Lipolytic treatment decreased cellular neutral lipids and increased extracellular fatty acids and glycerol. by Caroline Louis (332423)

“…Cellular neutral lipids (corresponding to µmol of fatty acids in cellular neutral lipids) were expressed per mg of total cell protein (A). A significant decrease of cellular lipid contents was noted throughout the lipolytic process for the conditions with PCB-28 (<i>p</i> = 0.005) and the cocktail of PCBs (<i>p</i> = 0.029). …”

Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis by Zeynep Gök Sargın (4678663)

“…GEBOES grading system was also used. We demonstrated a profound loss (69.4%) of NEP expression in UC, whereas all healthy controls had NEP expression. …”

Nepmucin/CD300LG expression is decreased in tumors and tumor-draining lymph nodes. by Eiji Umemoto (1637)

Jurkat and HeLa survival decreases with increasing electric field amplitude and pulse number. by Bennett L. Ibey (357053)

“…For all exposures, Jurkat cells are more sensitive than HeLa cells. Data points represent the average survival. (mean +/−s.e., n = 3–5).…”

Decreased expression of MHCII in antigen presenting cells from the lungs of IL-19-/- mice. by Carol Hoffman (196241)

Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient Hearts by Alexia Vite (462320)

“…</p> <p>Methods and Results</p><p>We examined plakophilin-2, desmoglein-2, desmocollin-2, plakoglobin and β-catenin protein expression levels from seven independent ARVD/C heart samples compared to two ischemic, five dilated cardiomyopathy and one healthy heart sample as controls. …”

Correlations between SARS-CoV-2 specific T cells and FEV₁ and symptoms in PASC. by Katherine M. Littlefield (12647420)

Injection of pNaKtide diminishes PNx-induced decrease in miR-29b-3p expression. by Christopher A. Drummond (3845110)

CsA reduces Flk1 protein expression and significantly decreases the percentages of Flk1+ cells. by Seung-Cheol Choi (686982)

Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis by Eric N. Ouattara (6890174)

“…</p><p>Methods</p><p>We used a mathematical model to compare three potential ART initiation criteria: 1) CD4 <350/μL (<i>ART<350/μL</i>); 2) CD4 <500/<i>μ</i>L (<i>ART<500/μL</i>); and 3) ART at presentation (<i>Immediate ART</i>). …”

PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

Foxm1 deletion after tumor initiation decreases lung tumor expansion/progression. by I-Ching Wang (348231)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

K-fold cross validation accuracy of different models. by Shayla Naznin (13014015)

Subjects:

I890T markedly decreases peak <i>I</i>_Na. by Anna Tarradas (105463)

Regression Results for Average Antibiotic Resistance. by Peter Collignon (704972)

CD107a-, IFNγ- and MIP 1β-producing Vγ9Vδ2 T-cell subsets decrease in HIV+ patients. by Rita Casetti (608635)

Table_1_Unconventional Sea Surface Temperature Regime Around Japan in the 2000s–2010s: Potential Influences on Major Fisheries Resources.docx by Hiroshi Kuroda (769431)

“…In this paper, we review atmosphere and ocean conditions around Japan in the 2000s–2010s in terms of global climate, present an overview of potential impacts of decadal SST trends on five major commercial fisheries resources (walleye pollock, chum salmon, Japanese sardine, Japanese anchovy, and Japanese flying squid), and raise awareness that an unconventional regime can appear transiently during a state of global warming.…”

Decrease of SMAD3 protein, but not SMAD2 in DBA iPSCs. by Jingping Ge (636557)

“…The nuclear p-SMAD2 decreased in <i>RPL5</i> mutant and corrected lines. …”