miR-199a-5p decreased invasive ability of ccRCC cells. by Haowei He (734684)

A putative model for the molecular pathway linking hypoxic stress to decreased AQP5 expression. by Jitesh D. Kawedia (384551)

The average speed of the model (step length/step duration), <i>v</i>, vs. the phase of a perturbation pulse, <i>φ</i> for a pulse of constant amplitude and duration. by Jooeun Ahn (299192)

“…<p>When a pulse is located in a swing phase, it cannot accelerate the model, and <i>v</i> is lower than when the entire pulse is inside double stance. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Walking path. by Saori Miyagishima (14593506)

Subjects:

Results of regression analysis performed for age. by Saori Miyagishima (14593506)

Subjects:

Table_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Image_1_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.tif by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”

Fig 5 - by Pierre Bauvin (18154818)

<i>jun-1</i> mutants are highly susceptible to both Bt strains, while <i>elt-2</i> silencing decreased survival on Bt679 but increased survival on Bt247. by Alejandra Zárate-Potes (9415842)

siRNA-mediated knock-down significantly decreases MLL fusion expression levels. by Marieke H. van der Linden (706995)

Mood and reward. by Vasileios Mantas (16949352)

Hypoxia induced decreases in dendritic spine density, length, soma size and volume of the apical and basal branches of CA1 and CA3 pyramidal neurons. by Chun-Sing Lam (695733)

LD- and haplotype-based measures of epistasis identify a narrow time window of epistasis detectability. by Gabriele Pedruzzi (5753792)

Mutation of four arginine residues in P34 leads to a decrease in binding between P34 and L5. by Anyango D. Kamina (4034165)

Detection of epistasis is confined in a time window whose width is controlled by the mean selection coefficient. by Gabriele Pedruzzi (5753792)

Pre-treatment with GnRHa or <i>ulipristal acetate</i> prior to laparoscopic and laparotomic myomectomy: A systematic review and meta-analysis by Inge de Milliano (4515127)

“…Pre-treatment with GnRHa before laparoscopic myomectomies also shows a reduction in intra-operative blood loss by 23.03ml (95% CI -40.79 to -5.27) and in the frequency of blood transfusions (OR 0.17, 95% CI 0.05 to 0.55) compared to no pre-treatment.…”

A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes by Scott A. Salger (3072093)

“…The Class II piscidins (44–46 amino acids in length; striped bass and white bass piscidin 4 and white bass piscidin 5) have a level of activity against bacteria and protozoans intermediate to Classes I and III. …”

Overview of study procedures. by Matthew G. Vinson (22593374)

“…VIDEO and CONTROL were associated with a similar rise in intent to decrease OTC NSAID use (1.92 (SD: 4.41) vs. 1.36 (SD: 3.46), p = 0.150) and a similar decrease in NSAIDs exposure (−32.8% in VIDEO and −36.5% in CONTROL, p = 0.520) 4 weeks post-intervention. …”