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6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…F-53B also induced Parkinson’s disease (PD)-like disorders including dyskinesia (incidence: 22.8–27.9%), dopaminergic neuronal damage (neuritic blebbings and broken neurites) and decreased dopamine levels (15.2–28.1%), increased abundance (1.3–1.4 fold) and aggregation of α-synuclein. …”
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6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…F-53B also induced Parkinson’s disease (PD)-like disorders including dyskinesia (incidence: 22.8–27.9%), dopaminergic neuronal damage (neuritic blebbings and broken neurites) and decreased dopamine levels (15.2–28.1%), increased abundance (1.3–1.4 fold) and aggregation of α-synuclein. …”
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6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…F-53B also induced Parkinson’s disease (PD)-like disorders including dyskinesia (incidence: 22.8–27.9%), dopaminergic neuronal damage (neuritic blebbings and broken neurites) and decreased dopamine levels (15.2–28.1%), increased abundance (1.3–1.4 fold) and aggregation of α-synuclein. …”
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6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations
Published 2025“…F-53B also induced Parkinson’s disease (PD)-like disorders including dyskinesia (incidence: 22.8–27.9%), dopaminergic neuronal damage (neuritic blebbings and broken neurites) and decreased dopamine levels (15.2–28.1%), increased abundance (1.3–1.4 fold) and aggregation of α-synuclein. …”
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We cannot be “forever young,” but our children are: A multilevel intervention to sustain nursery school teachers’ resources and well-being during their long work life cycle
Published 2018“…</p><p>Method</p><p>This study involved twenty-seven preschools (324 teachers with an average age of 48.7 years): the control group included seventeen schools (190 teachers with an average age of 48.5 years), five schools were assigned to experimental group one (69 teachers with an average age of 48.8), and five schools were assigned to experimental group two (65 teachers with an average age of 49.1). …”
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Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx
Published 2022“…We found that IL5Tg mice exhibit reduced pulmonary metastatic colonization and decreased metastatic tumor burden compared to wild-type (WT) mice or eosinophil-deficient mice. …”
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Chemokines, with the exception of CXCL1 and MCP-1, decrease acutely following 5 Gy IR.
Published 2024Subjects: -
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sC5b-9 patients decrease in patients treated with mycophenolate mofetil.
Published 2015“…When analyzed separately based upon treatment, the decrease in sC5b-9 levels was due to a decrease in patients treated with mycophenolate mofetil (P < 0.001 by linear regression; n = 12 for all time-points). …”
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MK-STYX decreases RhoA activation.
Published 2014“…<p>(<b>A</b>) PC12 cells were transfected with pMT2 or pMT2-FLAG-MK-STYX-FLAG. 24 hr post-transfection cells were stimulated with 100 ng/ml NGF, and lysed at the indicated time points. …”
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Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects
Published 2012“…Consistent with its role limiting fatty acid biosynthesis, both <em>BrCa1</em> mRNA (3.5-fold, p<0.0001) and protein (1.2-fold, p = 0.001) were increased in pre-adipocytes, and decreased during <em>in vitro</em> adipogenesis, while P-ACC decreased during differentiation of human adipocytes (p = 0.005) allowing lipid biosynthesis. …”
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