AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro by Allouch, Soumaya

“…Moreover, higher concentrations of albumin, particularly 30 mg/ml, caused severe induction of ER stress and EMT, marked by 20-fold increase in CHOP and 6-fold increase in a-SMA respectively. Similarly, the phosphorylation of AKT and P70S6K (a downstream target of mTOR) was increased by more than 1.5-fold in cells subjected to albumin treatment. …”
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Inter-annual variability and distribution of aerosols during winters and aerosol optical thickness over Northeastern Pakistan by Shahid, M. Z.

“…ir pollution during winters over north-eastern (NE) Pakistan (71–74.5 E, 28–34 N) is a major challenge that affects human health, climate and daily life. …”
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Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM) by Mohammad, Hadi Ahmad

“…The results indicate that the statistical downscaling model (SDSM) is performing satisfactorily in predicting maximum and minimum temperatures, along with precipitation, for the time horizon of the simulation. Mean precipitation of 1.98 mm (RCP2.6), 2.03 mm (RCP4.5), and 2.07 mm (RCP8.5) was revealed in the study area. …”
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Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro by Rizk, Nasser Moustafa

“…In conclusion, this study demonstrated that Hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis, eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours, insulin could counteract the hyperglycemic effect on AKT/pI3 kinase which mediates NO production and VEGF-A, decreased adhesion molecules p-selectin involved in barrier disorder of retinal endothelial cells. …”
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Could Vagus nerve stimulation influence bone remodeling? by Tamimi, Ahmad

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Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2. by Thirumal Kumar, D

“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells by Mannino, Federica

“…Dexamethasone-resistant (MM.1R) and sensitive (MM.1S) human multiple myeloma cell lines were used in this study. …”
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Forecast of the outbreak of COVID-19 using artificial neural network: Case study Qatar, Spain, and Italy by Shawaqfah M.

“…The model sensitivity was analyzed using the root mean square error (RMSE), the mean absolute percentage error and the regression coefficient index R2, which yielded highly accurate values of the predicted correlation for the infected and dead cases of 0.99 for the dates considered. …”
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The Structure of the Free Volume in Poly(styrene-co-acrylonitrile) from Positron Lifetime and Pressure Volume Temperature (PVT) Experiments by Dlubek, Gunter

“…The mean hole volume, vh, varies in PS between 105 Å3 (27 °C) and 220 Å3 (190 °C), and shows a systematic decrease with increasing AN content, at Tg from 121 Å3 for PS to 102 (±2) Å3 for SAN50. …”
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Higher egg consumption associated with increased risk of diabetes in Chinese adults - China Health and Nutrition Survey. by Wang, Yue

“…Egg consumption at each survey was assessed by a 3-d 24-h recall and weighed food record methods. …”
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Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling. by Akhtar, Sabah

“…In this study, we aimed to investigate the potential anti-proliferative and pro-apoptotic activities of SNG in a panel of MM cell lines (U266, IM9, MM1S, and RPMI-8226). …”
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Serum NMR-Based Metabolomics Profiling Identifies Lipoprotein Subfraction Variables and Amino Acid Reshuffling in Myeloma Development and Progression by Pedersen, Shona

“…However, metabolic profiling of MM patients, compared to controls, exhibited decreased levels of total Apolipoprotein-A1, HDL-4 Apolipoprotein-A1, HDL-4 Apolipoprotein-A2, HDL Free Cholesterol, HDL-3 Cholesterol and HDL-4 Cholesterol. …”
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Gas Driven Fracture during Gas Production using HeleShaw Cell by Al-Raoush, Riyadh

“…The cell consists of two transparent acrylic sheets that are separated by a small gap. The gap between the two sheets is maintained using filter sheets that have a thickness of 1/16 in. (1.6 mm) at the boundaries. …”
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Comparison Of In Vitro Models Of Diabetic Nephropathy Using Renal Tubular Cells by El Gamal, Heba

“…Results: MDCK cells showed a subtle decrease in viability when exposed to high glucose concentrations (30 mM and 1% FBS) for 48 h. …”
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Solely abluminal drug release from coronary stents could possibly improve reendothelialization by Zhang, Haijun

“…LLL of BPSES-A, BPSES-C, BMS, and BPS were 0.56 ± 0.51, 0.60 ± 0.58, 0.89 ± 0.43, and 1.68 ± 0.30 mm, respectively, after 4 weeks. LLL of BPSES-A and BPSES-C were 0.63 ± 0.53 and 0.69 ± 0.24 mm, respectively, after 12 weeks. …”
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Flexural Capacity of Sustainable RC Beams Manufactured with Treated Wastewater, RCA, and Fly Ash by Abushanab, Abdelrahman

“…Furthermore, FA showed a 5% to 7% improvement in the ultimate loading capacity of the beams.…”
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Sea water salinity detection using circular fringes formation based on diffraction of laser light by Ali H.

“…As the NaCl solution concentration increases from 0% to 9% (0 g/l - 90 g/I), the radius of the outer most circular fringe decreases from 16.95 mm to 16.45 mm and the refractive index increases from 1.333 to 1.373. …”
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Linear hydrogen gas sensors based on bimetallic nanoclusters by Ayesh, Ahmad I.

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Renoprotective Effects of Aldose Reductase Inhibitor Epalrestat against High Glucose-Induced Cellular Injury by El Gamal, Heba

“…Rat renal tubular (NRK-52E) cells were exposed to high glucose (30 mM) or normal glucose (5 mM) media for 24 to 48 hours with or without the AR inhibitor epalrestat (1 muM) and assessed for changes in Akt and ERK1/2 signaling, AR expression (using western blotting), and alterations in mitochondrial membrane potential (using JC-1 staining), cell viability (using MTT assay), and cell cycle. …”
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Platelet Concentrate Treatments for Temporomandibular Disorders: A Systematic Review and Meta-analysis by Al-Hamed F.S.

“…Regarding MMO measurements, PC was comparable to HA, but it was significantly better than saline after 3 and 6 mo [2.9 mm (CI,1.47 to 4.3; P < 0.0001), and 1.69 mm (CI, 0.13 to 3.25; P = 0.03) respectively]. …”
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