<i>Escherichia coli</i> Cyclopropane Fatty Acid Synthase:  Is a Bound Bicarbonate Ion the Active-Site Base?^† by Fabienne Courtois (2667262)

“…The crystal structure of three cyclopropane synthases from <i>Mycobacterium tuberculosis</i> showed a bicarbonate ion bound in the active site that was proposed to act as a general base in the reaction mechanism [Huang, C., Smith, V., Glickman, M. …”

<i>Escherichia coli</i> Cyclopropane Fatty Acid Synthase:  Is a Bound Bicarbonate Ion the Active-Site Base?^† by Fabienne Courtois (2667262)

“…The crystal structure of three cyclopropane synthases from <i>Mycobacterium tuberculosis</i> showed a bicarbonate ion bound in the active site that was proposed to act as a general base in the reaction mechanism [Huang, C., Smith, V., Glickman, M. …”

Blocking CD88 decreased ANCA antigen translocation, ANCA-induced respiratory burst and degranulation in C5a-primed neutrophils. by Jian Hao (160736)

“…C and D: blocking CD88 decreased C5a-primed neutrophils for ANCA-induced respiratory burst. …”

Microbiocidal activity and limited bacteria-cell contact does not provide for decreased phagocytic clearance of non-swimming bacteria. by Rustin R. Lovewell (205423)

Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity by Kaytee L. Pokrzywinski (3605435)

“…In this study, we demonstrated that all investigated MTAs impair mitochondrial health and decrease mtDNA integrity in MDA-MB-231 and H23 cells. …”

Data_Sheet_1_The role of booster vaccination in decreasing COVID-19 age-adjusted case fatality rate: Evidence from 32 countries.docx by Cui Zhou (1388874)

MeHg Exposure Makes O-2A/OPCs More Oxidized, Suppresses BrdU Incorporation, and Decreases Cell Division in Clonal Assays by Zaibo Li (273729)

“…In cultures exposed to MeHg, there was a decrease in the representation of large clones and a proportionate increase in the number of small clones and clones containing oligodendrocytes. …”

Phlorizin reduced tissue ATP content in the heart, associated with decreased glucose uptake and glycolytic flux during IRI. by Yusuke Kashiwagi (762406)

Exploring reopening strategies for a wide range in disease transmission <i>v</i>_<i>r</i> with testing capacity. by Mackenzie Dalton (14093874)

Homozygous deletion of <i>ERG251</i> leads to downregulation of ergosterol biosynthesis genes and upregulation of alternate sterol biosynthesis genes. by Xin Zhou (54275)

Descriptive statistics of all results at baseline after a full night of sleep (0 h), after 12 (-12 h), 24 (-24 h) and 36 (-36 h) hours of total sleep deprivation followed by 8 (+8... by Jan Maleček (17396660)

Subjects:

Cross-sectional monitoring point arrangement. by Xingli Jia (13994009)

Subjects:

NMR and EPR Spectroscopic and Structural Studies of Low-Spin, (d_xz,d_y_z)⁴(d_x_y)¹ Ground State Fe(III) Bis... by Liliya A. Yatsunyk (1933270)

“…All structurally-characterized complexes of this electron configuration reported previously are ruffled. Therefore, we conclude that a <i>ruffled geometry stabilizes the </i><i>(d</i><i>_xz,</i><i>d</i><i>_yz</i><i>)</i><i>⁴</i><i>(d</i><i>_xy</i><i>)</i><i>¹</i><i> ground state, but is not necessary for its existence</i>.…”

NMR and EPR Spectroscopic and Structural Studies of Low-Spin, (d_xz,d_y_z)⁴(d_x_y)¹ Ground State Fe(III) Bis... by Liliya A. Yatsunyk (1933270)

“…All structurally-characterized complexes of this electron configuration reported previously are ruffled. Therefore, we conclude that a <i>ruffled geometry stabilizes the </i><i>(d</i><i>_xz,</i><i>d</i><i>_yz</i><i>)</i><i>⁴</i><i>(d</i><i>_xy</i><i>)</i><i>¹</i><i> ground state, but is not necessary for its existence</i>.…”

Chun Fai Martin Cheng: How can we decrease metabolism in the New Zealand green-lipped mussels, Perna canaliculus, for better transport? by Cheng Martin (11717816)

Population dynamics modeling of split^50cM <i>ClvR</i> V1 introduced at a 50% release, with fitness cost per allele varying from 0–15%. by Georg Oberhofer (3401438)

Table_2_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Image_2_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.tif by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_4_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Table_3_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”