A Y45F mutation in hepatitis C virus NS4A causes a decrease in infectious viral titer. by Allison E. Roder (6312761)

TSA treatment significantly decreases total cholesterol content in neuroblastoma cells. by Maria João Nunes (160499)

<i>In vivo</i> treatment with entinostat decreases Foxp3 expression in Tregs and inhibits Tregs function. by Li Shen (110858)

“…Cells were harvested from spleens and lymph nodes. A, <i>In vivo</i> entinostat treatment decreased the expression level of Foxp3 in CD4⁺Foxp3⁺ (Treg) cells. …”

Waning of BCG-induced protection against <i>Mtb</i> coincides with decreased T-cell functional capacity. by Subhadra Nandakumar (212501)

Testis dysgenesis and decreased reproductive parameters after prenatal exposure to DEHP. by Ludwig Stenz (779897)

Mfsd2a KO mice have decreased liver TG with normal liver metabolism. by Justin H. Berger (297156)

DPPIV inhibitor MK626 decreases T1D incidence and reduces the insulitis score in NOD mice. by Núria Alonso (824191)

HO-1 overexpression decreases Nox4 activity in C-20/A4 chondrocytes. by Francis Rousset (424375)

Reduced I_A decreases the stimulus threshold for short-term synaptic plasticity. by Ángela Fontán-Lozano (193161)

Homozygous deletion of <i>ERG251</i> leads to increased sensitivity to cell membrane and osmotic stress but decreased sensitivity to oxidative stress. by Xin Zhou (54275)

Increased body fat, glucose and PAI-1 and decreased adiponectin levels in 6 wk old WT offspring exposed to HF IU/L. by Patricia M. Vuguin (587226)

Oral UOX decreased SUA (A), BUN (B) and Cr (C) (mean ± SD, n = 10). by Yu Yun (4710340)

NEMO knockout murine dermal fibroblasts show a decreased nuclear translocation of p65. by Patrick Meyer (3395285)

Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at inhibitory synapses: Rescue by WT but not mutant Syt1 or Syt7. by Taulant Bacaj (803415)

“…Recordings were performed in the presence of 1 μM tetrodotoxin, 20 μM CNQX, and 50 μM AP5 to isolate inhibitory currents. <b>B.</b> Simultaneous ablation of Syt1 and Syt7 decreases the RRP size of inhibitory synapses in a manner that is rescued by WT Syt7 (Syt1^WT) but not Syt7 with mutations in the top C2 domain sequences containing the Syt7 Ca²⁺ binding sites (Syt7^C2A*^B*). …”

Decreased reductase activity and increased round body formation in the <i>gpsA</i> mutant. by Dan Drecktrah (36180)

<i>In vivo</i> RCAS-hLPL infection decreases high triglyceride levels in hypertriglyceridemic mice. by Katherine E. Gadek (3276996)

DJ-1 gene deletion decreases mitochondrial respiratory chain function in dopaminergic neuronal cells. by Jun Young Heo (179572)

DOX decreases body mass gain over time in a sub-chronic toxicity model. by Gonçalo C. Pereira (156673)

Overexpression of SV2A-EGFP in wild-type neurons results in reduced EPSC amplitude and decreased synaptic depression. by Amy Nowack (336337)

Mitochondrial dysfunction is driven by decreased mitochondrial dynamics. by Piero Dalle Pezze (622889)

“…Example images from these areas over 140 s are shown below with the detected fusion and fission events highlighted with white and yellow arrows respectively. A timelapse movie containing the full dataset from a control and senescent cell are available in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003728#pcbi.1003728.s027" target="_blank">Movie S1</a>. …”