Zileuton, 5-Lipoxygenase Inhibitor, Acts as a Chemopreventive Agent in Intestinal Polyposis, by Modulating Polyp and Systemic Inflammation by Elias Gounaris (52393)

“…Here we report that Zileuton, a specific 5-LO inhibitor, can prevent polyp formation by efficiently reducing the tumor-associated and systemic inflammation in APC^Δ468 mice.…”

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulat... by Rodrigo A Fuentealba (77901)

The decrease of C/EBPα protein during apoptosis involves induction of protein degradation and inhibition of transcription. by Meng Zhao (54299)

“…Then, C/EBPα protein was detected with β-actin as a loading control. Folds of decrease of C/EBPα protein/β-actin ratios against untreated cells are shown as means±SD of three independent experiments. …”

This is the raw data of IHC-1 in Rat. by Yangyang Yin (14323701)

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Changes in plasma luteinizing hormone levels and P4/E2 sex hormone ratios as a result of cetrorelix treatment (Fig 7). by Kalman F. Szucs (19353218)

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Chimera and wild-type virus replication at early time points. by Anja vom Hemdt (19787189)

Supplementary Material for: TNFAIP2 Inhibits Early TNFa-Induced NF-κB Signaling and Decreases Survival in Septic Shock Patients by Thair S.A. (4152325)

“…Using tag single-nucleotide polymorphisms in the genes common to all data sets, we identified a genetic variant of the <i>TNFAIP2</i> gene, rs8126, associated with decreased 28-day survival and increased organ dysfunction in an adult cohort in the Vasopressin and Septic Shock Trial. …”

Shortening of mTL anticipates accumulation of DDR markers, decrease in cell proliferation and increase in apoptotis with age. by Madalena C. Carneiro (102302)

“…Proliferative tissues, A) gut B) kidney marrow and C) testis, show a sustained decrease in cell proliferation by 12 months of age in <i>tert</i>^<i>-/-</i> (panels g, i) and by 36 months in WT tissues (panels f, h and j). …”

A Point Mutation in a lincRNA Upstream of <i>GDNF</i> Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies by Jocelyn Plassais (564630)

“…Clinical signs appear in young puppies and consist of acral analgesia, with or without sudden intense licking, biting and severe self-mutilation of the feet, whereas proprioception, motor abilities and spinal reflexes remain intact. Through a Genome Wide Association Study (GWAS) with 24 affected and 30 unaffected sporting dogs using the Canine HD 170K SNP array (Illumina), we identified a 1.8 Mb homozygous locus on canine chromosome 4 (adj. p-val = 2.5x10^-6). …”

Water protection after tympanostomy (Shepard) tubes does not decrease otorrhea incidence - retrospective cohort study by João Subtil (5629802)

S1 Raw images - by Asadollahi Parisa (8837432)

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Flow cytometry analysis of cancer LS174T and normal IEC-18 cells before and after 120h treatment with bifidobacteria cocktail (100 bacteria/cell), cetuximab and trastuzumab. by Asadollahi Parisa (8837432)

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Primer sequences used for the real time PCR of the genes <i>EGFR</i>, <i>HER-2</i> and <i>PTGS-2</i>. by Asadollahi Parisa (8837432)

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Western blot analysis demonstrating the expression of EGFR, HER-2 and COX-2 proteins in LS174T and IEC-18 cells. by Asadollahi Parisa (8837432)

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Plot of maximum power (a), amplitude (b) and frequency (c) of eel versus roughness of the cylinder. by Muhammad Hammad Bucha (21736111)

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Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing load for the rectus abdominis muscle. by Christoph Anders (4068499)

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing load for the internal oblique muscle. by Christoph Anders (4068499)

Effect sizes (if > 0.5) for the comparison of increasing load vs. decreasing load for the external oblique muscle. by Christoph Anders (4068499)

Increased relative abundance of GPS progenitors and decreased formation of endocrine cells in Cdk4–null mice. by Montse Garcia-Lavandeira (266392)

Deoxysphingolipids – atypical skeletal muscle lipids related to insulin resistance in humans that decrease insulin sensitivity in vitro by Simona Zarini (15332025)

“…<p>  </p> <p>Sphingolipids are thought to promote skeletal muscle insulin resistance. 1-Deoxysphingolipids (dSL) are atypical sphingolipids that are increased in plasma of individuals with type 2 diabetes and cause β-cell dysfunction <em>in vitro</em>. …”