Showing 281 - 300 results of 108,890 for search '(( 1 point decrease ) OR ( 5 ((wt decrease) OR (((we decrease) OR (a decrease)))) ))', query time: 1.65s Refine Results
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    GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

    Published 2017
    “…The receptors were activated by EC<sub>50</sub> concentrations of glutamate with saturating concentration (100 μM) of glycine at holding potential of -40 mV. The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”
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