Showing 301 - 320 results of 104,764 for search '(( 1 wt decrease ) OR ( 5 ((((fold decrease) OR (point decrease))) OR (a decrease)) ))', query time: 1.62s Refine Results
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    Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T... by Jiaxing Zhao (3965057)

    Published 2022
    “…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC<sub>(tofacitinib, 0–∞)</sub> and a 9.61-fold increase of colonic AUC<sub>(tofacitinib, 0–12h)</sub>, compared with tofacitinib at a molar equivalent oral dose. …”
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    Transcriptomic and metabolomic analyses of liver of <i>Fmo5</i><sup><i>-/-</i></sup> and WT mice. by Ian R. Phillips (5074121)

    Published 2023
    “…<p>(A) Volcano plot representation of differentially expressed genes (log<sub>2</sub>-fold change) of <i>Fmo5</i><sup><i>-/-</i></sup> vs WT mice. …”
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    GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

    Published 2017
    “…(<b>D,E</b>) The channel open probability was evaluated by measuring the degree of MTSEA (200 μM) potentiation using TEVC recordings from <i>Xenopus</i> oocytes expressing the WT GluN2A (<i>left panel</i>) or the mutant GluN2A(D731N) (<i>right panel</i>) coexpressed with GluN1(A652C) at a holding potential of -40 mV in presence of EC<sub>50</sub> concentrations of glutamate with saturating concentration (100 μM) of glycine (open bar) and 0.2 mM MTSEA (closed bar). …”