candidate CIA pathway proteins leads to a decrease in protein translation in <i>Toxoplasma gondii</i> parasites. by Evie R. Hodgson (21866946)

Calculation of braiding angle of internal cell A. by Weiliang Zhang (11231646)

Inhibition of the EphA4-c-Abl pathway decreases the loss of dendritic spines and apoptosis induced by AβOs. by Lina M. Vargas (540995)

Dataset (Figs 2–5). by Xianyong Wang (22601067)

“…Soil organic carbon and organic matter levels tended to increase on day 5 post-fertilization but generally decreased by day 10, with more pronounced declines observed in low-rate treatments (e.g., 1F). …”

Changes in the concentration of FLU ophthalmic suspensions contained in one drop following agitation by different methods. by Tokio Obata (10783047)

<i>P. brasiliensis</i>-infected mice treated with CFA present remarkable decrease of fungal burden and increase of cytokines production. by Leandro Licursi de Oliveira (374413)