Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy by Ahmed, Ashraf Ibrahim

“…The STZ model involved a single injection of STZ (60 mg/kg, i.p.). Behavioral testing for mechanical and heat pain sensitivity was performed using a dynamic plantar aesthesiometer and Hargreaves analgesiometer, respectively. …”
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SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines by Zedan, Hadeel T.

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Characterization of polysulfone/diisopropylamine 1-alkyl-3-methylimidazolium ionic liquid membranes: high pressure gas separation applications by Khraisheh M.

“…TGA showed that pure PSF is a highly thermostable polymer, of which the 5% weight loss temperature is above 150 C. …”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects by Alsaad A.M.

“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by P., Sneha

“…Over the past years, several studies have reported the association of missense mutations in the Hepatocyte Nuclear Factor 1 Alpha (HNF1A) with MODY3. Missense mutations in the POU homeodomain (POUH) of HNF1A hinder binding to the DNA, thereby leading to a dysfunctional protein. …”
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Aqueous Extract Of Origanum Syriacum Inhibits Proliferation, Migration, Adhesion As Well As Erk1/2 Phosphorylation In Aggressive Breast Cancer by Al Kahlout, Amal

“…Moreover, preliminary results indicate that OSE decreased ERK1/2 phosphorylation in MDA-MB-231 cells. …”
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Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia by Fernández-Murray1, J. Pedro

“…The data were consistent with Hem25 not being the sole mitochondrial glycine importer, and we identify a second SLC25 family member Ymc1, as a potential secondary mitochondrial glycine importer. …”
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The retrospective study of the metabolic patterns of BCG-vaccination in type-2 diabetic individuals in COVID-19 infection by Anwardeen, Najeha R.

“…Furthermore, data indicated a decrease in sarcosine synthesis from glycine and choline and increase in spermidine synthesis in the BCG vaccinated cohort in T2D and non-T2D groups, respectively. …”
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Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis by Elleuch, Jihen

“…However, a protection against excessive degradation of protoxin and toxin forms of Cry1Ac was strongly decreased in the case of δ-endotoxins produced in the presence of P20 as compared to those from P20 lacking control. …”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells by Zibara, Kazem

“…In conclusion, we demonstrated that PACAP signaling in MCF-7 cells follows the Src/Raf/ERK and PI3K/AKT pathways and is VPAC1 dependent in a ROS dependent manner, whereas it follows PLC and PKA/cAMP pathways and is VPAC2 dependent through p38 MAP kinase activation involving calcium.…”
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Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events by Raj, K. Diraviya

“…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …”
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Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation. by Saleh, Alaaeldin I

“…However, the effect of EA plant extract on human cancers especially oral has not been investigated yet. Thus, first we examined the outcome of EA flower extract on angiogenesis, using the chorioallantoic membrane (CAM) of the chicken embryo; we found that EA extract reduces blood vessel development of the CAM. …”
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The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages by Al-Awad, Duha

“…We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …”
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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase by Abdulrahman N.

“…We have previously demonstrated that elevated NHE1 activity induced cardiac hypertrophy in vivo. …”
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Deep Reinforcement Learning Powered IRS-Assisted Downlink NOMA by Shehab, Muhammad

“…In this work, we examine an intelligent reflecting surface (IRS) assisted downlink non-orthogonal multiple access (NOMA) scenario intending to maximize the sum-rate of users. …”
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Evaluation of antibody response in symptomatic and asymptomatic covid-19 patients and diagnostic assessment of new IgM/IgG elisa kits by Al-Jighefee, Hadeel T.

“…This study aims to study the immune response and evaluate the performances of four new IgM and five IgG enzyme-linked immunosorbent assay (ELISA) kits for detecting anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies against different antigens in symptomatic and asymptomatic coronavirus disease 2019 (COVID-19) patients. …”
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart by Akhtar, Saghir

“…Aim: The influence of the physiochemical properties of dendrimer nanoparticles on cardiac contractility and hemodynamics are not known. Herein, we investigated (a) the effect of polyamidoamine (PAMAM) dendrimer generation (G7, G6, G5, G4 and G3) and surface chemistry (-NH2, -COOH and -OH) on cardiac function in mammalian hearts following ischemia-reperfusion (I/R) injury, and (b) determined if any PAMAM-induced cardiotoxicity could be mitigated by Angiotensin-(1-7) (Ang-(1-7), a cardioprotective agent. …”
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An evidence base for school health policy during the covid-19 pandemic by Badran, S.

“…Further data suggested decreased childhood transmission from respiratory droplets and a low viral load among children. …”
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Alhujaily, Muhanad

“…Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase system. We investigated the role of MG and Glo1 in cancer chemotherapy related in multidrug resistance (MDR). …”
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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. by Gomes da Silva, Isaura Isabelle Fonseca

“…Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …”
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