The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets حسب Cenciarelli, Carlo

"…In the last decade Stat3 has gained attention as therapeutic target in cancer but there is not yet any approved Stat3-based glioma therapy. Herein, we report that exposure to a Stat3/5 inhibitor, induced apoptosis either in shHes1-CSC or control cells. …"
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Electrical characteristics and density of states of thin-film transistors based on sol-gel derived ZnO channel layers with different annealing temperatures حسب Wang S.

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Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2. حسب Thirumal Kumar, D

"…The D-2-HGA includes two subtypes: type I and type II caused by the mutations in D2HGDH and IDH2 proteins, respectively. In this study, we studied six mutations, four in the D2HGDH (I147S, D375Y, N439D, and V444A) and two in the IDH2 proteins (R140G, R140Q). …"
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Effect of hyperglycemia on EPCs function and regenerative ability حسب Hendawi, Hadeel Khalil

"…This research aims to test the EPC subtype blood outgrowth endothelial cells (BOECs) and their ability to survive and function under chronic hyperglycemic conditions. For that, we studied BOECs viability, response to shear stress, angiogenesis ability, and barrier function under normoglycemic (5.5mM) and hyperglycemic (25mM) conditions. …"
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Dietary L-carnitine and vitamin-E; a strategy to combat ochratoxin-A induced immunosuppression حسب Bhatti S.A.

"…This study aimed to evaluate the effect of dietary ochratoxin A (OA), in the presence and absence of L-carnitine (LC) and vitamin E (VE), on the humoral immune responses of White Leghorn cockerels (WLC). One-day old white male Leghorn chicks were divided into 12 groups, having 20 birds each and were offered ration contaminated with OA (1.0 or 2.0 mg/kg feed) alone and concurrently with LC (1.0 g/kg) and/or VE (0.2 g/kg), for 42 days. …"
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Superior photocatalytic activity of Cu doped NiWO4 for efficient degradation of benzene in air even under visible radiation حسب Tri N.L.M.

"…This was because Cu effectively acted as novel dopant, which not only affected valence band (VB) top and conduction band (CB) bottom of NiWO4 but also formed a medium energy level between CB and VB of the NiWO4 to decrease its energy band gap and electron-hole recombination rate. …"
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Trends in prevalence of depression and anxiety symptoms and effects of sociodemographic variables before and after the first wave of COVID-19 in Qatar حسب Khaled, Salma M.

"…The data for 2020/21 showed a 35.1% and 29.2% decrease in depression and anxiety symptoms scores compared to pre-pandemic years (2017/2018) after adjusting for sociodemographic factors. …"
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Roadmap toward energy-positive upfront nitrogen removal process in baseload LNG plant حسب Mkacher, Hajer

"…The results show that UNrem of 87.5% from the NG feed can reduce the total power requirements by 0.24%, increase the production flow rate by 4.4%, and decrease the exergy losses by 0.23% compared with the base case. …"
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Modeling of dual-metal Schottky contacts based silicon micro and nano wire solar cells حسب Rabbani, M. Golam

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Individual and Synergic Effects of Phosphorus and Gibberellic Acid on Organic Acids Exudation Pattern, Ultra-Structure of Chloroplast and Stress Response Gene Expression in Cu-Stre... حسب Alatawi, Aishah

"…Results revealed that C. capsularis tolerated up to 200 mg kg−1 Cu concentration without a significant (P < 0.05) decrease in biomass, plant height and root length but further increase in Cu concentration from 400 mg kg−1 exhibited a significant reduction in plant height, root length, stem fresh weight, stem dry weight, plant fresh weight and plant dry weight. …"
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Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats حسب Kiss, K.

"…In study 4, AF43136 at 10 mg/kg decreased infarct size, similarly to the positive control CsA compared to the appropriate vehicle (39.4 ± 5.9% vs. 58.1 ± 5.4% and 45.9 ± 2.4% vs. 63.8 ± 4.1%, p < 0.05, respectively). …"
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Enhanced oil recovery using hyperbranched polyglycerol polymer-coated silica nanoparticles حسب Elmobarak W.F.

"…The PSiMNPs can be reused up to 15 times with a steady %?dem of 89.1% for Coil = 100 mg/L and 88.6% for Coil = 4000 mg/L. …"
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Antibiotic Prescription Patterns for Upper Respiratory Tract Infections in Outpatient Qatari Population in the Private Sector حسب Butt, Adeel Ajwad

"…During the study period, health insurance was limited to Qatari nationals. We excluded topical antibiotics. We also retrieved data on prescriber’s specialty as listed with the licensing authority. …"
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Effects of combined calcium hypochlorite and chlorine dioxide on drinking water quality in Qatar and disinfection by-products formation حسب Mohamed, Elsamoul H.

"…Seven water samples were collected from the Ras Laffan-Q Power desalination plant outlet in amber bottles having a chlorine dioxide concentration of 0.3 mg/L in 1 liter. The bottles were spiked with Ca(ClO)2 in sequence to give concentration of 0.2, 0.4, 0.6, 0.8, 1.0, and 1.2 mg/L as free chlorine. …"
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Corporate governance and cost of debt financing: Empirical evidence from Canada حسب Ghouma, Hatem

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Effect of mobile text messages on antiretroviral medication adherence and patient retention in early HIV care: An open-label, randomized, single center study in south Florida حسب Sherman, Elizabeth M.

"…Background People with HIV (PHIV) with limited access to health services often experience suboptimal antiretroviral therapy (ART) adherence. We investigated whether a daily text messaging intervention improves ART adherence and retention in early HIV care in PHIV in a south Florida hospital-based clinic. …"
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Changes In Biomass Gain, Protein Content And Hormonal Levels In Wheat Kernels In Response To Soil Drench With Sodium Salicylate حسب Abo Hamed, S. A.

"…Drenching of soil with sodim salycylate (800,4000 and 8000mg/l) increased grain f. wt. and d. wt. Protein content was increased in grains at days 23 and 60 with 800 mg/1 salicylate. …"
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Integrated planning of spare parts and service engineers with partial backlogging حسب Rahimi-Ghahroodi, S.

"…In a numerical study, we show that for problems with more than five types of spare parts it is preferable to use approximate evaluations as they become significantly faster than exact evaluation. …"
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Evacuated tube heat pipe solar collector for Encontech engine-driven reverse osmosis solar desalination حسب Takalkar, Gorakshnath

"…Both energetic and exergetic efficiencies exhibit upper values at A co/A abs ratio up to 1. Further increment in this ratio up to 3 resulted in a decrease in the efficiency of the ETHPSC.…"
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Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis حسب Manresa M.C.

"…Background When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular hypoxia. …"
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