Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…A significant decrease in the response to 5-FU treatment, as well as a significant increase in phosphorylation of IκBα and secretion of IL-8, was seen following IL-1β treatment, in both AA and CA cell lines. …”

Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…A significant decrease in the response to 5-FU treatment, as well as a significant increase in phosphorylation of IκBα and secretion of IL-8, was seen following IL-1β treatment, in both AA and CA cell lines. …”

Image_1_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Table_1_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.docx by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Allelic loss of <i>Cdh11</i> led to faster growing tumors due to decreased cell death. by Mellone N. Marchong (249928)

“…(D) To further support this data, we analyzed for the expression of five pro-apoptotic proteins (activated caspase-3, 8, 9, Trail and Bax) in an additional cohort of <i>Cdh11^+/+;TAg^+/-</i> and <i>Cdh11^-/-;TAg^+/-</i> PND84 animals. …”

Nef Decreases HIV-1 Sensitivity to Neutralizing Antibodies that Target the Membrane-proximal External Region of TMgp41 by Rachel P.J. Lai (193116)

“…Resistance to neutralization by 2F5 and 4E10 was observed with Nef from a diverse range of HIV-1 and SIV isolates, as well as with HIV-1 virions bearing Env from CCR5- and CXCR4-tropic viruses, clade B and C viruses, or primary isolates. …”

Image5_Vaccine induced mucosal and systemic memory NK/ILCs elicit decreased risk of SIV/SHIV acquisition.jpeg by Mohammad Arif Rahman (8267352)

“…<p>SIV and HIV-based envelope V1-deleted (ΔV1) vaccines, delivered systemically by the DNA/ALVAC/gp120 platform, decrease the risk of mucosal SIV or SHIV acquisition more effectively than V1-replete vaccines. …”

Inhibition of ILK Decreases Bipolar and Multipolar Cytokinesis while Increasing Survival of Multinucleated Cells. by William K. A. Sikkema (574881)

Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients by Bai-Wei Gu (740949)

“…Here we describe the production of iPS cells from DC patients with <i>DKC1 </i>mutations <i>Q31E</i>, <i>A353V </i>and <i>ΔL37</i>. …”

Video_5_Decreased levels of discomfort in repeatedly handled mice during experimental procedures, assessed by facial expressions.MP4 by Julia Swan (14556800)

Video_5_Decreased levels of discomfort in repeatedly handled mice during experimental procedures, assessed by facial expressions.MP4 by Julia Swan (14556800)

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Effects of SNPs on the Protein Stability, Increasing or Decreasing. by Mirza Jawad Ul Hasnain (8351388)

DataSheet_1_Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma.pdf by Juan José Nieto-Fontarigo (11800142)

“…</p>Methods<p>Effects of imiquimod alone were examined in HBECs from healthy (N=4) and asthmatic (N=18) donors. Mimicking SARS-CoV-2 infection, HBECs were stimulated with poly(I:C), a dsRNA analogue, or SARS-CoV-2 spike-protein 1 (SP1; receptor binding) with and without imiquimod treatment. …”

The influence of the controlled pH conditions at the sample preparation step on the obtained signals (panel A: extraction using a mixture of MeOH and EtOH; panel B: extraction usin... by Ewa Paszkowska (21246702)

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)

Five main steps of MATSim. by Jingfa Ma (20396406)

“…Results indicate that enhancements in vehicle range and charging efficiency slightly decrease the use of autonomous vehicles by 2.5%, as the existing vehicle specifications already meet daily travel needs in Shanghai. …”